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Magnesium sulfate, potassium chloride, and sodium sulfate

Generic Name: Magnesium sulfate [mag-NEE-zee-um], potassium chloride, and sodium sulfate Poe-TASS-ee-um -SUL-fate -KLOR-ide, as well as -SOE-dee-um -SUL-fate].
The Brand Name: Sutab.
Dosage Format: Oral tablet (0.225 g–0.188 g–1.479 grams).
Drug Class: Laxatives.

What are magnesium sulfate, potassium chloride, and sodium sulfate (Sutab)?

Magnesium, potassium, and sodium are electrolyte mineral substances that occur naturally in bodily fluids.

Magnesium and potassium, as well as sodium sulfates (Sutab), are combination medications that can cause diarrhea and aid in cleaning your colon prior to a colonoscopy. Cleaning your colon (bowel prep) will allow the interior of your colon to be seen more clearly when you have a colonoscopy. Magnesium and potassium, as well as sodium sulfates, are also employed for reasons not mentioned in this guideline for medication.

Adverse negative effects magnesium sulfate, potassium chloride, and sodium sulfate

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, and swelling of your lips, face, or tongue. See your doctor as soon as possible. If you are suffering from:

  • Trouble drinking liquids.
  • Nausea, painful bloating, stomach cramps, vomiting.
  • Minimal or no urination.
  • A seizure.
  • Bleeding in the rectal area.
  • Symptoms of an electrolyte imbalance: increased thirst or urination, disorientation, or slurred speech. Dizziness and weakness You may also feel jittery or unsteady constipation, muscle pain or weak legs, tingling or numbness, irregular heartbeats, and a feeling of flutter within your chest.

Common adverse effects of magnesium sulfate, potassium chloride, and sodium sulfate can be:

  • Stomach pain or discomfort.
  • Nausea, vomiting.
  • Moderate constipation.

This is not an exhaustive list of probable adverse effects; more may occur. Consult your physician to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.


This medication may cause extreme dehydration, which can result in a serious electrolyte imbalance. This can lead to seizures as well as the kidneys failing. Consult your doctor if you are vomiting and you aren't drinking enough water to prepare your bowels or if you experience symptoms of headache, dizziness, headache, or reduced frequency of urination.

Before you take this drug

You shouldn't take Sutab if you're allergic to magnesium sulfate as well as potassium sulfate or sodium sulfate. If you suffer from:

  • An obstruction in the bowel, colitis, or toxic megacolon.
  • A dilated intestine.
  • Perforations (a tear or hole) in your intestinal tract.
  • Slow digestion.

Inform your doctor if you were ever diagnosed with:

  • Heart problems, including long QT syndrome.
  • A stomach or intestinal condition like ulcerative colitis.
  • Gastroesophageal reflux disease (GERD).
  • Difficulty swallowing.
  • An electrolyte imbalance (such as having low amounts of magnesium, potassium, and sodium).
  • A seizure.
  • Kidney disease kidney disease.
  • If you're suffering from alcohol addiction or are addicted to the drug Valium-like or similar sedatives (benzodiazepines).

Inform your doctor if you are breastfeeding or pregnant. This medicine is not authorized to be used by anyone less than 18 years old.

How to take magnesium sulfate and potassium chloride sodium sulfate

Follow all instructions on the label of your prescription and read the medication guide or instructions sheets. Follow the medication exactly as prescribed. Be sure to follow the instructions on what to eat and drink during the days prior to your bowel prep and when you should quit eating solid foods. Sutab is typically taken in two doses. Each dose comprises 12 tablets taken at a time and 16 fluid ounces. The first dose is taken in the evening prior to your colonoscopy. Then, take another dose in the morning before your colonoscopy. Be sure to read and adhere to any instructions for use that are included in your medication. Talk to your pharmacist or doctor if you don't understand these directions. It is necessary to drink more water when you begin your bowel preparation. Drink only clear fluids and stay clear of milk, alcohol, or any beverage that is purple or red. You must finish every dose at least 2 hours prior to your colonoscopy. This medicine may cause extreme dehydration that could result in a serious electrolyte imbalance, seizures, and kidney damage. Call your doctor in the event that you suffer from vomiting and are unable to drink enough fluids to support your bowel preparation or if you experience headaches, dizziness, a feeling of drowsiness, or a decrease in the frequency of urination. Keep the room at room temperature.

What happens if I miss a dose?

Consult your physician if you are unable to drink the full amount of liquids and medicines as directed prior to your colonoscopy.

What happens if I overdose?

It is highly unlikely that an overdose will occur if you use magnesium sulfate, potassium chloride, and sodium sulfate in the exact manner instructed.

What should be avoided?

Do not take any other laxatives to aid in bowel preparation.

Interaction with other drugs

Sutab may make it difficult for the body to properly absorb other medications you take orally. Avoid taking any oral medicine for at least 1 hour prior to starting Sutab. If you are taking any of these medicines, take the Sutab dose six hours prior to or two hours after taking another medicine.

  • Chlorpromazine.
  • Digoxin.
  • Iron.
  • Certain antibiotics—ciprofloxacin, delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, ofloxacin, penicillamine, and tetracycline.

Inform your doctor about all other medicines you take, particularly:

  • Medicine for blood pressure or heart.
  • A diuretic, or "water pill".
  • Treatment for a kidney issue.
  • Medicines to treat depression and mental illnesses.
  • Seizure medication.
  • The NSAIDs (nonsteroidal anti-inflammatory drugs) are aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac (also known as indomethacin), diclofenac, diclofenac, and many more.

This list is not comprehensive. Other medications can affect Sutab, such as prescription and over-the-counter medicines, vitamins, and herbal products. Some interactions with drugs are not listed here are included here.