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Buprenex Injection

Generic Name: Buprenorphine injection [byoo-pre-NOR-feen]
The Brand Name is: Buprenex.
Drug Class: Opiates (narcotic analgesics)

What is Buprenex?

Buprenex can be described as an opioid medication that is used to alleviate pain. Opioids are sometimes referred to as narcotics. Buprenex injections are used to alleviate mild pain that is not severe enough to warrant an opiate painkiller and for which other medications (e.g., non-opiate painkillers or opiate-containing combination drugs) are not, or will not be, sufficient.

This guide to medication provides details on what is known as the Buprenex name for buprenorphine. Sublocade is another name for buprenorphine injections that are used to treat addiction to opioids.

Warnings

The misuse of opioids can lead to addiction, overdose, or even death. Keep the medication at a distance where others can't access it. Utilizing Buprenex during pregnancy can cause withdrawal symptoms that can be life-threatening to the infant. The risk of fatal side effects could occur when you mix opioids in conjunction with alcohol or other medications that can cause drowsiness or slow the rate of breathing.

Before you take this drug

It is not recommended to use Buprenex. If you have an allergy to buprenorphine or you suffer from:

  • Serious, severe asthma or breathing issues severe asthma or breathing problems.
  • A blockage in your stomach or your intestines.

To ensure that Buprenex is suitable for you, inform your doctor if you've ever experienced:

  • Breathing issues, sleep apnea.
  • A head injury, brain tumor, or seizures.
  • Alcoholism, drug addiction, mental illness.
  • Problems with urination.
  • kidney or liver disease.
  • Heart rhythm disorders (especially when you are taking medications in order to manage them).
  • Long QT syndrome (in the case of you or a member of your family).
  • The imbalance of electrolytes (such as a low level of magnesium, potassium, or magnesium in the blood).
  • An abnormal curvature of the spine that can affect breathing.
  • Addison's Disease (adrenal gland disorder), also known as.
  • Issues with your gallbladder, pancreas, or thyroid.

If you take opioids while pregnant, your child could develop dependence on the medication. This can cause severe withdrawal symptoms for the newborn after it's born. Babies born addicted to opioids may require medical treatment for several weeks. Buprenorphine may be in the milk of a nursing baby and could harm the infant. Don't breastfeed when you are taking Buprenex.

How to take Buprenex?

Buprenex is injected into a muscle or injected as an injection into the vein. A healthcare professional will administer this injection. Buprenex is typically given as an injection only in the event that you are unable to consume the medication by mouth or if you require a different type of buprenorphine.Buprenex is typically administered at intervals that are evenly spaced, at least 6 hours apart. Inform your physician if Buprenex doesn't ease your pain in the first hour after receiving an injection.

Buprenex may result in irritation if it is placed in contact with the skin. If this occurs, you should remove the clothing the medicine spilled on and wash the skin with water. Don't share opioids with a person, especially those who have a history of substance abuse or addiction. The misuse of opioids can lead to addiction, overdose, or even death. Place the medication in a safe place so that others can't access it. Offering or selling opioids is against the law.

Details on dosage

Usual Adult Dose for Pain:

Dose for the first time: 0.3 mg of deep IM or IV slowly (over at least two minutes) You may repeat this dose after 30 to 60 minutes, if required; after that, 0.3 mg IV/IM every 6 hours, if needed.
A one-time 0.6 mg IM dose is possible for patients who aren't in the high-risk category (see the Warnings).
The single maximum dose is 0.3 mg (IV) or 0.6 mg (IM).

Usual Pediatric Dose for Pain:

From 2 to 12 years: Initial dose: 2 to 6 mg/kg in the IM or a slow IV for up to six hours.
Certain patients may not require treatment for 6–8 hours. Fixed intervals or continuous doses should not be utilized until the appropriate interval between doses has been established.
For a period of 12+ years
Dose for the first time: 0.3 mg in deep IM or in a steady IV (over at least two minutes). You may repeat this dose every 30 to 60 minutes if necessary, and then 0.3 mg IV/IM every 6 hours, as needed.
Maximum single dose: 0.3 mg
Comments: Be extra cautious when it comes to IV administration, particularly the initial dose.
Monitor closely for signs of respiratory depression, particularly between 24 and 72 hours.
Use the dose that is most effective with the shortest time frame that is compatible with the patient's specific treatment objectives.
Use: To manage the effects of pain so severe that it is deemed to warrant an opioid analgesic and for which alternative treatment options are not sufficient.

What happens if I miss a dose?

Since you'll be receiving Buprenex in a clinical setting, you're not likely to be able to miss the dose.

What happens if I overdose?

Take immediate medical attention, contact a medical professional immediately, or call the Poison Help line at 1-800-222-1222. A fatal overdose of Buprenex can cause death, especially for those who have taken the medicine without a prescription. Overdose symptoms may include extreme drowsiness, weakness, clammy or cold skin, a slow pulse, and a weak pulse. slow breathing or an induced coma.

What should be avoided?

Don't drink alcohol. Dangerous side effects or even death may occur. Avoid driving or engaging in hazardous activities until you are aware of how Buprenex can affect you. Difficulty or drowsiness may result in accidents, falls, or serious injuries.

 Side effects of Buprenex

See a doctor immediately. If you are experiencing symptoms that indicate an allergy reaction to Buprenex, such as hives, breathing problems, and swelling of your lips, face, or tongue.

Opioid medication can stop or slow breathing, and it is possible to die. The person who is caring for you must administer Naloxone or seek medical attention if you experience prolonged breathing, pauses in your breathing, blue-colored lips, or if you find it difficult to get up.

See your doctor right away. If you suffer from:

  • Loud breathing, sighing deep breathing, breath that stops when you sleep.
  • Heartbeat that is slow or weak.
  • Blue lips or fingernails.
  • Serious constipation.
  • Disorientation, extreme happiness.
  • Few or no urinations.
  • Low cortisol levels cause symptoms such as nausea, vomiting, loss of appetite, fatigue, dizziness, or weakness.

Get medical attention now if you are experiencing symptoms of serotonin disorder, for example: agitation, hallucinations, fever, sweating, shivering, high heart rate, muscle stiffness and twitching, loss of coordination, nausea, vomiting, and diarrhea. Risky side effects are more likely to occur in older patients or those who are overweight or malnourished. Weak. The long-term use of opioids could alter fertility (the ability to have children), whether in women or men. It is unclear if the effects of opioids on fertility are permanent.

Common side effects of Buprenex include:

  • Constipation.
  • Headache.
  • Dizziness, spinning sensation.
  • Nausea, vomiting.
  • An increase in sweating.
  • Drowsiness.
  • Blurred vision, double vision.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your physician to seek advice on adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

There is a possibility of breathing issues or withdrawal symptoms when you discontinue or start using certain other medications. Inform your doctor if you are also taking any antibiotic or antifungal medication. blood pressure or heart-related medications, seizure medication, or medication to treat HIV as well as Hepatitis C.

Opioid medicine may interact with other medications, causing deadly side effects or even death. Make it sure your doctor is aware if you are taking:

  • Medicine for allergies or colds, such as the bronchodilator asthma and COPD medication or diuretic ("water pill").
  • Medicines to treat motion sickness and irritable bowel syndrome medicines for motion sickness, irritable bowel syndrome, and the overactive bladder.
  • Other narcotic drugs, such as opioid pain medicine and prescription medicine for cough
  • A sedative similar to Valium: diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and many others.
  • Drugs that can make you tired or reduce your breathing A sleeping pill, a muscle relaxer, or medication to treat mental or mood disorders.
  • Serotonin-related drugs can alter the concentrations in the body. stimulant, or a medicine for Parkinson's disease, depression, migraine headaches, serious infections, nausea, and vomiting.

This list isn't complete. Other medications can be affected by buprenorphine. Pharmaceutical medications, vitamins, and herbal products. There are many possible interactions that are not mentioned here.

DRUG STATUS

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Prescription only

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