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Generic name: ethinyl estradiol and norgestimate [ETH-i-nil-ES-tra-DYE-ol-and-nor-JES-ti-mate]

Brand names: Estarylla, Femynor, Mili, Mono-Linyah, Nymyo,… show all 22 brands
Drug class: contraceptives

What is Estarylla?

Estarylla contains a mixture of female hormones that prevents ovulation. Estarylla can also cause changes to your cervical mucus, uterine lining, and other tissues. This makes it more difficult for fertilized eggs to adhere to the uterus.Estarylla can be used to stop pregnancy. This medicine is available in many different brands. This leaflet does not list all available brands.Estarylla can be used in other ways not mentioned in the medication guide.

Side effects of Estarylla

If you experience any of the following symptoms of an allergy reaction, seek immediate medical attention: difficulty breathing, hives, swelling in your lips, face, throat, or tongue.

Some birth control pills can cause severe side effects. Call your doctor immediately if:

  • Signs of a Stroke: sudden numbness (especially on one side), severe headache; slurred or shaky speech.
  • Signs of blood clots: sudden vision loss, chest pain that stabs, shortness of breath, blood in the cough, or pain or heat in both legs.
  • Heart attack symptoms: chest pain, pressure or pain in your shoulder or jaw, nausea, and sweating.
  • If you have liver disease, look for symptoms such as fatigue, nausea, abdominal pain, dark urine, or clay-colored stools.
  • A severe headache that pounds in the neck or ears.
  • You may experience swelling of your ankles or feet, hands, or even both.
  • Changes in migraine headaches' pattern or severity;
  • A breast lump,
  • Symptoms of depression include sleep problems, fatigue, feeling weak, and changes in mood.

Estarylla can cause a variety of side effects, including:

  • Stomach pain, gas, nausea, vomiting;
  • Breast tenderness
  • Acne is a darkening or discoloration of the facial skin.
  • Headaches, anxiety, and mood swings;
  • Contact lenses: problems with them
  • Weight changes;
  • Bleeding
  • Vaginal itching, or discharge

There may be other side effects. For medical advice on side effects, call your doctor. Report any suspected side effects by calling the FDA at 1-800-FDA-1088.

Similar/related drugs

Doxycycline, Clindamycin Topical, Topical Erythromycin, Tetracycline, Premarin, Norethindrone, and Levonorgestrel


Avoid using birth control pills while pregnant or after having a recent baby.Birth control pills should be avoided if: you are suffering from uncontrolled hypertension, heart problems, circulatory issues (especially in diabetes), liver diseases or liver cancers, migraine headaches that last for days, you're planning major surgery, you smoke, you're over 35 and you had a previous heart attack or stroke, a blood clot or jaundice due to pregnancy, birth control pills or cancers of the breasts, uterus/cervix, or vagina.Pill birth control can raise your chances of a stroke or heart attack.If you are older than 35 and smoke, it is not recommended that you take birth control pills.

Before you take this drug

Birth control pills may increase the risk of stroke or heart attack. If you suffer from high blood pressure or diabetes, have high cholesterol, or are obese, you're at an even greater risk. The risk of stroke and blood clots is greatest during the first year you take birth control pills. You are at high risk when you start taking birth control pills again after a break of 4 weeks.The older you get, the greater your chance of having a stroke or heart attack. This risk is increased by the amount you smoke. If you are older than 35 and smoke, it is not recommended that you take birth control pills.Avoid using it if pregnant. Tell your doctor immediately if you are pregnant or have missed more than two periods. Wait at least four weeks after giving birth if you've just had your baby.

If you are pregnant, or if:

  • Untreated high blood pressure or hypertension
  • Heart disease (chest discomfort, coronary artery diseases, history of stroke, or blood clots);
  • An increased risk for blood clots as a result of a blood disorder or heart disease;
  • Circulatory problems, especially if they are caused by diabetes
  • A history of cancers of the breast, uterus, or cervix, or of vaginal or ovarian origin;
  • Unusual vaginal bleeding not checked by your doctor
  • Liver disease, or cancer of the liver;
  • If you have severe headaches, especially migraines (aura, numbness, or vision changes) and are over 35, then this is a problem.
  • If you take any hepatitis C medication containing ombitasvir, paritaprevir, or ritonavir (Technivie).

If you've ever:

  • If you have heart disease, blood clots, high blood pressure, or are at risk of having them, then this is the product for you.
  • If you have high cholesterol, triglycerides, or are overweight,
  • Depression;
  • A seizure or migraine headache;
  • Thyroid hyperactivity and gallbladder diseases.
  • Liver or kidney disease
  • Jaundice due to pregnancy or birth-control pills
  • Menstrual irregularities;
  • Fibrocystic Breast Disease lumps, nodules, or abnormal mammograms

This medication can reduce the production of breast milk. Inform your doctor that you are breastfeeding.

How to take Estarylla?

Read all the instructions or guides that come with your medication and follow all the directions. Follow the directions on your prescription label.When you start taking this medication, it is possible that you will need to use a backup birth control method, like condoms with spermicide. You should follow your doctor's advice.One pill per day is recommended, but no more than one every 24 hours. Start a fresh pack of pills the next day when the old ones run out. If you don't take a pill every day, it is possible to become pregnant.Some birth control packages contain "reminder pills" to help you maintain your normal cycle. Usually, your period begins when you use these pills.You might experience bleeding during your first three months. If the bleeding persists or becomes very heavy, tell your doctor.If you have severe nausea or diarrhea, use backup birth control.You may have to temporarily stop taking this medication if you are going through major surgery or if you will need long-term rest. You should let any doctor who treats you know you're taking estradiol and levonorgestrel.You will have to see your doctor frequently if you are taking birth-control pills.Keep this medication at room temperature, away from heat and moisture.

What happens if I miss the dose?

Please read the directions that come with your medication. You are more likely to become pregnant if you miss a pill.Take two active pills the next day if you forget. Take 1 pill a day until the remainder of the package.Take two pills a day for two consecutive days if you missed two active pills back-to-back in the first or second week. Take 1 pill per dose for the remainder of your pack. After missing a pill, use a backup birth control method for at least seven days.You should throw away the entire pack if there are two missing active pills. If you started on Day 1, you can start another pack that day. You can continue taking the pill until Sunday if you started on Sunday. Throw out the remaining pills on Sunday and begin a brand new package that same day.You can throw away the entire pack if you have missed three pills consecutively in the first, second, or third week. If you started on Day 1, you should start another pack the next day. You can continue taking the pill until Sunday if you started on Sunday. Throw out the remaining pills on Sunday and begin a brand new package that same day.You may miss two or more pills during the month. Call your doctor if you have missed a period in two consecutive months. You might be pregnant.You can throw away the missed pill and continue taking one pill per day until you finish your pack.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

Avoid this

Don't smoke when taking birth-control pills, particularly if you are more than 35 years old.The birth control pill will not prevent you from sexually transmitted diseases, including HIV or Aids. The only way to prevent these diseases is by using a condom.

Interaction with other drug

There are other drugs that can affect the birth control pill, such as vitamins and herbal remedies. Birth control pills can be less effective when taking certain drugs. This may lead to pregnancy. Inform your doctor of all the medications you are taking and those that you stop or start using.



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