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Generic Name: Neomycin “nee-oh-my-sin” [neo-oh-my-sin]
The Brand Names are Mycifradin and Neo-Fradin. Neo-Tab, Mycifradin
Dosage Format: Oral tablet (500 mg)
Drug Class: Aminoglycosides

What is Neomycin?

Neomycin is an antibiotic that can be used to treat bacteria that cause infections inside the digestive tract. Neomycin can also be used to alleviate those symptoms that are associated with hepatic coma.

Sometimes, neomycin is given along with another antibiotic.Neomycin is also employed for other purposes that are not covered in this guideline for medication.

Side effects of Neomycin

See a doctor immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and throat.

Neomycin could cause severe adverse consequences. Consult your physician immediately. If you suffer from:

  • The sensation of tingling or numbness is felt under your skin.
  • Hearing problems (even long after you stop taking neomycin);
  • Muscle twitching, seizure;
  • Breath that is shallow or weak; slow or shallow breathing
  • Kidney problems: swelling, less urination, fatigue, or feeling exhausted.

Common negative side effects of neomycin could include:

  • Nausea, vomiting,

There isn't an exhaustive description of the various negative consequences. The possibility of other adverse side effects is there. Consult your physician for medical advice regarding adverse reactions. It is possible to report any adverse reaction to FDA by calling 1-800-FDA-1088.


Neomycin could damage your kidneys or cause hearing loss. Hearing loss could be permanent if you use too much Neomycin or use it longer than recommended.

Before you take this drug

Neomycin should not be taken when you are allergic to the drug or are suffering from:

  • Ulcerative colitis, Crohn's disease, or another digestive disorder;
  • A blockage within your intestines.
  • An allergy to similar antibiotics, such as amikacin, gentamicin, streptomycin, paromomycin, or tobramycin.

Inform your doctor if you have ever suffered from:

  • Kidney disease;
  • Myasthenia gravis;
  • Parkinson's disease.

The baby could be harmed if it isn't yet birthed. Inform your doctor if you are expecting.Do not breastfeed.Neomycin should not be given to a child unless you have medical guidance.

How to take Neomycin?

Follow the directions on the prescription label and review all medication guides and instruction sheets. Make sure you use the medication precisely as directed.Do not take more than prescribed or for longer than two days. High doses or prolonged use of Neomycin may result in permanent hearing loss.

Use this medicine even if your symptoms do not improve. Dosing too much can make your disease immune to the medication. Neomycin does not treat an infectious disease (the flu or a common cold).Drink plenty of fluids throughout the day to stay well hydrated.Hearing and kidney functions might require a test.

Neomycin for hepatic coma is typically taken for 5–6 days. Avoid eating foods high in protein throughout this period. Follow all instructions from your dietitian or doctor regarding adding protein back into your diet following treatment.

Inform your doctor if you are planning a procedure.

Keep tightly sealed in a cool, dry place away from heat and humidity.

What happens if I miss the dose?

You should take the medication as quickly as you are able, but do not take any missed doses if you are close to the time of the next dose. Don't take two doses at a time.

What happens If I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Don't share Neomycin with other people, even if they suffer from similar symptoms to yours.

Interaction with other drugs

Neomycin may cause kidney damage, particularly when you are also taking specific medications for cancer, infections, osteoporosis, organ transplant rejection, digestive issues, high blood pressure, or arthritis pain (including Advil, Motrin, and Aleve).

Inform your doctor about any other medications you take, particularly:

  • Other antibiotics,
  • Digoxin;
  • Fluorouracil;
  • Methotrexate;
  • Vitamin B-12;
  • A blood thinner (Warfarin, Coumadin, Jantoven);
  • Diuretic, also known as a "water pill—furosemide or ethacrynic acid.

This list isn't complete. Other medications can affect Neomycin, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions between drugs that are listed here.



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