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Brand name:Lexiscan
Dosage form:Intravenous Solution (0.4 mg/5 mL)
Class of drugs: agents that cause cardiac stress

What is Regadenoson?

The regadenoson preparation is to be given before a radiologic examination (x-rays) of the blood flow in the heart, which will test for coronary artery disease.Regadenoson can be used in other ways not mentioned in the medication guide.

Side effects of Regadenoson

If you experience any of the following symptoms of an allergy: difficulty breathing, hives, swelling in your lips, face, throat, or tongue

If you:

  • Dizziness or vertigo, rapid heartbeats and warmth, or even a tingling sensation;
  • Chest tightness, difficulty breathing,
  • Weak or shallow breathing
  • Pain in your chest or pressure that spreads to the jaw or shoulder
  • A seizure;
  • Low blood pressure gives you a feeling of being light-headed, as if you could pass out.
  • High blood pressure—a severe headache
  • Signs of stroke include sudden numbness and weakness, especially on one side, severe headaches, slurred words, or balance issues.

Regadenoson can cause the following side effects:

  • Trouble breathing
  • Headache, dizziness;
  • Chest pain or discomfort
  • Nausea;
  • Flushing (warmth or redness)

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report any side effects.

Similar/related drugs

Adenocard, Lexiscan, Adenosine, Mannitol, Glucagon, Dipyridamole, and Arginine


If you suffer from a serious condition of the heart, such as an AV block (or "sick-sinus syndrome") or a pacemaker, you should avoid regadenoson.

Before you take this drug

Regadenoson should not be used if the patient is allergic or has a severe heart problem, such as

  • 2nd or third-degree AV block
  • The "sick sinus" syndrome (unless you are wearing a pacemaker)

You may be at greater risk for breathing difficulties, stroke, or cardiorespiratory arrest if you receive regadenoson. Speak to your doctor regarding your risk.

If you've recently had nausea and diarrhea, Or if:

  • Asthma, or COPD.
  • Chest pain or heart disease
  • Blood circulation problems
  • Coronary artery disease is a condition where the arteries become clogged.
  • Seizures;
  • Heart Disease High blood pressure
  • If you are also taking dipyridamole or theophylline,

Regadenoson is known to cause harm to an unborn child. Inform your doctor that you're pregnant.Don't breastfeed for 10 hours following regadenoson. Throw away any collected milk if you are using a pump. Don't feed your baby.

How to take Regadenoson?

Regadenoson can be infused into the vein. This injection will be given by a healthcare professional.Other intravenous medications may be administered to allow the blood vessels on the radiologic exam to be more easily seen.During your stress test, you will closely monitor the oxygen level, breathing rate, blood pressure, and other vital indicators.

Details on dosage

Adult dose for radionuclide myocardial perfusion study:

Use a catheter or a needle of 22 gauge or greater to inject 0.4 mg of rapid intravenous (in approximately 10 seconds) in a vein peripheral.
Comment: Administer 5 ml of saline immediately after the injection. After the 5 mL saline rinse, administer the radionuclide imaging agent for myocardial blood flow 10–20 seconds later. Radionuclide can be directly injected into the catheter with this drug.
Use radionuclide myocardial blood flow imaging for patients who are unable to exercise.

What happens if I miss the dose?

You are unlikely to have a regadenoson dosing regimen since it is administered by a medical professional as part of preparation for a medical test.

What happens if I overdose?

Overdoses are unlikely because this medication is administered by healthcare professionals in a medical environment.

What should be avoided?

Do not consume caffeine-containing beverages or coffee for 12 hours prior to your stress test.

Interaction with other drug

Regadenoson should only be taken 12 hours after taking other medicines.Tell your doctor about all medications you are taking, including:

  • Aminophylline;
  • Dipyridamole

Regadenoson can be affected by other drugs, such as prescription medicines, over-the-counter medications, vitamins, and herbal products. Inform your doctor of all the medicines you are taking and those that you stop or start using.