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Meloxicam

Generic name: Meloxicam (oral or injection) [mel-OKS-i-kam]
Brand names: Anjeso, Mobic, Vivlodex, Qmiiz ODT
Dosage forms: Intravenous dispersion (30 mg/mL), oral capsule (10 mg; 5 mg), oral suspension (7.5 mg/5 mL), Oral tablet (15 mg; 7.5 mg).
Class of drug: Nonsteroidal anti-inflammatory drugs

What is Meloxicam?

Meloxicam is an anti-inflammatory nonsteroidal drug (NSAID). It is effective in reducing the hormones that cause fever, pain, and inflammation within the body.

Meloxicam can be used to ease the pain, tenderness, swelling, and stiffness that are caused by osteoarthritis (arthritis due to the breakdown of the joint's lining) and Rheumatoid arthritis (arthritis due to the swelling of the linings of the joints).

Meloxicam can also be used to reduce the tenderness, swelling, stiffness, and pain due to juvenile Rheumatoid arthritis (a kind of arthritis that is prevalent in children) in children who are 2 years old or older.

Anjeso is an alternative to the Anjeso version of the medication used for treating moderate to severe pain in adults.

Villodex is intended for use only by adults. QmiizODT is designed for children and adults who weigh at least 132 lbs (60 kg).

Warnings

Meloxicam could increase your chances of a fatal stroke or heart attack, particularly if you take it for long periods, take high doses, or suffer from heart disease. Even those without heart disease or risk factors may be at risk of a heart attack while taking this medication.

Do not take this medication immediately prior to or after coronary bypass surgery (coronary bypass graft for the artery, also known as CABG).

Seek medical attention immediately for chest discomfort, breathing problems, shortness of breath, or slurred speech. issues with balance or vision.

Meloxicam can also trigger diarrhea or stomach bleeding, which could be fatal. These problems can develop at any time while taking this medication and are more common among older adults.

Contact your doctor immediately. If you notice signs of stomach bleeding like bloody or black stools, or if you're coughing out blood or vomiting that resembles coffee grounds,

Beware of drinking and smoking because they can increase the chance of bleeding from your stomach.

Before Taking this Medication

Meloxicam increases the chance of having a fatal stroke or heart attack. Avoid using this medication immediately prior to or after coronary bypass surgeries (coronary bypass graft for the artery, also known as CABG). Meloxicam can also trigger diarrhea or stomach bleeding, which could be fatal.

Meloxicam could also cause stomach or intestinal bleeding, which can lead to death. These issues can happen at any time while taking this medication, particularly among older adults.

It is best not to use meloxicam in the event that you are allergic to it or if you have previously had an asthma attack or an extreme allergic reaction after using aspirin or an NSAID.

To ensure that meloxicam is suitable for you, ask your doctor if you've previously had:

  • Heart disease, hypertension, high cholesterol, diabetes, heart disease, or smoking cigarettes;
  • A Heart attack, stroke, or blood clot
  • Gastric ulcers or bleeding from the stomach;
  • Asthma;
  • Kidney disease (or if you're taking dialysis);
  • Liver disease or
  • Fluid retention.

If you are expecting, then you shouldn't take Meloxicam unless your physician tells you not to. Taking an NSAID in the final twenty weeks of pregnancy could cause kidney or heart issues in the baby and may cause complications during the pregnancy.

Meloxicam can delay the process of ovulation (the release of eggs from the ovary). This medication is recommended if you're taking fertility treatments or if you're trying to become pregnant.

Consult your doctor to determine whether it is safe to breastfeed while taking this medication.

Meloxicam is not approved for use by children younger than 2 years of age.

How to Take Meloxicam?

Use Meloxicam according to the prescription given by your physician. Follow the directions on the prescription label. Also, review all medication guides and instruction sheets. Make sure you are taking the dose that is most effective for treating your condition.

Meloxicam oral tablets are taken by mouth.

Meloxicam injections are given as an injection into a vein. Your healthcare professional will offer the injection.

The dosage you require can change if you change to a different brand, strength, or version of Meloxicam. Be sure to use only the medication your doctor has prescribed.

The doses of Meloxicam are based on weight (especially for teenagers and children). Your dose needs may change if you gain or lose weight.

If you take this medication for a long time, you might require regular medical examinations.

Keep oral suspension tablets or capsules at ambient temperature, away from heat and moisture. The bottle should be kept tightly shut when not in use.

Details on Dosage

Usual Adult Dose for Osteoarthritis:

Oral Tablets and Oral Disintegrating Tablets:
Initial dosage: 7.5 mg orally once per day.
Maintaining dose: 15 mg taken orally daily in patients who require additional analgesia.
Maximum dose: 15 mg taken orally, at least once per day.

Oral Capsules:
Initial dose: 5 mg taken orally at least once per day.
Maintaining dosage: 10 mg orally, once daily, for patients who require additional analgesia
Maximum dosage: 10 mg taken orally every day.

Use: To alleviate the symptoms and signs of osteoarthritis pain.

Usual Adult Dose for Rheumatoid Arthritis:

Oral Tablets and Oral Disintegrating Tablets:
Initial dosage: 7.5 mg orally once every day.
Maintenance dosage: 15 mg orally daily in patients who require analgesia with additional dosage
The maximum dose is 15 mg, taken orally twice per day.

Use: To relieve the symptoms and signs of rheumatoid arthritis.

Usual Adult Dose for Pain:

30 mg IV Bolus (over fifteen seconds) at least once per day

Comments:
The median time for effective pain relief was between two and three hours during clinical studies. A non-NSAID with a quick start may be required for some patients; however, they may not feel adequate analgesia during the first 24 hours.
The dose that is the least effective in the shortest time and that is in line with the treatment goals of each patient should be taken.

Use: To manage the symptoms of moderate-to-severe pain. It can be used on its own or in combination with analgesics that are not NSAIDs.

 

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

2 years old or older:
Oral Tablets and Oral Disintegrating Tablets:
Weight at 60 kg or more: 7.5 mg orally once per day.
There is no additional benefit established with dosages that exceed 7.5 mg per day.

Comments:
Oral formulations are not able to demonstrate similar systemic exposures and cannot be considered interchangeable.
The tablets for oral use are not recommended for children weighing less than 60 kilograms.
Use: To alleviate symptoms and signs of polyarticular or particular juvenile arthritis. Rheumatoid arthritis.

What Happens If I Miss a Dose?

Take the medication as quickly as you can; however, take a break from any missed doses if you are nearing the time to take the next dose. Don't take two doses at once.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What Should be Avoided?

Alcohol consumption can increase the chance of bleeding from your stomach.

Take care not to take aspirin when you take meloxicam or unless your doctor advises you to.

Consult a physician or pharmacist prior to using any other medicines to treat discomfort, swelling, and fever, as well as swelling and symptoms of a cold or flu. They could contain ingredients that are similar to meloxicam (such as aspirin, Ibuprofen, ketoprofen, or naproxen).

Side Effects of Meloxicam

Contact a medical professional immediately when you notice symptoms that you are experiencing an allergic reaction to meloxicam (hives, breathing difficulties, or swelling in your throat or face) or a severe reaction to your skin (fever or burning eyes, sore throat, and skin irritation, as well as red or purple skin that blisters and peels).

Take immediate medical care. If you are experiencing indications of an attack on your heart or stroke, chest pain spreading into your shoulder or jaw, suddenly feeling numb or weak in one area of your body, slurred speech, leg swelling, or feeling tired

Meloxicam can cause severe adverse effects. Stop taking this medication and consult your physician immediately if you suffer from:

  • The initial sign of an itchy rash, no matter how slight
  • Breathlessness (even when exerting only a little)
  • Weight gain or swelling
  • Indications that stomach blood is bleeding, bloody or tarry stool, coughing blood, or vomiting that looks like coffee grounds
  • liver issues The symptoms include nausea. nausea, stomach pain Itching, fatigue, flu-like symptoms, and lack of appetite black stools; dark urine; jaundice (yellowing of the eyes or skin)
  • Red blood cell count is low (anemia): pale skin, unusual fatigue sensation of lightheadedness, cold feet and hands,
  • Kidney issues There is no or little urine, swelling of your ankles or feet, and feeling tired or exhausted.

Common side effects of meloxicam could include:

  • Abdominal pains, nausea, and heartburn
  • diarrhoea, constipation, gas
  • dizziness
  • symptoms of a cold flu symptoms, cold symptoms

This is not a comprehensive list of all the side effects. Other side effects could occur. Contact your physician for advice regarding medical adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with Other Drugs

Consult your physician before using meloxicam when you take medication for depression. Taking certain antidepressants together with an NSAID could cause bleeding or bruises.

Discuss with your doctor all other medications, including:

  • Cyclosporine
  • Lithium;
  • Methotrexate
  • Pemetrexed
  • Sodium polystyrene Sulfonate (kayexalate)
  • A bleeding thinner (Warfarin, Coumadin, Jantoven)
  • Blood pressure or heart-related medication, such as diuretics and a "water pill
  • Steroid medicine (such as prednisone)

This list isn't exhaustive. Other medications can be incompatible with meloxicam, such as medications that are prescribed and available over the counter, vitamins, and herbal supplements. Some interactions with drugs are not listed here. are included here.

 

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