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Generic name: chenodiol, also known as chenodeoxycholic acids [KEE-noe DYE-ol].
Drug class: gallstone-solubilizing agents

What is Chenodal?

Chenodal comes from bile acids, which are found naturally in our bodies.Chenodal can be used to dissolve gallstones for people who are unable to have a gallbladder operation.Chenodal can be used in other ways not mentioned in this guide.

Side effects of Chenodal

If you experience symptoms indicative of an allergic reaction, such as hives, difficulty breathing or swelling to lips, face, tongue or throat - seek medical assistance immediately!

Chenodal can cause serious side effects. If you experience:

  • Gallstones symptoms that worsen or do not improve;
  • Severe or ongoing diarrhoea;
  • Liver problems: loss of appetite, upper abdominal pain, fatigue, easy bruising, clay-coloured stool, dark urine, jaundice

Chenodal side effects may include:

  • Mild stomach cramps
  • Abnormal blood tests (lower white blood cell count, higher cholesterol, and triglycerides)

There may be other side effects. Call your doctor immediately if experiencing side effects and report them immediately at 1-800-FDA-1088 for immediate advice and reporting of adverse events.


Chenodal should not be used if you suffer from liver disease or cirrhosis.Chenodal may cause birth defects or harm to an unborn child. Use caution if pregnant.

Before you take this drug

If you have an allergy to Chenodal,

  • You are pregnant.
  • You have bile-duct obstruction or another disorder.
  • You have pancreatitis due to gallstones.
  • You have cirrhosis or another liver disease.
  • You have a blockage of your digestive system (stomach, intestines).

Tell your doctor about any liver disease or jaundice you may have had in the past.Avoid using Chenodal while pregnant. It may harm your unborn child or cause birth defects. While using this medication, use birth control to avoid pregnancy.It is unknown if chenodiol can pass into breast milk or if the baby who is nursing could be affected. Inform your doctor if breastfeeding is taking place.

How to take chenodal?

Do not exceed the prescribed dose or length of use. Take Chenodal only as prescribed. Do not exceed the prescribed dosage or duration.Take Chenodal twice a day until the gallstones have been completely removed. Please follow your doctor's advice.Chenodal should not be given beyond 2 years.Regular use of Chenodal will provide the best results. Refill your prescription before you run out.

Your symptoms may not improve for up to 12 months. Continue to take the medication according to instructions, and inform your doctor if you do not see improvement in your symptoms after six months.You may need to have frequent blood tests while using Chenodal. Your gallbladder may need to be examined with an ultrasound, x-ray, or ultrasound.Chenodal may be part of an overall treatment programme that includes weight management and a special dietary plan. Your doctor or nutritionist will have a diet plan for you. Follow it. Learn about the foods that you should avoid in order to control your condition.

Store away from heat and moisture at room temperature. Keep the bottle tightly shut when not being used.There is still a possibility that gallstones will return in 5 years, even if you have been treated. Speak to your doctor regarding your particular risk. Chenodal does not prevent gallstones.

What happens if I miss the dose?

As soon as you remember a missed dose, take it immediately. If it is close to time for another scheduled dosage, skip this missed one; additional medication should not be taken to make up for a missed one.

What happens if I overdose?

Call 1-800-222-1222 immediately if you suspect poison or seek immediate medical treatment.

What should be avoided?

Obey any restrictions that your doctor may have placed on you regarding food, beverage, or physical activity. Avoid foods high in cholesterol or fat.

Interaction with other drug

Tell your doctor if you are taking any new medications or if you will stop taking any of your current ones.

  • Cholestyramine;
  • Colestipol;
  • Hormonal replacement therapy or birth control pills
  • Antacids that contain aluminium: Almacone (Gelusil), Maalox (Mag-al Plus), Mylanta (Rulox), and others.
  • A blood thinner: warfarin Coumadin Jantoven

This list is incomplete. Other drugs, such as prescription and OTC medications, vitamins, and herbal products, may interact with chenodiol. This medication guide does not list all possible interactions.




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