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Generic name: levoketoconazole [LEE-voe-KEE-toe-KON-a-zole]

Drug class: Adrenal corticosteroid inhibitors

What is Recorlev?

Recorlev treats high cortisol in adults who have Cushing’s syndrome but cannot undergo surgery. It is also used for those who have already had surgery and it has not cured them.Recorlev does not treat fungal infections.Recorlev can be used in other ways not mentioned in this guide.

Side effects of Recorlev

Seek immediate medical care if you have any of these symptoms: difficulty breathing, hives, swelling in your face, lips, throat, or tongue.

Recorlev may cause serious side effects. If you experience:

  • You may experience rapid or pounding pulses, shortness of breath, and sudden dizziness.
  • Liver problems: loss of appetite, pain in the upper right corner of the stomach, fatigue, itching dark urine, clay-colored stools, jaundice
  • Reduced adrenal gland hormones: nausea and vomiting; stomach pain or discomfort; fatigue; or feeling light-headed. Muscle or joint pain Skin discoloration.
  • Males: breast enlargement and erectile dysfunction (impotence);
  • Females: low desire for sex, mood changes
  • Low sodium level: leg cramps, constipation, numbness, tingling or numbness, muscle weakness, or a limp feeling.
  • If you feel faint or lightheaded, then this is a serious condition.

Recorlev side effects may include:

  • Nausea, vomiting, stomach pain, upset stomach;
  • Low potassium
  • Easy bleeding, easy bruises;
  • High blood pressure
  • Headache;
  • Abnormal uterine bleeding;
  • Redness of the skin
  • Tiredness;
  • Back pain and muscle
  • Sleep problems
  • Fluid retention;
  • Cold symptoms like a stuffy nose and sneezing.

There may be other side effects. For medical advice on side effects, call your doctor. To report adverse effects, you can contact the FDA at 1-800-FDA-1088.

Similar/related drugs

Dexamethasone, Decadron, Cyproheptadine, and Mifepristone


If you experience any of these symptoms, call your doctor immediately: swollen abdomen, upper right stomach pain, loss of appetite, dark urine or stools with a clay color, or jaundice.Recorlev may also be a cause of serious heart problems. Contact your doctor immediately if you experience rapid or pounding pulses, shortness of breath, or sudden dizziness.

Before you take this drug

Recorlev should not be used if:

  • Liver problems
  • A heart rhythm disorder,
  • Long-QT syndrome

Recorlev should not be taken with other medications that prolong QT or alter the liver's function.

Inform your doctor if you experience any of these symptoms:

  • Liver problems
  • Gallstones;
  • A heart rhythm disorder.
  • Congestive heart failure;
  • Long QT syndrome (in yourself or in a member of your family);
  • An electrolyte imbalance can occur when there is a low level of magnesium or potassium in the blood.

Can harm an unborn child.Tell your doctor immediately if you plan to get pregnant.Recorlev can affect the fertility of men or women. Recorlev can make it harder for either parent to get pregnant. Speak to your doctor about the risks.Do not breastfeed for 1 day after taking this medication.

How to take Recorlev?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label.Records can be taken with or without food.If you experience certain side effects, your treatment may be altered, delayed, or discontinued permanently.Before and during Recorlev treatment, you will need to have blood tests done to measure your liver function and blood electrolyte level.Electrocardiograms (also called EKGs) are used by doctors to check the heart's function.You will be asked to provide blood or urine samples by your doctor in order to determine the cortisol level.Keep away from moisture and heat at room temperature.

What happens if I miss the dose?

Do not take the missed dose. Use your next dose as usual. Take only one dose at a time.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.

What should be avoided?

Avoid alcohol. It can have dangerous side effects.

Interaction with other drug

Recorlev can be made harder to absorb by some medicines. Take your antacid 2 hours before taking this medicine. Tell your doctor if other stomach acid-reducing medications, such as Nexium Prevacid, Prilosec, Protonix Zantac, and others, are also being taken.It is sometimes not a good idea to take certain medications at the same time. Some drugs may affect the blood levels of drugs that you are taking, which can increase side effects and make them less effective.Recorlev may cause serious heart problems. This risk is increased if you are also taking certain other medications for asthma, heart disease, depression, mental illness, or cancer.Recorlev can be affected by many drugs. These include prescription and non-prescription medicines, vitamins, and herbal products. This list does not include all possible interactions. Tell your doctor about all medications that you take.