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AbobotulinumtoxinA

Generic Name: AbobotulinumtoxinA (Dysport) [A-boe-BOT-ue-LYE-num-TOX-in-A]
The Brand Name is Dysport.
Dosage Forms:There are two dosage types available: injectable powder for injection (500 units) and intramuscular powder for injection (300 units).
Drug class: Skeletal Muscle Relaxants 

What  is AbobotulinumtoxinA (Dysport)?

Dysport

is used by adult patients to manage neck dystonia (abnormal head position) and neck discomfort.

Dysport can also be used to treat muscle spasms and stiffness (spasticity) of the hands, arms, legs, and feet in children and adults who are at least two years old. Dysport is not a treatment for spasticity due to cerebral spasms.

Dysport can also be used to temporarily reduce facial wrinkles. skin wrinkles 

Side Effects of AbobotulinumtoxinA (Dysport)

Seek medical attention immediately. Get medical attention immediately if you notice warning signs of an allergic response, such as symptoms of hives, breathing difficulties, or feeling like you may faint or swell up on your lips, face, and tongue.

The botulinum toxins in Dysport can be spread across the body beyond the area where it was injected.

The result has been dangerous, life-threatening adverse reactions for some people who had botulinum injections even for cosmetic purposes.

Get in touch with your doctor right away in the event that you suffer from any of the following side effects (up to a few hours or weeks following the injection):

  • Difficulty breathing, speaking, or swallowing;

  • Vocal slur, drooping eyelids;

  • Issues with vision;

  • Abnormal or extreme muscle weakness (especially in an area of the body that was not infused by the drug);

  • Discomfort or burning sensation after you pee; pain or burning when you urinate; pink or red urine;

  • Loss of bladder control or

  • Vision changes include eye pain, severe dryness, or eye irritation (your eyes could be more sensitive to light).

Adverse effects

  • Muscles, and problems with balance

  • Headaches, muscle or joint pain, and pain in your arms and legs;

  • Eyesight changes; drooping or sagging eyelids; eyes that are dry or puffy;

  • A reaction in which the medication was injectable (pain, itching, and redness, as well as warmth, numbness, bruising,swelling, and tingling);

  • Nausea;

  • The fever, cough, sore throat, and stuffy nose;

  • Changes in voice, dry

    mouth, and trouble swallowing

  • Feeling exhausted.

This isn't a complete list of all the side effects. Other things could happen. Contact your doctor for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Warnings

The botulinum toxin in Dysport can be spread to other body parts beyond the area where it was injected. It can lead to adverse effects that could be life-threatening.Consult your physician immediately in the event of an unsteady voice, low eyelids, vision problems, muscle weakness, severe loss of bladder control, or difficulty breathing, talking, or swallowing.

Before using this medication before taking this medication, consult your doctor.

It is best not to receive this medication if you're allergic to botulinum toxin, cow's milk, or have an

infection

on the site where the medicine is injected. Do not inform your doctor if you have had any adverse reactions following botulinum injections in the past.

Inform your doctor if you were ever diagnosed with:

  • Amyotrophic lateral degeneration (ALS, also known as "Lou Gehrig's disease");

  • Myasthenia gravis;

  • Lambert-Eaton syndrome;

  • A breathing disorder like asthma as well as an emphysema-related condition;

  • difficulties swallowing;

  • Facial muscle weakness in the facial muscles (droopy eyelids and a weak forehead, or trouble with your eyelids);

  • A change in the normal look of the face.

  • A seizure disorder;

  • Bleeding issues;

  • A heart rhythm disorder

  • Diabetes;

  • Dry eyes after having received botulinum toxin previously;

  • A recent or planned operation (especially in your face) or

  • Botulinum toxin injections that are not as common, including Botox, Myobloc, or Theomic, 

Dysport is derived from human plasma donated by donors and could be contaminated with viruses or other infectious agents. Plasma donated to the clinic is examined and treated to decrease the chance of contamination; however, there is the possibility that it may be a carrier of diseases. Consult your physician about the possibility of risks.Consult your physician if you are breastfeeding or pregnant.

How to Take Dysport?

Dysport injections are only administered by a certified medical expert, regardless of whether they are intended for cosmetic reasons.This medication is injected into the muscles by a medical professional. Dysport injections should be given between 3 and 6 months. Children shouldn't receive treatment with Dysport more often than every 12 to 16 weeks.

Dysport injections can be administered to multiple areas at the same time, depending on the issue being treated.The effects of a Dysport injection are only temporary. The symptoms could return within three months. Following repeated injections, it could take less time before symptoms recur, particularly if your body develops antibodies to the botulinum toxins.

Don't seek botulinum injections with more than one physician at the same time. If you switch providers, you should inform your new doctor of the length of time since your last botulinum injection.Making use of this medicine more frequently than recommended will not increase its effectiveness and may cause severe adverse reactions.

What Happens If I Miss a Dose?

Because botulinum toxin has only a short-term effect and is administered at intervals that are widely spaced, a missed dose is unlikely to cause harm. 

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

The symptoms of an overdose might not manifest immediately but may include muscle weakness, difficulty swallowing, or a weak or shallow breath.

What Should be Avoided?

Dysport can affect the depth of vision and/or perception. Avoid driving or engaging in hazardous activities until you are aware of what the effects of this medication will be on your vision and depth perception.Be careful not to return to normal routines too quickly following an injection.

Interaction with Other Drugs?

Other medications can cause an increase in certain side effects of Dysport and other drugs, such as cold and allergy medications, muscle relaxers, sleeping medications, bronchodilators, urinary or bladder medications, and irritable bowel medications. Consult your physician if you frequently use any of these medications.Inform your doctor about all other medicines you take, particularly:

  • An injected antibiotic—amikacin, gentamicin, kanamycin, neomycin, paromomycin, streptomycin, or tobramycin.

This list isn't complete. Other drugs can interact with Dysport, such as medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions between drugs, which are included in this article. Don't start an entirely new medication without informing your doctor that you've previously taken Dysport.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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