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Apraclonidine ophthalmic

Generic name: apraclonidine ophthalmic [A-pra-KLON-i-deen-off-THAL-mik]
Brand name: Iopidine
Form of Dosage: ophthalmic solution (0.5 percent (1%; 0.5 0.5%; 1))
Classification of drugs: Ophthalmic glaucoma agents

What is Apraclonidine ophthalmic?

Apraclonidine lowers the volume of fluid inside the eye, which reduces pressure in the eye.Apraclonidine ophthalmic (for the eye) is used in short-term terms to treat or reduce excessive pressure in the eye.Apraclonidine ophthalmic can be used for different reasons that are not covered in this drug guide.Side effects of Apraclonidine ophthalmicContact a medical professional immediately. If you are experiencing symptoms or warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, and tongue,

Apraclonidine ophthalmic can cause severe adverse effects. Contact your doctor immediately if you suffer from:

  • Intense itching, redness, severe itching, or irritation around your eyes;
  • The appearance of crusts or drainage around your eyes;
  • Eye pain, or increased eye watering,
  • The sensation of something being there.

Common adverse effects of apraclonidine eye drops could include:

  • Blurred vision
  • Dry eyes;
  • Eye redness or puffy, watery eyelids;
  • Dizziness, drowsiness,
  • Dry mouth.

This isn't an exhaustive list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on adverse effects. Please call the FDA's 24-Hour Hotline on 1800FDA-1088 with any possible adverse events or side effects that have arisen, on any account, at 1-800-FDA-1088 for help and report them immediately.

Similar or related drugs

acetazolamide, pilocarpine, an ophthalmic drug, Combigan, Diamox, Methazolamide, Mitomycin Eye Drops, and Ilevro


Do not take apraclonidine ophthalmic in the event that you've used an MAO inhibitor within the last 14 days, including isocarboxazid or linezolid, blue injection, or phenelzine rasagiline, selegiline, and tranylcypromine.

Before you take this drug

This medicine is for you if you're allergic to apraclonidine or the chemical clonidine (Catapres).Avoid using apraclonidine eye drops in the event that you've used an MAO inhibitor within the last 14 days. A potentially dangerous interaction with a drug could occur. MAO inhibitors include isocarboxazid linezolid, Methylene blue injection rasagiline, phenelzine, tranylcypromine, and many others.

To ensure that this medication is suitable for you, inform your doctor if you have previously had:

  • Kidney disease;
  • The liver condition;
  • Heart disease, stroke, and stroke are all examples of cardiovascular disease.
  • Coronary arterial condition (clogged arteries);
  • Peripheral vascular disorder like raynaud's syndrome or buerger's disease;
  • High blood pressure;
  • Diabetes
  • Depression.

It isn't known if this medication will cause harm to a baby who is not yet born. Consult your physician if you are expecting.It isn't known if Apraclonidine ophthalmic is absorbed into breast milk or whether it is harmful to the nursing infant. Do not breastfeed on the day that you are taking this medication.

How to take Apraclonidine Ophthalmic?

Follow the directions on the prescription label. Do not take apraclonidine ophthalmic in smaller or larger quantities or for longer periods than recommended.Apraclonidine eye drops are typically given in the form of 1 or 2 drops per affected eye, three times daily. Follow your doctor's instructions for dosing extremely carefully.Cleanse your hands prior to using drop drops for your eyes.

To apply eye drops:

  • Turn your head slightly back and pull the lower eyelid, creating small pockets. Keep the dropper over your eye with the tips downwards. Keep your eyes upwards, to the side away from where you are holding it, and squeeze the drop.
  • You can close your eyes for two or three minutes with your head down without blinking or squinting. Make sure to gently press your finger on the inner corner of the eye for around one minute to stop the liquid from escaping into the tear duct.
  • Make sure you only use the drops prescribed by your doctor.
  • Take at least 5 minutes before applying the other drops for your eyes that your medical professional has advised you to use.

Do not touch the edge of the dropper for your eyes or put them directly in your eyes. Drops that are contaminated can affect your eyes and could result in severe vision issues.Don't use eye drops if the solution is changing colour or has particles within it. Contact your pharmacist to inquire about a new medication.Apraclonidine could be less effective with time. This drug is meant for short-term use only.To ensure that this medication helps your condition, your eyesight might require testing. It is possible that you will not see any changes in your symptoms. However, vision tests can assist your doctor in determining the duration of treatment with apraclonidine.Keep it at room temperature, free of heat and moisture. Don't freeze. Make sure the bottle is tightly sealed when not being used.

Details on dosage

Usual Adult Dose for Glaucoma:

0.5 percent solution One to two drops of solution are instilled within the affected eye(s) three times per day.
When used in conjunction with other ophthalmic medications An approximate 5-minute interval between each drug should be observed in order to avoid the washing out of the previous dose.
This drug's use may not reduce the IOP when the drug is added to an existing regimen with two other medications as part of the most well-tolerated medical therapy.
Patients receiving maximally tolerated medical therapy that is used in order to defer surgery must undergo regular exams, and follow-up treatments should be stopped if the IOP increases in a significant way.
Utilisation: A short-term, adjunctive therapy for patients who are receiving the highest level of medical tolerance and who require further IOP reduction.

Usual Adult Dose for Increased Intraocular Pressure after Surgery: Usually 200 to 250 micrograms (1 mg).

1.1% Ophthalmic Solution One drop is instilled into the eye that is scheduled for operation one hour prior to the procedure beginning in the anterior segment. Then, one drop should be infused into the eye of the patient immediately following the completion of the laser surgical procedure.
Comment A separate container must be used for each dose, and you must get rid of it after each use.
Use: To prevent or control post-surgical elevations of IOP, which can be seen in patients who have undergone the argon laser trabeculoplasty procedure, argon laser iridotomy, or even neodymium-doped yttrium-aluminium garnet (Nd:YAG) posterior capsulotomy.

What happens if I miss the dose?

Take the missed dose when you remember. Do not take your missed dose if you are close to the time of the next dose. Don't use any extra medication to make up for the missed dose.

What happens if I overdose?

An accidental overdose of apraclonidine should not be thought to be risky. You should seek medical attention in an emergency or contact the Poison Help Line at 1-800-222-1222 in the event that someone has swallowed the drug accidentally.

What should be avoided?

Apraclonidine ophthalmic can impair your ability to think or react. Be aware if you are driving or engaging in any activity that requires that you be aware.

Interaction with other drug

Utilising this medication while you're taking other medications that cause sleepiness can make you more sleepy. Consult your physician before taking Apraclonidine if you're also taking sleeping pills, narcotic pain medicine, muscle relaxers, or other medications to treat anxiety, depression, or seizures.

Discuss with your physician all the medicines you are currently taking and any new medications you begin or stop taking, particularly:

  • Treatment for mental illness
  • Insulin, or oral diabetes medicine;
  • Medications for blood pressure
  • Heart rhythm medication

This list is not comprehensive. Other medications may be incompatible with apraclonidine, such as prescription and over-the-counter drugs, vitamins, and herbal products. The interactions of all potential drugs are included in this guide to medication.