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Magnesium Sulfate-Sodium Chloride (injection)

Generic Name: Magnesium sulfate (injection) [ mag-NEE-see-um-SUL-fate].
Name of the Brand: Magnesium Sulfate Sodium Chloride Injection.
Classes of Drugs: Laxatives, minerals and electrolytes, and miscellaneous anticonvulsants.

What is Magnesium sulfate-sodium chloride?

Magnesium is a naturally occurring mineral that is essential for numerous systems within the body, particularly the nerves and muscles. Magnesium sulfate and sodium chloride injections are employed to manage hypermagnesemia (low concentrations of magnesium found in the blood). Magnesium sulfate-sodium chloride injections are also used to stop seizures in pregnant women suffering from issues like pre-eclampsia, eclampsia, or toxemia during pregnancy. Magnesium sulfate and sodium chloride injections can be used for other purposes not covered in this guide.

Adverse effects of Magnesium Sulfate-Sodium Chloride

See a doctor immediately. Get medical attention immediately if you notice symptoms that are warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, and throat. Inform your caregiver immediately if you are suffering from:

  • Feeling like you might pass out.
  • Sweating, anxiety, and a cold feeling.
  • Flushing (warmth of redness, warmth, or tingling sensation).
  • Breath that is weak or shallow.
  • Extreme tiredness and feeling weak.
  • Numbness or tingling sensation in your lips; tightness of muscles or contraction; excessive reflexes.

This isn't a complete list of all the side effects. Other side effects could be present. Contact your doctor to seek medical advice on adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Sabril, Clonazepam, Lamotrigine, Diazepam, Topiramate, Lamictal, and Klonopin.


If you can, before receiving magnesium sulfate-sodium chloride, inform your physician about kidney problems, heart disease, stomach or intestinal conditions, or if you're dehydrated. Also, inform your doctor if you drink alcohol or coffee regularly, if you smoke, or if you are a user of any street drugs.

Before you take this drug

Talk to your doctor if you take regular amounts of caffeine or alcohol, if you smoke, or if you are using any drug that is sold on the streets. These factors can influence the way magnesium sulfate sodium chloride injection is absorbed by your body. If you can, before receiving magnesium sulfate-sodium chloride, inform your doctor whether you suffer from:

  • Kidney disease.
  • Heart disease.
  • A stomach or intestinal problem.
  • If you are dehydrated.

It is not recommended to use magnesium sulfate or sodium chloride when you are pregnant. It could harm the unborn baby. Make sure you use effective contraception and inform your physician if you become pregnant while you are taking treatment. Magnesium sulfate may be absorbed into the milk of a nursing baby and could harm a nursing child. Do not take this medication without consulting your physician, whether you are breastfeeding or not. In an emergency, it is not always feasible to inform your family members or caregivers that you are expecting or breastfeeding. It is important that the doctor caring for the baby or your pregnancy has been informed that you've taken this medication.

How to take magnesium sulfate-sodium chloride?

Magnesium sulfate and sodium chloride are administered to muscles or into a vein using an IV. The injection will be administered in a hospital or clinic environment. Your blood pressure, breathing level, oxygen levels, and other vital indicators are closely monitored while you receive magnesium sulfate and sodium chloride.

What happens if I miss a dose?

Because magnesium sulfate-sodium chloride is administered by a health expert, you aren't likely to not take the dose.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Follow the doctor's advice regarding any limitations on foods, drinks, or any activity.

Interaction with other drugs

Discuss with your doctor any medications you are taking as well as the medicines you begin or stop taking during the course of treatment, particularly the intravenous (injected) antibiotics. Other medications may be incompatible with magnesium sulfate, which includes prescription and over-the-counter medications, vitamins, and herbal products. Inform your health professionals about any medications you take currently and all medicines you stop or start using.