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Generic Name: Enoxaparin [ee-NOX-a-PAR-rin]
Names of Brands: Lovenox, Lovenox HP, Clexane, and Clexane Forte
Dosage Form: (100 mg/mL; 120 mg/0.8 mL; 150 mg/mL; 30 mg/0.3 mL; 300 mg/3 mL; 40 mg/0.4 mL; 60 mg/0.6 mL; 80 mg/0.8 mL)Injectable solution
Drug Class: Heparins

What is Enoxaparin?

Enoxaparin can be described as an anticoagulant that aids in the prevention of blood clots.Enoxaparin can be used to treat or prevent a form of blood clot known as deep vein thrombosis (DVT) that can cause blood clots to form in the lung (pulmonary embolism). The development of a DVT may occur following certain kinds of surgical procedures or in patients who are bedridden because of a long-term illness.

Enoxaparin can also be used to reduce blood vessel problems for those suffering from certain forms of angina (chest pain) or heart attacks.Enoxaparin is also employed for other purposes that are not covered in this medication guide.

Side effects of Enoxaparin

See a doctor immediately. If you are experiencing symptoms that indicate an allergy, such as itching or burning skin, difficulty breathing, and swelling of your lips, face, and throat,Get medical attention immediately in the event that you exhibit signs of a spinal blood clot: back pain and numbness, weak muscles in your legs, or loss of control over the bladder or bowel.

Enoxaparin may cause serious side effects. Contact your physician immediately. If you suffer from:

  • Unusual bleeding or bleeding that does not stop;
  • Simple bruises or red or purple spots on your skin
  • Nosebleeds, bleeding gums;
  • Abnormal vaginal bleeding, or you've got bloody urine or stool;
  • Vomiting blood or vomiting that looks like coffee grounds
  • indications of bleeding in your brain, such as sudden weakness (especially on the opposite part of your body), sudden intense headaches, issues with vision or speech,
  • Red blood cells are low (anaemia)—pale skin, fatigue, feeling lightheaded or tired, cold hands and feet.

Common negative side effects of enoxaparin include:

  • Nausea, diarrhoea;
  • Anaemia;
  • Confusion confusion
  • Bleeding, redness, pain, or irritation in the area at the site of injection.

This is not a comprehensive list of all the side effects. Other effects may also be present. Contact your doctor to seek medical advice on adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


Enoxaparin could cause a severe blood clot to the spinal cord when you are subjected to an examination of your spinal cord or spinal anaesthesia (epidural), in particular in the case of the genetic defect of a spinal deformity, a history of spinal surgery or multiple spinal taps, or when you are taking other medications that affect blood clotting, for example blood thinners and NSAIDs (ibuprofen, Advil, Aleve, and many others). The type of blood clot could result in permanent or long-lasting paralysis.

Contact emergency medical assistance. If you experience signs of a blood clot like pain or numbness in the back, weak muscles in the lower part of the body, or a loss of bladder or bowel control,

Before you Take this Drug

Do not take enoxaparin in the event that you are allergic to enoxaparin, heparin, benzyl alcohol, or pork products, or if you suffer from:

  • Uncontrolled or active bleeding uncontrolled or active bleeding
  • If you experienced a decrease in platelets found in your blood following being positive for a specific antibody when you were taking enoxaparin in the last 100 days,

Enoxaparin can cause you to bleed more frequently, particularly when you suffer from:

  • A haemorrhage that is genetic or caused by a disease
  • Hemorrhagic stroke;
  • An inflammation of the heart's lining (also known as an infection of the lining of your heart, also known as endocarditis);
  • The stomach, intestinal or colon bleeding, or an ulcer
  • Recent brain, spine, or eye procedure.

Enoxaparin may cause a severe blood clot in the spinal cord if you have a spinal tap or a spinal injection (epidural). The blood clot could cause long-term or even long-term paralysis. It is more likely to happen in the following situations:

  • If you suffer from a neck injury,
  • You have a spinal artery in place, or if a catheter was removed recently,
  • If you've had an extensive history of surgery for your spine or frequent spinal taps,
  • You have had a recent spine tap or an epidural anaesthetic.
  • If you are taking aspirin or an NSAID (nonsteroidal anti-inflammatory drug)—ibuprofen (Advil, Motrin) or naproxen (Aleve), diclofenac, indomethacin, meloxicam, and many others—
  • You are taking a medication to reduce blood clots (warfarin, Coumadin) or another medication to prevent or treat blood clots.

Speak to your doctor if you are ever diagnosed with:

  • A bleeding disorder like haemophilia;
  • The kidneys or liver illness;
  • Uncontrolled excessive blood pressure;
  • Eye problems triggered by diabetic issues;
  • A stomach ulcer
  • Low blood platelets after taking heparin.

Consult your physician to determine whether you are pregnant. If you are taking enoxaparin during pregnancy, be sure your doctor knows you are a patient with a mechanical heart valve.It is not recommended to breastfeed while taking this medication. Consult your physician regarding possible risk.

How to Take Enoxaparin?

Follow all instructions on the prescription label and review all medication guides and instruction sheets. Use the medication exactly according to your doctor's instructions.Enoxaparin is administered under the skin or in the form of an infusion into veins. The healthcare professional may instruct you to use the medication on your own.Take note of and follow the instructions for use that are included in your medication. Don't take the enoxaparin drug if you aren't familiar with the complete instructions to use it. Talk to your pharmacist or doctor if you have any concerns.

Make sure to prepare your injection when you are ready to administer it. Don't use it when the medication has changed colour or contains particles. Contact your pharmacist to inquire about a new medication.It is recommended to sit or lie down for the injection. Don't inject enoxaparin into muscles.

Your physician will inform you of the best place on your body to inject the drug enoxaparin. Make sure to inject at a different location every time you administer an injection. Make sure you don't inject in the same spot twice in one row.You'll need regular medical tests to help your doctor decide how long to treat you with enoxaparin.

If you are in need of a surgical or dental procedure, tell your dentist or surgeon that you're currently using this medicine. It is possible that you will need to stop your treatment for a short period of time.Place it in a cool, dry place free of heat and moisture.

Each single-use syringe filled with prefilled medicine is intended for a single use. Dispose of it after just one use, regardless of whether there's still medicine in it.

Following your first time using an Enoxaparin vial (bottle), it is required to make use of the medication in the next 28 days. Discard the vial after 28 days.

Use a needle or syringe just once, and then put them in a puncture-proof "sharps" container. Be sure to follow the laws of your state or city on how to dispose of the container. Be sure to keep it away from your reach for children and pets.

What Happens If I Miss a Dose?

Utilise the medicine as soon as you are able, but take a break from any missed doses if you are close to the time for the next dose. Don't take two doses at once.

What Happens If I Overdose?

Get medical attention immediately or contact the poison help line at 1-800-222-1222 for help. Overdoses may cause excessive bleeding.

What Should be Avoided?

Avoid activities that increase the chance of injury or bleeding. Make sure you take extra precautions to avoid bleeding while shaving or brushing your teeth.

Interaction with Other Drugs

Inform your doctor about the other medications you are taking and the medications you take to prevent or treat blood clots, for example:

  • Alteplase, reteplase, tenecteplase, and urokinase;
  • Heparin.

This list isn't complete. Other medications could interfere with enoxaparin, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Some interactions with drugs are not listed here. are included here.