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Generic name: ethinyl estradiol and norethindrone (HRT) [ETH-in-ill-ESS-tra-DYE-ole-and-nor-ETH-in-drone]

Brand name: Femhrt 0.5 mg/2.5 mcg
Drug classes: contraceptives, sex hormone combinations

What is Femhrt?

Femhrt is made up of ethinyl esteradiol as well as norethindrone. Ethinyl estradiol is a type of estrogen. Estrogen is a female sexual hormone that is essential for a variety of processes within the body. Norethindrone is a type of progesterone. Progesterone, a female hormone, is essential for the regulation of menstrual cycles and ovulation.

Femhrt is a treatment for symptoms of menopausal symptoms, including hot flashes and vaginal dryness, burning, irritation, and hot flashes.

Femhrt is also employed to reduce osteoporosis following menopausal changes.


You should not take Femhrt if you suffer from undetected vaginal bleeding or liver disease, bleeding problems, if you are planning to undergo major surgery, if you've ever suffered a heart attack or stroke, a blood clot, breast cancer, or the uterus, cervical, or vagina.

Femhrt may result in a birth defect. Do not take it if you're pregnant. Inform your doctor immediately when you become pregnant or if you have missed two menstrual periods in one row.

This medicine could increase the risk of becoming a victim of a disorder that can result in cancer of the uterus. Inform your doctor about any unusual vaginal bleeding immediately.

Utilizing this medicine may increase the risk of blood clots, heart attacks, strokes, and cancer of the uterus, breast, or ovaries.

Femhrt shouldn't be used to treat stroke, heart disease, and dementia since this medication can increase the likelihood of developing these diseases. In the long run, it could increase the risk of breast cancer and blood clots.

Similar/related drugs

alendronate , estradiol , Fosamax , Premarin , Reclast , Estrace , The drug raloxifene

Prior to use this drug

Femhrt is not recommended when you have an allergy to norethindrone or ethinyl estradiol or suffer from:

  • Abnormal vaginal bleeding that isn't being examined by an ophthalmologist;
  • Liver disease;
  • A bleeding disorder;
  • An underlying past history of stroke, heart attack, or a blood clot;
  • An antecedent history of hormone-related cancer, which includes cancer of the breast, cervical uterus, or vagina.

Do not take Femhrt when you are expecting. Tell your doctor immediately if you find yourself pregnant while receiving treatment.

Utilizing this medication may increase the risk of blood clots, strokes, or heart attacks. You're more at risk if you suffer from elevated blood pressure and diabetes, elevated cholesterol, and if you're overweight or smoke.

Femhrt shouldn't be used to stop stroke, heart disease, or dementia, as the medication could increase the risk of developing these diseases.

To ensure that femhrt is safe for you, inform your doctor if you ever experience:

  • Heart disease;
  • Liver issues and jaundice due to the pregnancy process or by taking hormonal medications;
  • Kidney disease;
  • Hereditary angioedema (an illness of the immune system);
  • Bone cancer;
  • Lupus;
  • Asthma;
  • Epilepsy or any other seizures;
  • Migraines;
  • Porphyria (a genetic disorder of enzymes that results in symptoms that affect the nervous system, skin, or nerves);
  • Gallbladder diseases;
  • Endometriosis or uterine fibroid tumors;
  • A thyroid disorder
  • Low or high levels of calcium in your blood.

Femhrt use can increase your risk of getting cancer of the uterus, breast, or ovaries. Consult your doctor regarding this possibility.

This medication can reduce the production of breast milk. Consult your physician if you are breastfeeding.

How to take Femhrt?

Use femhrt exactly as was prescribed to you. Follow the instructions on the label of your prescription and read the medication guide or instructions sheets. Take this medicine daily at the same time, every day.

Femhrt could increase your chance of developing an illness that could cause cancer of the uterus. To reduce the risk, your physician may decide to prescribe an estrogen-like progestin. Inform your doctor of any vaginal bleeding that is unusual right now. Your doctor will be able to check your development regularly (every 3 to six months) to determine if you are able to continue the treatment. Examine the breasts to detect lumps every month and get regular mammograms.

If you are in need of major surgery or are being placed on bed rest for long periods of time, you may have to discontinue using this drug for a brief period of time. Any surgeon or doctor who treats you must be aware that you're taking Femhrt. Keep it at room temperature, far from heat and moisture.

What happens if I miss a dose?

Do not take the medicine for as long as you can. However, do not take any missed doses if it's nearing the time to take the next dose. Don't have two doses at one time.

What happens if I overdose?

For medical emergencies, seek emergency attention or contact the Poison Help Line at 1-800-222-1222. The signs of an overdose could consist of a feeling of nausea, vomiting, and vaginal bleeding.

What should be avoided?

Don't smoke. Smoking increases the chances of developing blood clots, heart attacks, and strokes when using femhrt.

Grapefruit could interact with ethinyl estradiol as well as norethindrone, causing undesirable negative side effects. Do not use grapefruit-related products.

Side effects of Femhrt

Contact a medical professional immediately. If you exhibit symptoms of an allergy reaction, the first is hives, difficulty breathing, or swelling of your lips, face, and throat.

Stop taking this medicine and consult your physician immediately if you experience:

  • Warning signs of heart attacks heart attack symptoms: chest pain, pressure, pain that spreads to your shoulder or jaw, nausea, sweating, or vomiting;
  • Higher blood pressure high blood pressure, extreme headache blurred vision, tapping in your neck or ear, anxiety, nosebleeds
  • Indications of sTroke sudden weakness or numbness (especially in one part of your body) or an extreme headache that is sudden and slurred speech. Also, issues with balance or vision;
  • Indications of the presence of a bleeding clot—sudden loss of vision or chest pain. feeling tired and coughing up blood. heat or pain on one or both legs;
  • The tenderness or swelling of your stomach;
  • Jaundice (yellowing of the eyes or skin);
  • Abnormal bleeding from the vagina or pelvic pain
  • A breast lump
  • Memory issues or confusion, abnormal behavior, or
  • High levels of calcium present in the blood cause nausea, constipation, more frequent urination or thirst, weakening muscles, bone pain, and a lack of energy.

Common side effects from femhrt include:

  • Stomach pain;
  • Bloating, fat gain, and swelling
  • Breast pain;
  • Light vaginal bleeding or spotting
  • Hair loss on the scalp

This isn't a complete list of possible side effects, and other side effects could be present. Consult your physician for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

It is sometimes not safe to take certain medications in combination. Certain drugs may affect the blood levels of the other drugs you are taking, which could cause more side effects or make the medication less effective.

Other medications can interfere with ethinyl esteradiol or norethindrone. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your doctor about the medicines you are currently taking and any medication you begin or stop taking.