The Web Health



Genric Name: bupropion hydrobromide extended-release tablets
Drug class: miscellaneous antidepressants

What is Aplenzin?

Aplenzin can be described as an antidepressant medicine that is used in treating major depression as well as seasonal affective disorder.Aplenzin is also employed for other purposes that are not covered in this guide to medication.


It is not advised to use Aplenzin when you suffer from seizures, eating disorders, or if you've abruptly stopped drinking medications for seizures, alcohol, or sedatives. If you are taking Aplenzin to treat depression, do not use Zyban to stop smoking.Do not take bupropion if you've used an MAO inhibitor within the last 14 days. A risky drug interaction may occur. MAO inhibitors are isocarboxazid linezolid, Methylene blue injection rasagiline, phenelzine, and tranylcypromine.Aplenzin is known to cause seizures, especially for those with medical conditions that are specific to them or who are taking certain medications. Discuss with your doctor all your medical conditions and the drugs you are taking.Many young people are concerned about suicide while using an antidepressant. Your doctor should monitor your progress on regularly scheduled visits while taking Aplenzin. Your family members and other carers should be aware of changes in your symptoms or mood.If you notice any new or deteriorating symptoms, report them to your physician, for example, a change in your mood or behaviour, panic attacks, anxiety, or trouble sleeping. Also, the feeling of being angry, irritable, or impulsive and aggressive, active, restless (mentally as well as physically), or more depressed, or contemplating suicide or harming yourself.

Before you take this drug

Don't use Aplenzin in the event that you've taken an MAO inhibitor within the last 14 days. A risky drug interaction may occur. MAO inhibitors are isocarboxazid linezolid, methylene blue injection rasagiline, phenelzine, and tranylcypromine, among others.

It is not recommended to use Aplenzin. If you have an allergy to bupropion or suffer from:

  • A seizure disorder;
  • Anorexia and bulimia
    if you recently stopped using alcohol, seizure medications, or serotonin (such as xanax, valium, fiorinal, klonopin, and others),

Do not take an MAO inhibitor for 14 days prior to or 14 days after taking bupropion. A dangerous drug interaction may occur. MAO inhibitors are isocarboxazid rasagiline, linezolid, phenelzine selegiline, tranylcypromine, andDo not use Aplenzin for more than one disease at one time. If you are taking Aplenzin to treat depression, do not take Zyban to stop smoking.Aplenzin could trigger seizures, particularly if you have medical conditions that are specific to you or take certain drugs. Inform your doctor of the medical conditions you suffer from and the medications you take.

To be sure Aplenzin is safe for you, ask your physician if you've previously had:

Many young people are concerned about suicide while using an antidepressant. Your doctor should monitor your progress on regularly scheduled visits while taking Aplenzin. Family members or other carers should be on the lookout for changes in your symptoms or mood.Talk to your doctor about Aplenzin in case you are expecting It is not yet known if bupropion harms the unborn child. But it is possible to experience the possibility of a relapse in depression if you discontinue the antidepressant you are taking. Contact your doctor immediately when you find yourself pregnant. Don't begin taking Aplenzin without your doctor's guidance.If you're expecting and you are a registered mother, your name could be included on the registry for pregnancy to monitor how bupropion affects you and your baby.It is not recommended to breastfeed while taking this medication. Discuss any risks or potential hazards with your physician.Bupropion has not been approved for use by anyone less than 18 years old.

Similar/related drugs

Sertraline, Trazadone, Lexapro, Citalopram, Zoloft, Cymbalta, and Wellbutrin

How to take Aplenzin?

Use Aplenzin exactly as directed by your physician. Follow all the instructions on the prescription label. Don't take this medicine in smaller or larger quantities or for longer than prescribed. A high dose of this medication may increase the chance of having a seizure.Don't crush, chew, or break an extended-release Aplenzin tablet. Suck the tablet completely.You shouldn't alter the dosage or stop taking Aplenzin abruptly unless you experience seizures while taking the medication. The abrupt stoppage of Aplenzin can trigger unpleasant withdrawal symptoms.Don't stop taking Aplenzin abruptly, or you may experience uncomfortable withdrawal effects. Consult your physician about how to effectively stop taking bupropion.Certain people who take Aplenzin have experienced high blood pressure that was extreme, particularly when taking a nicotine replacement drug (patch or chewing gum). Your blood pressure could require checking prior to and during the treatment with bupropion.This medication can result in an inaccurate positive test for drug screening. If you give a urine sample for drug screening, be sure to inform the lab personnel of the bupropion medication you're using.Place it in a cool, dry place free of heat and moisture.

What happens if I miss the dose?

You should take the missed dose as soon as you can remember. Avoid any missed doses if you are close to the time of your next dose. Do not double up on medication to make up for missed dosage.

What happens if I overdose?

Get medical attention immediately, or dial the Poison Help Line at 1-800-222-1222. A bupropion overdose could be fatal. Overdose symptoms may include muscle stiffness, hallucinations, unsteady or fast heartbeats, deep breathing, or fainting.

What should be avoided?

Drinking alcohol with bupropion can increase the risk of having seizures. If you regularly drink alcohol, discuss with your doctor before reducing the amount of alcohol you consume. Aplenzin is also known to cause seizures in those who consume a lot of alcohol, only to suddenly stop drinking once they have started taking the drug.Aplenzin could affect your ability to think or react. Be mindful when driving or engaging in any task that requires awareness.

Side effects of Aplenzin

See a doctor immediately. If you experience any of the following symptoms warnings of an allergic reaction, Aplenzin: hives, itching and fever, swelling of the glands, difficulty breathing, swelling of your throat or face) or a severe skin reaction (fever and throat soreness, eye burning, irritation, and red or purple skin rash, blisters, and flaking).Do not hesitate to report any new or increased symptoms to your physician, including changes in your mood or behaviour such as depression, anxiety, or panic attacks, difficulty sleeping, or when you are irritable, angry, or agitated. You may also feel hostile, angry, anxious, restless, overly active (mentally and physically), or more depressed, or you may be contemplating suicide or harming yourself.

Contact your doctor immediately. If you suffer from:

  • A seizure (convulsions);
  • Unusual changes in behaviour or mood
  • Blurred vision eyestrain, swelling, or seeing a lot of the lights
  • Irregular or fast heartbeats; or
  • A manic episode of racing thoughts, more energy-intensive behaviour, feeling very happy or angry, speaking much more frequently than you normally do—serious issues with sleep

Common aplenzin side effects may include:

  • Dry mouth, sore throat, congestion of the nose;
  • Ears ringing;
  • Blurred vision
  • Nausea, stomach pain, vomiting, constipation, loss of appetite;
  • Sleep problems (insomnia);
  • Feeling sweaty, having tremors, being nervous, or being anxious
  • Fast heartbeats;
  • Confusion, agitation, and hostility;
  • Rash;
  • Weight loss;
  • More frequent urination;
  • Headache, dizziness, or
  • Joint or muscle discomfort.

This is not a comprehensive list of possible side effects, and other effects may also be present. Consult your physician to seek medical advice on the effects. Report any adverse side effects directly to the FDA by calling them at 1-800-FDA-1088.

What other drugs can have an effect on Aplenzin?

There is an increased risk of having seizures if you are taking certain other medications while taking Aplenzin.A variety of drugs can be incompatible with bupropion. Discuss with your doctor the medicines you take as well as the medicines you take or stop using in the course of medication with Aplenzin. This includes both over-the-counter and prescription supplements, vitamins, and herbal products. Not all interactions are covered in this drug guide.




Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories