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Canasa Pac (rectal)

Brand names: Canasa Pac, Rowasa SF, mesalamine (rectal).
Drug Class: 5-aminosalicylates

What is Canasa Pac (rectal)?

Canasa is used for the treatment of ulcerative colitis and proctitis in adults. Canasa Pac can be used in other ways not mentioned in this guide.

Side effects of Canasa Pac (rectal)

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat.

Canasa Pac may cause serious side effects. If you experience:

  • Severe stomach pain, cramping, and bloody diarrhoea;
  • Fever; headache;
  • Rash, itching, and eye redness;
  • Low white blood cell count—fever and chills; sore neck; cough. Feeling light-headed.
  • Signs of kidney stones: severe back and side pain, frequent urination, urine with a foul smell, or urine that is cloudy or dark;
  • Kidney problems: increased or decreased urination; swelling; weight gain.

In older adults, a lower white blood cell count is more common.

Canasa Pac can cause the following side effects:

  • Fever;
  • Dizziness;
  • Colitis and rectal pain
  • Rash;

There may be other side effects.Call your physician if experiencing side effects; otherwise call the FDA's National Hotline: 1-800-FDA-1088 to report them.

Similar/related drugs

Hydrocortisone, mesalamine, Lialda, Cortef, Pentasa, and Apriso

Warnings

If you experience severe stomach pain, cramps, or bloody diarrhoea, call your doctor immediately.

Before you take this drug

Canasa Pac should not be used if you have an allergy to Canasa Pac or any of its ingredients (such as aspirin, Doans Pills, Dolobid Kaopectate, Nuprin Backache, Pepto-Bismol Tricosal Trilisate, and others).

Inform your physician of any of the following issues:

  • A skin condition such as eczema;
  • A kidney stone or kidney disorder;
  • Asthma, or allergy to sulfite
  • Liver disease.

Tell your doctor about any diarrhoea you observe in the baby if you are nursing.

How to take Canasa Pac (rectal)?

Carefully read all instructions or guides included with your medication and follow all label directions exactly. Follow the directions on the label. Avoid taking a rectal supppository or enema with your mouth. Use it only on your rectum.

For best results, use Canasa Pac at bedtime. Before using rectal medication, try to empty your bladder and bowel. Please read and follow all instructions for use that come with your medicine. Use rectal medication only after washing your hands.

Remove the wrapping before inserting the suppository. Do not handle the suppository for too long, or it may melt. Lay on your back, with your knees pointing up towards your chest. Insert the suppository gently into your rectum, pointing the tip first.

You can lie down and let the suppository dissolve for a few moments. There should be little to no discomfort. If possible, avoid using the toilet for at least 1 to 3 hours. Be sure to shake the liquid rectal well before using. Canasa Pac is a great way to stay hydrated.

For the enema, lie on your left with your left leg straightened and your right leg slightly bent. Remove the cap and gently insert the tip into the rectum. Slowly squeeze the bottle until the entire contents are emptied into your rectum.

Lay on your left for 30 minutes after using an enema to allow liquid to spread throughout your intestines. Hold the enema for at least eight hours, or even all night if you can. Every day, drink plenty of water.

Your symptoms may not improve for up to three weeks. Continue to take the medication according to instructions, and inform your doctor if you do not see improvement in your symptoms.

Blood tests may be required to monitor your kidney or blood cell function. Canasa Pac can interfere with certain medical tests. You should tell any doctor that treats you about Canasa Pac.

Store away from moisture, heat, and cold at a cool temperature. After removing the foil pouch, it is possible that the enema fluid will darken. The medicine should not be affected by this. Throw away any enema fluid that has become dark brown.

What happens if I miss the dose?

Wait until the next time you go to bed before taking the missed dose. Do not take two doses of the medicine at once.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Avoid applying Canasa Pac to clothing, flooring surfaces, painted surfaces, vinyl surfaces, marble, granite, and other surfaces. Canasa Pac products may stain surfaces.

Canasa Pac can make you burn easier if you suffer from eczema. Avoid tanning beds or sunlight. When you're outdoors, wear protective clothing and use sunblock (SPF 30 or higher).

Interaction with other drug

Canasa Pac may harm your kidneys if you are also taking certain medications for cancer, infection, osteoporosis, or organ rejection. Other drugs that can cause kidney damage include Advil, Motrin, and Aleve.

Tell your doctor if you are taking any other medications, including:

  • Azathioprine or 6-mercaptopurine;

This list is incomplete. Canasa Pac may be affected by other drugs, such as prescription and over-the-counter medicines and vitamin and herb products. This list does not include all possible drug interactions.