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Name of the Generic: Balsalazide [bal-SAL-a-zide] Bal-SAL-azide
The Brand Names are: Colazal and Giazo.
Dosage Form: Oral capsule (750 mg)
The Class of Drug: 5-aminosalicylates

What is a Balsalazide?

The Colazal Balsalazide brand has been used for treating moderate to mild active ulcerative colitis in both children and adults who are older than 5 years.

It is known as the Giazo version of balsalazide and can be used for the treatment of mild-to-moderately active colitis in males who are at least 18 years old. Balsalazide is also employed for other purposes that are not covered in this guideline.

Side Effects of Balsalazide

See a doctor immediately. Get medical attention immediately if you notice symptoms that are warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, and tongue.

Adverse Effects:

  • Burning or pain after you urinate.
  • More severe symptoms of colitis more severe colitis symptoms: symptoms that are worsening include fever, stomach pains, and cramps; bleeding diarrhea.
  • Kidney problems: little or no urination or swelling, rapid weight gain.
  • Liver issues: upper stomach pain and loss of appetite dark urine, stools that are clay-colored, jaundice (yellowing of the eyes or skin), as well as.
  • Red blood cells are low (anemia)—pale skin, uncharacteristically tired, lightheaded or sluggish, cold hands and feet.

Common negative side effects of balsalazide include:

  • Headache.
  • Moderate or occasionally symptoms of nausea, vomiting, stomach pain, diarrhea, and nausea.
  • Joint pain.
  • Fever.
  • Signs of a cold, like congestion, sneezing, and a sore throat.

This isn't a complete list of possible side effects, and other side effects could occur. Contact your physician to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Follow the directions on the label of your medication and the package. Be sure to inform your healthcare professionals about your medical ailments, allergies, and any medications you take.

Before you this drug

It is not recommended to use balsalazide in the event that you are allergic to mesalamine, balsalazide, aspirin, or different salicylates (including Kaopectate Pamprin or Pepto Bismol). Tricosal, trilisate, and other salicylates).

Speak to your doctor if you are ever diagnosed with:

  • kidney disease
  • The liver condition
  • A stomach disorder known as pyloric stasis.

Balsalazide tablets are laced with sodium. Consult your physician before taking this form of balsalazide if you are on a diet low in salt.

Inform your physician if you are expecting or plan to be pregnant. It isn't known if balsalazide can affect a newborn baby. However, the presence of ulcerative colitis in pregnancy can lead to premature birth or a baby with a low birth weight. The advantages of treating ulcerative colitis could outweigh the risks to the infant. If you're nursing, inform your doctor if you observe diarrhea in your nursing infant. Balsalazide capsules shouldn't be given to children under five years old. It is recommended that balsalazide tablets not be distributed to anyone younger than 18 years old.

How to take Balsalazide?

Follow the instructions on the prescription label and also read all medication guides or instruction sheets. Follow the medication precisely as directed. Balsalazide is taken with or without meals.

If you are unable to swallow the capsule completely, break it and then sprinkle the medication into one spoonful of applesauce. Drink the liquid immediately. The medicine in the capsule could make your teeth or tongue orange or yellow when mixed with food. Don't save the capsule to use later on. Consult your doctor if symptoms don't improve or if they become worse. Balsalazide is typically taken for a brief period of time (8 or 12 weeks). Follow the doctor's instructions for dosage with care. Keep at room temperature, away from heat and moisture.

Details on dosage

Usual Adult Dose for Ulcerative Colitis (Active):

Oral capsules:
Usual dosage 3 capsules of 750 mg daily, orally, for up to 8 weeks.
Some patients who participated in clinical trials needed as long as 12 weeks to undergo treatment.
Efficacy and safety beyond 12 weeks haven't been proven.
GIAZO (R) tablets; male patients:
Three 1.1-gram tablets, taken every day, whether with or without food, during up to eight weeks
Efficacy in female patients has not been proven in clinical studies.
The safety and efficacy of the product beyond 8 weeks haven't been proven.

Treatment of moderately active to mildly active ulcerative colitis

Usual Pediatric Dose for Ulcerative Colitis (Active):

5 years or older Oral capsules for children 5 years old and over:
Three 750 mg capsules taken orally three times per day for up to 8 weeks
One capsule of 750 mg, three times daily, until 8 weeks

Safety and efficacy after 8 weeks haven't been established.

To treat moderately active to mildly active ulcerative colitis.

What happens if I miss a dose?

Do not take the medicine for as long as you can. However, avoid your missed dose if you are nearing the time to take the next dose. Don't take two doses at once.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Follow the instructions of your physician regarding any restrictions on your food, drink, or activity.

Interaction with other drugs

Other drugs can interact with balsalazide, such as prescription and non-prescription medicines, vitamins, and herbal products. Discuss with your doctor all the medicines you are currently taking as well as any medications you are about to start or stop taking.



Prescription only

Pregnancy & Lactation

CSA Schedule*

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