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Gammagard S/D IGIV

Generic name: immune globulin (IGIV) (intravenous) [im-MYOON-GLOB-yoo-lin]
Brand names: Bivigam, Flebogamma, Gammagard S/D, Gammaplex, Octagam,… show all 8 brands
Drug class: immune globulins

What is Gammagard S/D IGIV?

Intravenous immunoglobulin is used for the treatment of primary immune deficiency. IGIV can also be used to increase the number of platelets (blood clotting cells) in patients with immune thrombocytopenic purpura. IGIV can also be used to prevent certain infections among people with B-cell chronic lymphocytic leukemia. IGIV can also be used to treat Kawasaki syndrome, preventing aneurysms caused by a weakening main artery of the heart. IGIV can be used in other ways not mentioned in this guide.

Side effects of Gammagard S/D IGIV

If you notice any of these symptoms of an allergic reaction, seek medical assistance immediately: difficulty breathing, hives or swelling on lips, face, tongue or throat. During the injection, some side effects can occur. You should tell your caregiver if your symptoms include feeling dizzy, nauseated, or light-headed.

Gammagard S/D may cause serious side effects. If you experience:

  • A blood cell disorder: pale, yellowed, or dark urine; fever or confusion;
  • Dehydration symptoms include feeling thirsty, hot, or unable to urinate. Heavy sweating or dry and hot skin.
  • Kidney problems: swelling, weight gain, shortness of breath, little or no urine,
  • Blue lips, toes, or fingers are signs of lung problems.
  • Signs of an infection: severe headache, stiff neck, eye pain, and increased sensitivity;
  • Signs of a blood clot include shortness of breath, chest pain when deep breathing is done, rapid heartbeat, numbness on one side, swelling, warmth, or discoloration of an arm or limb.

Some of the side effects that Gammagard S/D can cause include:

  • Headache, joint, or muscle pain.
  • Fever, chills, or sweating
  • Stomach pain, nausea, and diarrhea;
  • Increased blood pressure and rapid heartbeats
  • Dizziness, fatigue, and a lack of energy are all symptoms that can be experienced.
  • Stuffy nose, sinus pain;
  • Pain, swelling, irritation, or burning around the IV needle

There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA with regard to side effects is possible by dialling 1-800-FDA-1088.


Gammagard Blood clots can be caused by S.D. The risk is higher in older adults, people with heart disease, blood circulation issues, and those who have experienced blood clots. Blood clots can also occur during prolonged bed rest, when using birth-control pills, hormone replacement therapy, or while wearing an IV catheter. If you experience chest pain, difficulty breathing, rapid heartbeats or numbness, weakness, or swelling in your arm or leg, as well as warmth and discoloration, call your doctor immediately. This medication can also damage your kidneys. especially when you have kidney disease and/or are taking certain medications. If you notice any symptoms of kidney disease, such as swelling, rapid growth, or little or no urine, tell your doctor immediately.

Before you take this drug

This medicine may not be suitable for you if:

  • You have experienced an allergic reaction to immune globulins or blood products.
  • You have a deficiency of immune globulin A with antibodies to IgA.
  • You are allergic to corn.

IGIV may cause kidney or blood clot problems, particularly in older adults and people with certain medical conditions. Tell your doctor about:

  • Heart problems, poor circulation issues or "thick blood";
  • A stroke or clot of blood;
  • Kidney disease
  • Diabetes;
  • Sepsis is an infection.
  • If you use hormones (birth control pills or hormone replacement therapy),
  • If you've been on bedrest for a long time,
  • If you already have an intravenous central catheter (IV),

If you have been exposed to measles or traveled to an area with a high prevalence of this disease, you may need to adjust your dose. Notify your doctor immediately if you become pregnant or nursing. The immune globulin made from human plasma can contain viruses and other infectious agents. Plasma is treated and tested to reduce the chance of contamination. However, there is still some risk. You should ask your doctor if there are any risks.

How to take Gammagard S/D IGIV?

IGIV is administered as an intravenous infusion, typically once every three to four weeks. This injection will be given by a healthcare provider. Gammagard S/D can help to improve blood flow, which will keep your kidneys functioning properly. Blood or urine tests may be required frequently. It can also affect certain medical tests. Inform any doctor that treats you about your use of IGIV.

What happens if I miss the dose?

If you cannot attend your appointment, contact your physician and request instructions on what steps need to be taken in your situation.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Consult your doctor prior to receiving a “live” vaccine when using IGIV. It may not protect you as well or work as effectively. Live vaccines are available for measles (MMR), rubella, mumps (R), rotavirus (rotavirus), typhoid (typhoid), yellow fever (yellow fever), varicella (chickenpox), and zoster (shingles).

Interaction with other drug

IGIV may harm your kidneys if you are also taking certain medications for cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, pain, or arthritis. Other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal supplements, may also affect IGIV. Inform your doctor of all the medicines you are currently taking and those that you have started or stopped using.