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Abecma

Genric Name: Idecabtagene vicleucel

Dosage: Suspension to be used for intravenous infusions

Drug Classification: Miscellaneous antineoplastics

What is Abecma?

Abecma is used for the treatment of myeloma patients who have tried at least four different treatment strategies that haven't been effective or stopped working. Abecma is a medication that is made from the white blood cells of your body. The cells have been genetically altered to detect and fight the multiple myeloma cells.

Warnings

Abecma could cause side effects that can be life-threatening and could lead to the death of a patient. Contact your doctor or seek emergency assistance right away if you suffer from any of the following symptoms:

  • Trouble breathing

  • Febrile (100.4 °F/38 °C or more)

  • Chills/shivering

  • Confusion

  • Dizziness, lightheadedness, or dizziness

  • Shaking or twitching (tremor)

  • Heartbeats that are irregular or fast

  • Serious fatigue

  • Severe nausea, vomiting, and diarrhoea

It is crucial to inform your healthcare providers that you received Abecma, and you should show them your card for your wallet. The healthcare professional may prescribe the patient other medications for any negative side effects.

How to Take Abecma?

Abecma is created from the white blood cells of your body, so your blood can be gathered by a process that is known as "leukapheresis."

The blood cells you receive are sent to a factory for the production of your adenoma. Based on research findings from clinical trials, the process takes approximately four weeks to wait until your cells arrive from the facility where they are manufactured and can be delivered back to your doctor. However, the timing may differ.

When you are scheduled for the treatment, your physician will prescribe chemotherapy for three days in order to help prepare your body.

Once your treatment is complete and your doctor is satisfied, they will administer your Abecma to you via the catheter (tube) put inside the vein (intravenous infusion). The dose could be administered via one or more bags. The typical infusion time is approximately 30 minutes for each bag of infusion.

Your health will be closely monitored by the healthcare facility that is certified by a medical professional that you were treated at every day for a minimum of seven days following the injection.

It is recommended to remain in the vicinity of 2 hours drive for at least four weeks after you have received treatment. Your doctor will be able to provide evidence that your treatment is effective and assist the patient with any negative side effects that could be experienced.

  • Avoid driving, operating large machinery, or engaging in any other activity that is hazardous if you're unmindful for at least 8 weeks after receiving treatment. The reason for this is that the treatment may cause temporary problems with coordination and memory. insomnia, sleepiness, nausea, dizziness, and seizures

  • Don't give tissues, organs, blood, or any other cells for transplantation.

Side Effects of Abecma

Most commonly, reactions are:

  • Fatigue

  • Febrile (100.4 °F/38 °C or more)

  • Chills/shivering

  • Extreme nausea or diarrhoea

  • Diminished appetite

  • Migraine

  • Dizziness/lightheadedness

  • The confusion

  • Trouble speaking or having slurred speech

  • Cough

  • Trouble breathing

  • Heartbeats that are irregular or fast

Abecma may cause a frequent side effect, a condition known as cytokine release syndrome, or CRS, that can be serious or even fatal. The symptoms of CRS are fever, breathing difficulties, and dizziness or lightheadedness. headache, nausea, fast pulse, low blood pressure, and fatigue. Inform your doctor immediately if you experience symptoms of fever or other signs after treatments.

Abecma increases the chance of developing life-threatening illnesses that could cause the death of a patient. Inform your doctor promptly if you experience symptoms of chills, fever, or any other sign or symptom of illness.

Abecma may reduce some or all of your blood cells (red blood cells, white blood cells, or platelets) and can make you tired or weak or increase your chance of bleeding or an infection that is severe. Following the treatment, your doctor will examine your blood samples to detect its presence. Inform your doctor immediately if you notice a fever, feel fatigued, or have bruises or bleeding.

If you have Abecma present in your blood, it could result in a false-positive human immunodeficiency virus (HIV) result from commercial testing.

There are many potential consequences. Contact your doctor for advice from a medical professional regarding adverse consequences. The best way to report adverse reactions is to call the FDA at 1-800-FDA-1088.

Interaction with Other Drugs

Other medicines can interfere with idecabtagene vicleucel, which includes prescription or over-the-counter medications, vitamins, and natural products. Discuss with your doctor the medicines you are currently taking as well as any medication you begin or stop taking.

 

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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