What is Durezol?
Durezol is a corticosteroid medication. It stops the release of substances that cause inflammation in the body. Durezol ophthalmic gel is used to relieve eye inflammation and pain caused by surgery. Durezol can also be used to treat anterior veitis, inflammation of the front portion of the eye.
Warnings
Durezol should not be used if you are untreated for glaucoma or any other eye infection, including herpes. The tip of the dropper should not touch anything, including your hands or eyes. The dropper could become contaminated and cause an infection, which may lead to serious eye damage or vision loss. Durezol is not to be used with regular contact lenses. After using eye drops, wait at least 10 minutes before inserting lenses. Wear only contact lenses that have been prescribed by your doctor. If your symptoms don't improve after two days, talk to your doctor. Durezol should not be stopped without consulting your doctor. It may be necessary to reduce the dosage before stopping completely. Durezol can cause blurred vision, and it may affect your ability to think or react. Care must be taken when driving or performing any task which necessitates alertness and an ability to see clearly, such as cooking or using tools that require clear vision.
If you experience sudden irritation or pain in your eyes, severe redness, itching, or swelling, pain behind the eye, sudden changes in vision, severe headaches, slow healing following eye surgery, signs (swelling or crusting), or new symptoms of infection (swelling or drainage), or if your vision is blurred, you see halos around lights or have tunnel vision.
Before you take this drug
Durezol should not be used if you're allergic to difluprednate or have any kind of eye infection (including herpes) caused by bacteria, fungi, or viruses.
Tell your doctor about any of the following to ensure that Durezol will be safe for you:
- Glaucoma;
Difluprednate is not known to harm an unborn child. Inform your doctor if you are pregnant. Breast-feeding may not be possible while on this medication. You should consult your doctor if you are concerned about any risks.
How to take Durezol?
Durezol ophthalmic gel should be used exactly as directed by your doctor. Read all the instructions on the prescription label. This medicine may be prescribed by your doctor in two separate bottles, one for each eye. To prevent infection spreading from one eye into the other, this is done. Mark each bottle with the left or right eye, and only use eye drops from the bottle in that eye.
How to apply Durezol eyedrops:
- Before using eye drops, wash your hands.
- To create a pocket, tilt your head slightly back and pull your lower eyelid down.Squeeze out some drops by looking up and away while pressing down with the dropper tip.
- Close your eyes without blinking, squinting, or moving your head. For about 1 minute, gently press your finger on the inside corner of your eye to prevent the liquid from draining.
- Only use the drops prescribed by your doctor. Wait 5 minutes in between drops if you are using more than one.
- You should wait at least 10 minutes after using the eye drops prescribed by your doctor before you use any other eyedrops.
Avoid touching the tip or placing it directly on your eye.Contamination can pose severe vision impairment issues.This medicine should not be used while wearing soft lenses. Durezol's ophthalmic solution may contain a chemical preservative, which can cause soft contact lenses to discolor. Wait at least 10 minutes after using the medicine before inserting your contact lenses. Wear only contact lenses that have been prescribed by your doctor. If your symptoms don't improve after two days of treatment, consult your healthcare provider immediately.Durezol can cause pressure in the eyes to increase if you use it for more than 10 days. You may need frequent eye tests to monitor this. Store at room temperature, away from moisture and heat. When not in use, keep bottle tightly sealed to avoid leakage or moisture absorption. Do not abruptly discontinue taking this medication without first consulting with a physician about dosage instructions.
Details on dosage
Adult Durezol Dose Typical for Postoperative Ocular Inflammation:
After surgery, instill one drop of conjunctival solution into the eye's sac four times a day. This should continue for the first two weeks. Then reduce to 2 drops per day and taper off based on response.
Use: To treat inflammation and pain after ocular surgery.
Adult dose of Durezol:
Drop 1 drop in the conjunctival sac four times a day for 14 consecutive days, then taper off as indicated by the clinical indication.
Use: Treatment for Endogenous Anterior Uveitis
The usual pediatric dose of durezol to treat postoperative ocular inflammation is:After surgery, instill one drop of conjunctival solution into the eye's sac four times a day. This should continue for the first two weeks. Then reduce to 2 drops per day and taper off based on response.
Use: To treat inflammation and pain after ocular surgery.
The usual pediatric dose of Durezol to treat uveitis in children is:
Drop 1 drop in the conjunctival sac four times a day for 14 consecutive days, then taper off as indicated by the clinical indication.
Use: Treatment for Endogenous Anterior Uveitis
What happens if I miss the dose?
If you are almost due for your next dose, skip the missed dose. Never take two doses of the same medicine at once.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Durezol can cause blurred vision or affect your reaction. Do not drive or engage in hazardous activities until you have determined how Durezol will affect you. This medicine should not be shared with anyone else, even if the other person has similar symptoms.
Side effects of Durezol
If you experience any of the following symptoms of an allergic reaction: hives, difficulty breathing, swelling of your lips, face, tongue, or throat, or hives, seek emergency medical attention.
If you experience:
- Pain behind your eyes, sudden vision changes;
- Slow healing after eye surgery
- Eye pain, tunnel vision, or seeing halos around light
- Signs of a new eye infection include swelling, drainage, or crusting.
Durezol may cause side effects such as:
- Eye itching or irritation
- Blurred vision
- Watery eyes
- Headache;
- Feeling like there is something in your eye
- Your eyes may be more sensitive.
There may be other side effects. Call your physician immediately if experiencing side effects; to report adverse events directly with FDA please call: 1-800-FDA-1088
Interaction with other drug
Other drugs you take shouldn't alter the medication used on your eyes.Many drugs interact with each other. Inform your healthcare provider about the medicines you take, including over-the-counter and prescription medicines, vitamins, and herbal products.
