The Web Health


Amphadase (injection)

Generic name: hyaluronidase (injection) [HYE-al-ure-ON-i-dase]
Names of brands: Amphadase, Hylenex, and Vitrase
The class of drugs: miscellaneous uncategorized agents

What is Amphadase?

Hyaluronidase can be described as an artificially designed protein that has been genetically engineered.Hyaluronidase can be used in conjunction with fluids that are injected into your body in order to combat the issue of dehydration. Hyaluronidase may also be utilised as a way to help your body absorb other medicines.Hyaluronidase also helps assist in ensuring that contrast dyes inside your body appear more clearly in certain kinds of x-rays or scans.Hyaluronidase can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Amphadase

Contact a medical professional immediately in the event that you exhibit symptoms or warning signs of an allergic reaction, such as asthma, hives, and swelling of your lips, face, and throat.

Amphadase may cause serious side effects.Should you experience:

  • Swelling in your feet, hands, or any other body part.
  • Inflammation, itching, or redness at the site where the injection was administered.

This list does not encompass every possible side effect. Other side effects could occur. Contact your doctor for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


The risk of serious drug interactions is high when certain medicines are taken in conjunction with hyaluronidase. Discuss all medications currently taken with your physician.

Prior to use this drug

You shouldn't be treated with hyaluronidase if you are sensitive to it.Your doctor might do a skin test in order to determine if you're allergic to hyaluronidase prior to taking the medication.

Certain medications can trigger unwanted or harmful effects when they are combined with the enzyme hyaluronidase. Your doctor could alter the treatment plan in the event that you use any of the following:

  • Furosemide (Lasix);
  • Phenytoin (Dilantin);
  • A sedative or an anxiety drug (such as diazepam and lorazepam, as well as alprazolam Valium, Xanax, Tranxene, Ativan, and many others);
  • Aspirin or salicylates;
  • Cortisone or ACTH (corticotropin);
  • Oestrogens;
  • An antihistamine (such as an antihistamine, such as an antihistamine, such as a cold) is an allergy

Discuss with your doctor if you are expecting.It might not be safe to breastfeed while taking this medication. Consult your physician about any potential risks.

How to take Amphadase?

Hyaluronidase is injected beneath the skin. It can also be injected into muscle or into other body tissues.A healthcare professional will administer this injection.Hyaluronidase is not a suitable injectable into veins (as an injection intravenously).

What happens if I miss the dose?

Since you'll be receiving the hyaluronidase drug in a clinical environment, you're less likely to be able to miss the dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or activities.

Interaction with other drugs

Other medications can influence hyaluronidase, like prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about the medicines you are currently taking as well as any medications you are about to start or stop taking.