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Generic Name: Mesalamine Oral [mee-SAL-ah-meen]
Drug Class: 5-aminosalicylates

What is Lialda?

Lialda is a drug that affects a substance within the body that causes tissue damage, inflammation, and diarrhoea.Lialda treats mild to moderate active colitis ulcerative in children and adults who weigh at least 24kg.Lialda can also be used as a maintenance therapy in adults to prevent the symptoms associated with ulcerative colitis from recurring.


If you experience severe stomach pain or cramping and bloody diarrhoea, stop using Lialda immediately and contact your doctor. This may also occur with a fever, headache, or rash.

Before you take this drug

Lialda should not be used if you have an allergy to salicylates, aspirin, or mesalamine (such as Disalcid). Doans Pills. Dolobid. Kaopectate. Nuprin Backache. Pepto-Bismol. Tricosal. Trilisate.

Tell your doctor about any of the following to ensure that Lialda will be safe for you:

  • A kidney stone or kidney disorder;
  • Liver disease
  • A blockage of your stomach or intestines, such as pyloric obstruction;
  • A skin condition such as eczema.

If you are planning to become pregnant, inform your doctor as soon as possible. Mesalamine can harm an unborn child, but this is unknown. Untreated or uncontrolled colitis can cause pregnancy complications, such as low birthweight or premature birth. It is possible that the benefits of treating ulcerative bowel disease outweigh the risks for your baby.Lialda may make it unsafe to breastfeed. You should consult your doctor if you are concerned about the risk. Tell your doctor about any diarrhoea you observe in your nursing child if you are breastfeeding.

How to take Lialda?

Read all instructions and directions that come with your medication. Take the time to read the entire prescription label.Lialda can interfere with certain medical tests. Lialda can affect the results of certain medical tests.Lialda is best taken with food.Avoid kidney stones by drinking plenty of fluids.Do not chew or crush the Lialda tablets. Tell your doctor if you have difficulty swallowing.If your symptoms of ulcerative colitis do not improve or worsen, call your doctor.Lialda can interfere with certain medical tests. Lialda can affect the results of certain medical tests.Blood tests may be required to monitor your kidney or blood cell function.Keep away from moisture and heat at room temperature.

Details on dosage

Adult dose of Lialda—Active:

Tablets 1200 mg: Orally, take 2.4–4.8 g (two to four tablets) once daily with food.

Adult dose of Lialda: Maintenance:

Tablets 1200 mg: Orally, take 2.4g (two tablets) once per day.

Lialda dosage for children: active

Weight of the patient: 24 kg to 35 kg: two 1.2g tablets daily from week 0 until week 8. After week 8, take one 1.2-gramme tablet daily.
From week 0 until week 8, take three 1.2-gramme tablets daily. After week 8, take two 1.2-gramme tablets once daily.
From week 0 until week 8, take four 1.2-gramme tablets daily. After week 8, take two 1.2-gramme tablets daily.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.

What should be avoided?

Mesalamine can make you more susceptible to sunburn if you suffer from eczema. Avoid tanning beds or sunlight. When you're outdoors, wear protective clothing and apply sunscreen (SPF 30) or higher.

Side effects of Lialda

If you experience any of the following: hives, difficulty breathing, swelling of your lips, face, tongue, or throat, please seek emergency medical attention.

If you experience:

  • Severe stomach pain, stomach cramping, and bloody diarrhoea;
  • Fever, headaches, and general malaise
  • Redness of the eye
  • Bloody or tarry stool, vomiting blood, or vomit that looks like coffee grounds
  • Sore throat, feeling lightheaded, difficulty breathing, feeling feverish, low counts of white blood cells;
  • Signs of a kidney stone: severe pain on your side or back; frequent urination; foul-smelling urine; and dark, cloudy, or dark-coloured urine.
  • Kidney disease: increased or decreased urination; swelling; weight gain
  • Liver problem: upper stomach pains, fatigue, easy bruising, clay-coloured stool, dark urine jaundice (yellowing skin or eyes).

In older adults, a lower white blood cell count is more common.

Lialda may cause the following side effects:

  • Burping, constipation, nausea, vomiting, stomach pain, diarrhoea, gas;
  • Dizziness;
  • Cold symptoms like stuffy noses, sneezing, and sore throats;
  • Backache
  • Headache;
  • Rash;
  • Abnormal liver function tests

There may be other side effects. Call your doctor for medical advice about side effects. To report adverse effects, you can contact the fda at 1-800-fda-1088.

What other drugs can affect lialda?

Mesalamine may harm your kidneys if you are also taking certain medications for cancer, osteoporosis, or organ rejection. It can also be harmful if you have bowel disorders or high blood pressure.

Tell your doctor about your other medications, including:

  • Azathioprine or 6-mercaptopurine.

This list is incomplete. There are other drugs that may interact with mesalamine.Included are prescription, over-the counter, herbal, and vitamin products. This list does not include all drug interactions.




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