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Empagliflozin

Generic Name: Empagliflozin [EM-pa-gli-FLOE-zin]
The Brand Name is Jardiance.
Dosage Format: (10 mg, 25 mg) Oral tablet
Drug Class: SGLT-2 inhibitors

What is Empagliflozin?

Empagliflozin is a combination of diet and exercise to help improve blood sugar control in adult patients with type 2 diabetes mellitus.Empagliflozin also helps reduce the risk of death from stroke, heart attack, or heart failure in people suffering from type 2 diabetes or heart disease.

Empagliflozin can also be used to reduce the chance of dying or needing to be admitted to a hospital due to heart failure when your body can't pump blood efficiently.Empagliflozin isn't used to combat type 1 diabetes.Empagliflozin is also employed for other purposes that are not covered in this guideline.

Side effects of Empagliflozin

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, such as hives, difficulty swallowing, breathing difficulties, and swelling of your lips, face, and tongue,

You should seek medical attention promptly if you are experiencing symptoms of a serious genital illness (penis or vagina): burning, itching, or stinging; odour; discharge; pain; tenderness; swelling or redness in the rectal or genital region; fever; not feeling well. The symptoms could worsen rapidly.

Stop taking the medication and contact your doctor immediately. If you suffer from:

  • A feeling of lightheadedness, as if you're passing out;
  • Dehydration--dizziness, confusion, feeling very thirsty, less urination;
  • Ketoacidosis (too much acidity in the blood) ketoacidosis (too many acids in the blood) vomiting, vomiting nausea, stomach discomfort, confusion, sleepiness, difficulty breathing,
  • Symptoms of bladder infections—pain or burning sensation when you go to the bathroom, blood in the urine, pain in your pelvis or in your back.

Certain adverse reactions are more likely to be experienced by older adults.

Common adverse effects of empagliflozin could be:

  • A bladder infection;
  • Women with yeast-related infections (vaginal discharge or itching)

This is not a comprehensive list of all the side effects. other side effects could be present. Contact your doctor to seek medical advice on the effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Warnings

Stop taking this medication and consult your physician at the earliest opportunity if you show symptoms of a serious adverse reaction like nausea, stomach pain, tiredness, or even trouble breathing.

Inform your doctor if you are suffering from vomiting or diarrhoea or if you consume less food or drink than you normally would.

Empagliflozin can lead to serious infections of the vagina or penis. Get medical help immediately if you notice burns, an itchy smell and discharge, pain or swelling, redness, tenderness of the rectal or genital region, fever, or do not feel well.

Before you Take this Drug

Empagliflozin should not be used when you have an allergy to this medication or are:

  • Chronic kidney condition (or those who are taking dialysis).

Inform your doctor if you have ever suffered from:

  • kidney disease or liver failure;
  • A bladder infection or problems with urination;
  • A sexually transmitted disease (penis or vagina);
  • Problems with your pancreas, which include the need for surgery;
  • Alcoholism or if you regularly consume large quantities of alcohol.
  • If you are following an eating plan with a low salt intake,
  • If you're 65 years old or over.

Follow the instructions of your physician regarding the use of empagliflozin when you are pregnant or are planning to become pregnant. Controlling diabetes is vital during pregnancy.

It is not recommended to take empagliflozin in the second or third trimester of pregnancy.

Do not breastfeed.

Not permitted for use by anyone less than the age of 18.

How to Take Empagliflozin?

Follow all the instructions on the prescription label and review all medication guides and instruction sheets. Your doctor may alter the dosage. Follow the medication exactly as prescribed.It is possible to take empagliflozin either along with or even without food.

Your blood sugar level will need to be monitored regularly, as well as the levels of ketones present in your urine. The ketoacidosis that is caused by empagliflozin can be life-threatening (too much acid in your blood). Even if your blood sugar level is normal, consult your physician when a urine test indicates that ketones are elevated in your urine.Blood sugar levels can be affected by illness, stress, surgery, drinking alcohol, or eating infrequently.

Low blood sugar levels (hypoglycemia) can cause you to feel thirsty, dizzy, upset, or shakey. To speedily manage hypoglycemia, consume or drink crackers, hard candy raisins, fruit juice, and non-diet drinks. Your doctor might prescribe glucagon injections if you suffer from extreme hypoglycemia.

It is possible to become dehydrated during an illness that lasts a long time. Consult your physician if you have a stomach ache or diarrhoea. Also, consume less food or drink than you normally do.This medicine may affect the outcomes of certain medical tests. Inform any physician who treats patients that you're using empagliflozin.The treatment could include exercise, diet, weight control, or specific medical treatment.Be sure to keep the temperature at room temperatures, free of moisture and heat.

Details on Dosage

Usual Adult Dose for Diabetes Type 2:

10 mg orally, once a day, beginning in the early morning
For additional control of glycemic levels, patients who are tolerant to this medication may increase dosage up to 25 mg taken orally every day.
Uses:
To reduce the chance of dying from cardiovascular causes in patients suffering from the type 2 form of diabetes as well as existing cardiovascular disease
as an aid to exercise and diet to increase glycemic control for those suffering from type 2 diabetes mellitus.

Usual Adult Dose for Cardiovascular Risk Reduction:

10 mg oral, taken once every day in the in the morning
For further glycemic control, patients who are tolerant to this medication may increase dosage up to 25 mg taken orally every day.
Uses:
To decrease the risk of death from cardiovascular disease for patients with type 2 diabetes mellitus as well as existing cardiovascular disease
as a supplement to exercise and diet to increase glycemic control in patients suffering from type 2 diabetes mellitus.

Usual Adult Dose for Heart Failure:

10 mg orally, once a day, in the morning
Use: To decrease the risk of death from cardiovascular causes and hospitalisation due to heart failure among patients suffering from heart failure.

What Happens If I Miss a Dose?

Do not take the medicine for as long as you can. However, avoid any missed doses if you are nearing the time to take the next dose. Don't take two doses at a time.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Do not drink alcohol.

Be careful not to get up too quickly from a lying or sitting position, as you could be dizzy.

Interaction with Other Drugs

Other medications can alter or enhance their effects, decreasing your blood sugar. Inform your doctor of all the medicines you are currently taking and all those you are about to start or stop using, in particular:

  • Insulin or any other oral diabetes medicines
  • Diuretic, also known as a "water pill."

This list isn't complete. Other medications can affect empagliflozin. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions between drugs. are included here.