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Gadoxetate

Generic name: Gadoxetate [gado-OXe-tate]
Brand names: Eovist
Intravenous Solution: Intravenous Solution (181.43 mg/mL).
Drug class: Contrast media for magnetic resonance imaging

What is Gadoxetate?

It is a contrast agent with magnetic properties. The contrast agent is used with magnetic resonance imaging to make blood vessels, organs, and non-bony tissue more visible. Gadoxetate can be used to diagnose liver disorders. This medication guide does not list all possible uses of gadoxetate.

Side effects of Gadoxetine

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat. Gadoxetate can cause side effects up to a few days after the injection. People with advanced kidney disease can be at risk of a life-threatening situation when they are exposed to gadoxetate. If you experience any of the symptoms of this condition, call your doctor immediately.

  • Burning, itching, and swelling of the skin are all symptoms.
  • Tiredness, muscle weakness;
  • Joint stiffness of the arms, legs, or feet
  • Deep bone pain in the ribs and hips
  • Trouble moving
  • Skin redness or dark patches

Call your doctor immediately if you:

  • Kidney problems: no or limited urination; painful or difficult urination; swelling in feet or ankles; feeling fatigued or short of breath are symptoms that should not be ignored.
  • The injection site may be affected by swelling, irritation, or changes in the skin.

Gadoxetate side effects may include:

  • Headache, back pain;
  • Dizziness;
  • Nausea;
  • Feeling hot

There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA with any side effect reports can be done at 1-800-FDA-1088.

Similar/related drugs

Eovist

Warnings

Gadoxetate may cause serious side effects in patients with advanced kidney disease. This medication should not be taken by people with kidney disease or those on dialysis.

Before you take this drug

Gadoxetate may cause serious side effects in patients with advanced kidney disease. This medication should not be taken by people with kidney disease or those on dialysis. Gadoxetate may remain in your body for months or even years after receiving it. This is not known to cause health problems for people with healthy kidneys. Tell your doctor that you've had scans using a contrast agent multiple times and give the date of your most recent scan. If you have an allergy to gadoxetate, it is best not to receive the drug.

Inform your physician of any of the following issues:

  • Health issues; imunitar Reaction to contrast agents
  • Diabetes;
  • High blood pressure
  • Liver disease
  • Asthma; hay fever; food or drug allergy
  • An injury, surgery, or severe infection;
  • If you are older than 60,

This medicine is not known to harm an unborn child. Inform your doctor if you are pregnant. Do not breastfeed your baby for at least 10 hours after you receive gadoxetate. Throw away any milk that you have collected if you are using a breast pump. Do not give it to your child.

How to take Gadoxetate?

Gadoxetate can be infused into a vein. This injection will be given by a healthcare provider. If you experience any pain or swelling when Gadoxetate IV is injected, tell your caregivers. You may be asked to stay under observation by your doctor or another healthcare provider for a few minutes after the test. Make sure that there are no side effects or delayed reactions with any medication you use. Gadoxetate can have an influence on certain medical tests for up to 24 hours post MRI, such as CT or PET/CT scan results. It could alter these test outcomes or have other unfavorable impacts as a result of its consumption.

Details on dosage

Adult dose for liver magnetic resonance imaging:
The dose is 0.1 mL/kg of body weight (0.025 mmol/kg) given undiluted in a single intravenous injection with a flow rate of around 2 mL/second.

What happens if I miss the dose?

You will not have a schedule for gadoxetate dosing since it is only used during the MRI.

What happens if I overdose?

Overdoses are unlikely because gadoxetate will be administered by a healthcare provider in a medical environment.

What should be avoided?

If your doctor suggests any restrictions pertaining to food, beverage or activity consumption or physical activities, be sure to heed their orders and adhere to them strictly.

Interaction with other drug

Gadoxetate can be affected by other drugs, such as vitamins and herbal products. Informing your physician of all medicines you are currently taking or plans to start or stop taking is very important.