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Pheniramine and phenylephrine

Generic name: pheniramine and phenylephrine [fen-IR-a-meen-and-FEN-il-EFF-rin]
Brand name: Alahist D
Dosage format: oral tablet (17.5 mg–10 mg)
The class of drug: upper respiratory combinations

What are Pheniramine and phenylephrine?

Pheniramine and phenylephrine are antihistamine, decongestant, and antihistamine medicines that treat runny or stuffy noses and sneezing. It can also be used to treat itching eyes, watery eyes, and sinus congestion that is caused by allergies, as well as the general cold and influenza.

Phenylephrine and pheniramine can also be used for reasons that are not mentioned in this guide.

Side effects

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and throat,

Phenylephrine and pheniramine may result in serious adverse effects. Stop taking phenylephrine or pheniramine, and consult your physician anytime if you experience:

  • Nervousness;
  • Dizziness; or
  • Trouble sleep.

Common negative effects of pheniramine and phenylephrine can be:

  • drowsiness;
  • Being anxious or restless (especially when it comes to children);
  • Dry mouth the nose, mouth, or throat;
  • Constipation or
  • Blurred vision double vision, blurred vision

This isn't a complete list of possible side effects, and other side effects could occur. Consult your physician for advice regarding medical adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


Do not take the medicine to make your child restless. Misuse of this medicine could result in death for extremely young kids.

Prior to use this drug

Pheniramine is not a good choice, nor is phenylephrine, if you are allergic to pheniramine and phenylephrine.

Don't use pheniramine or phenylephrine if you have taken an MAO inhibitor within the past 14 days. A potentially dangerous interaction between the two drugs could happen. MAO inhibitors are isocarboxazid linezolid, methylene blue injection, phenelzine, and tranylcypromine, as well as other MAO inhibitors.

Consult a pharmacist or doctor for a recommendation on whether this medicine is safe to use if:

  • Asthma or another breathing disorder such as emphysema, as well as chronic bronchitis;
  • High blood pressure; heart disease;
  • An enlarged prostate and urinary tract problems
  • Glaucoma;
  • Diabetes or
  • A thyroid condition.

Don't give the medication to a child less than 6 years old unless you have medical guidance.

How to take?

Follow the directions on the label or as recommended by your physician. A cold and allergy medication is intended to be used for a short time until symptoms improve.

Follow the instructions on the medication label regarding the administration of cold or cold medicines to children. Don't use the medicine to only cause a child to be sleepy. Death can occur because of the misapplication of cough or cold medicine to children as young as Consult your doctor if symptoms don't improve after seven weeks of therapy or if you suffer from a fever that is accompanied by symptoms such as a headache, cough, or a skin eruption.

If you require an operation or tests for medical reasons, inform your doctor or surgeon before the appointment time if you have taken this medication in the last couple of days. Keep at room temperature, far from heat, humidity, and light.

Details on dosage

Usual Adult Dose for Allergic Rhinitis:

Pheniramine 17 mg/phenylephrine 10mg tablets: One tablet to be taken orally every 4 hours
Maximum dosage of 6 tablets over 24 hours
Time of therapy The duration of therapy is 7 days.

Utilization: Temporary alleviation from allergies and cold signs (rhinorrhea, sniffing, nasal congestion, itchy nose, eyes, or throat).

Usual Pediatric Dose for Allergic Rhinitis:

Pheniramine 17 mg/phenylephrine 10 mg tablets:

12 years old and over 1 tablet every 4 hours
Maximum dosage of 6 tablets over 24 hours
Therapy duration: 7 days

From 6 to 12 years old 1 tablet taken orally every 4 hours
Maximum dosage: 3 tablets per 24 hours.
The duration of therapy is 7 days.

Utilization: Temporary alleviation from allergies and cold symptoms (rhinorrhea or sneezing), nasal congestion, and an itchy nose, eyes, or throat.

What happens if I miss the dose?

Because pheniramine and phenylephrine are employed when required, it is possible that you are not in a prescribed dosing routine. Do not miss any doses when it's time for the next dose. Don't take two doses in one go.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you understand the way phenylephrine and pheniramine influence your body. Your reaction may be impaired.

Talk to your doctor or pharmacist prior to using any other cough or cold medications that may have similar components.

Alcohol consumption can cause an increase in the effects of pheniramine in certain ways.

Interaction with other drugs

Consult a physician or pharmacist prior to taking other medications that could result in the feeling of drowsiness (such as opioids, sleep medication, a muscle relaxer, or medications to treat anxiety as well as seizures). The interactions of all medications are not described here.