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Addyi

[Generical name: flibanserin] flib-AN-ser-in flib-AN’ser-in“flib-AN-ser”
Drug class: Miscellaneous central nervous system agents

What is Addyi?

Addyi is a treatment for the decrease in sexual desire in women who are not going through menopausal changes and have not experienced a lack of sexual desire before. This medication is used only when the lack of sexual desire isn't due to a medical issue or mental illness, a relationship, or the use of medications or drugs.

Addyi is not suitable for women who are already going through menopausal changes. The medicine is not recommended for use by men.

Warnings

It is not recommended to drink Addyi within two hours of drinking alcohol.

Discuss with your doctor your current medications and all the ones you begin or stop taking. Numerous drugs interact, and certain drugs shouldn't be taken together.

Before you Take this Drug

You shouldn't take Addyi in the event that you are allergic to flibanserin or you are suffering from:

  • Liver disease liver disease
  • If you've recently drunk alcohol.

It is not recommended to drink Addyi within two hours of drinking alcohol.

Certain medicines may cause undesirable or harmful effects when used together with Addyi. Your doctor could alter your treatment regimen in the event that you use any of the following:

  • Nefazodone;
  • As an antibiotic, ciprofloxacin, clarithromycin, erythromycin, and telithromycin
  • Antifungal medicine: fluconazole, itraconazole, ketoconazole, and posaconazole;
  • Antiviral medicine for treating hepatitis C: boceprevir, telaprevir, and oceprevir.
  • The heart and blood pressure medication conivaptan, dilitiazem, verapamil,
  • HIV or AIDS medicine: atazanavir, fosamprenavir, indinavir, nelfinavir, ritonavir, and saquinavir.

To ensure the safety of Addyi, inform your doctor if you are suffering from:

  • Alcoholism (or if you consume alcohol);
  • Drug dependence;
  • Depression and mental health
  • Low blood pressure.

It isn't known if this medication will cause harm to a baby who is not yet born. Consult your physician if you are pregnant or planning to become pregnant.

Do not breastfeed during the course of this medication.

Flibanserin is not permitted for use by anyone less than 18 years of age.

How to Take Addyi?

Use Addyi exactly as directed by your physician. Follow all instructions on the label of your prescription and also read the medication guide or instructions sheets.

Use Addyi only at night.

Do not drink alcohol for a minimum of two hours prior to taking Addyi or the following morning. Alcohol may cause you to suffer from high blood pressure, which is dangerous if combined with flibanserin.

Don't take a dose at bedtime. If you had a drink less than two hours prior to bedtime.

Flibanserin may lower blood pressure and cause you to become dizzy. If you feel dizzy following the use of this medicine, take a nap if you aren't in bed already.

It could take as long as 8 weeks before symptoms improve. Use the medication exactly as prescribed, and notify your physician if your symptoms don't improve.

Keep at room temperature, free of heat and moisture.

Details on Dosage:

Usual Adult Dose for Hypoactive Sexual Desire Disorder:

100 mg taken orally throughout the day, before sleep

The duration of the treatment The drug is recommended to be stopped after 8 weeks if the patient is not able to show an improvement in their symptoms.

Comments: This medication is not intended to improve sexual performance, and it is not a suitable treatment for postmenopausal women or men.

Treatment for premenopausal women suffering from acquired generalized hypoactive sexual desire disorder (HSDD), which is characterized by a lack of sexual desire and causes intense distress or difficulties in relationships and is not caused by an underlying medical or mental disorder, issues in relationships, or the effects of a drug or another substance,

What Happens If I Miss the Dose?

Do not miss the missed dose, and take the medication the next day at night. Don't consume Addyi at the beginning of your day, and don't have two doses at a time.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Consuming alcohol while taking this medication could cause unwanted or dangerous adverse consequences.

Grapefruit could interact with flibanserin and lead to undesirable negative side effects. Beware of using products made from grapefruit.

Do not take any of the following prescription or herbal supplements without consulting your physician:

  • Cimetidine;
  • Gingko biloba;
  • Resveratrol;
  • John's wort

Dizziness and low blood pressure may result in accidents or falls. Avoid operating machinery or driving for at least 6 hours following your use of Addyi and for a minimum of 6 hours until you know how this drug will affect you. Your reaction could be impaired.

Be careful not to get up too fast from a lying or sitting position. You could be dizzy.

Side Effects of Addyi

See a doctor immediately, If you are experiencing symptoms that indicate you are experiencing an allergic reaction, Addyi: hives, breathing problems, and swelling of your lips, face, and tongue.

Contact your doctor immediately. If you suffer from:

  • Severe drowsiness;
  • Feeling lightheaded, as if you're going to faint.

Common Addyi side effects can include:

  • Dizziness, drowsiness;
  • Tiredness;
  • Nausea;
  • Dry mouth
  • Trouble sleep.

This isn't a complete list of all the side effects. Others could happen. Consult your physician to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with Other Drugs

It is sometimes not recommended to take certain medicines together. Certain medications can alter the blood levels of other medications you are taking, which could cause more side effects or make the medication less effective.

Combining this medication with other medications that cause you to become drowsy could increase the severity of this effect. Talk to your doctor prior to using opioid medications, sleeping pills, muscle relaxers, or medication for anxiety or seizures.

A variety of drugs interact with flibanserin. This includes over-the-counter and prescription medications, vitamins, and herbal products. The interactions of all drugs are not included in this list. Discuss with your physician all the medications you are currently taking and any medications you begin or stop taking.

 

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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