What is Zytiga?
Zytiga reduces androgen production within the body. The hormones known as androgens can be male hormones that may cause prostate cancer growth. Gland.
Zytiga is used along with steroid medications (prednisone or methylprednisolone) to treat prostate cancer, which can spread to various areas of the body.Zytiga is a treatment for men with prostate cancer that can't be treated surgically or with other medications.
Warnings
You shouldn't take Zytiga in the case of an extremely severe liver disease.Before taking this medicine, inform your doctor whether your blood levels are low for potassium, or if you have any kind of disease or high blood pressure, congestive heart failure, an underlying heart condition or fluid retention, recently had a heart attack, or issues with your pituitary or adrenal gland.
While Zytiga is not recommended for the use of women, the medication can cause harm to an unborn baby and cause birth defects. Tablets are not recommended for use by women who are pregnant or may become pregnant.
While you're using Zytiga and for a minimum of one week following the end of your treatment, use a condom to stop the transfer of the medication to your partner in case they are pregnant. Make use of a condom along with another method of birth control if you suspect that your sexual partner might become pregnant.
Before you take this drug
It is not recommended to use Zytiga if you have an allergy to Abiraterone.Zytiga is not intended for use by children or women.
To ensure that this medication is suitable for you, inform your physician if you've had any of the following:
- Liver disease;
- Diabetes (especially when you take pioglitazone or repaglinide);
- Heart issues, high blood pressure;
- A heart attack;
- Low levels of potassium are present in the blood.
- Troubles related to your adrenal gland or the pituitary gland.
Abiraterone may harm an unborn baby if the mother has contact with it while pregnant. A Zytiga tablet is not recommended for pregnant women or those who are likely to be pregnant. The medicine from the tablet that has been broken could be absorbed by the skin.
Abiraterone may also harm a baby born in the event that the father takes this medicine prior to the moment of conception or the pregnancy.Utilize effective birth control if your partner in sex is pregnant or may be pregnant. Use birth control for a minimum of 3 weeks after the last dose.
Similar/related drugs
Estradiol, Premarin, Xtandi, Casodex, and Lynparza
How to take Zytiga?
Zytiga is generally taken once daily, and you may also take a steroid at least twice a day. Follow the doctor's instructions for dosage extremely carefully.Follow all the instructions on the prescription label, and make sure you read all medication guides or instructions sheets.The dosage of abiraterone you require could change when you switch to a new brand, strength, or type of medication. Be sure to use only the medication your doctor has prescribed.
Your dose of steroid could be altered if you are suffering from an infection or are under tension. Don't alter your dosage or stop taking the steroid medication without consulting the advice of your physician.Drink this medicine by drinking a glass of water.You can take Yonsa without or with food.
You should take Zytiga with a full stomach. Do not eat or drink anything for at least two hours before or one hour after taking the dose.Take the tablet in one swallow and make sure you don't crush, chew, or break it.
Your blood pressure is likely to be monitored regularly, and you might require periodic blood tests. If you are diabetic, your blood sugar levels should be examined with care, especially when you are taking pioglitazone or repaglinide.
You shouldn't stop taking Zytiga or your steroid medication abruptly. Follow the directions of your physician on tapering the dose of prednisone.Place it in a cool, dry place far from heat and moisture.
Details on dosage
Usual Adult Dose for Prostate Cancer:
Metastatic CRPC:
The recommended dosage is 1000 mg once a day orally (in combination with methylprednisolone 5 mg daily orally).
A modified formulation of 500 mg taken orally every day (in combination with methylprednisolone, 4 mg orally twice daily)
The metastatic risk is high. CSPC:
Regular dosage: 1000 mg taken orally every day (in combination with methylprednisolone: 5 mg orally every day).
A micronized formulation of 500 mg taken orally each day (in conjunction with methylprednisolone for 4 mg orally twice daily)
Comments:
Note: Different brands of abiraterone offer different indications and dosage guidelines. Here are the recommended dosing guidelines. Check the manufacturer's information for the product prior to prescribing this medication.
Uses:
Together with prednisone, it is treating patients suffering from:
Metastatic castration-resistant prostate cancer (CRPC)
Prostate cancer with a high risk of metastatic castration (CSPC)
Do I be concerned if I miss a dose?
Don't miss the missed dose, and then take the medication the next day. Don't do two doses at the same time.
Contact your doctor for advice. If you missed multiple doses of Zytiga,
What will happen if I take excessively?
Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.
What should be avoided?
Don't eat anything for at least two hours prior to taking Zytiga or at least one hour following your dose. Foods can increase the amount of abiraterone that your body absorbs and could cause adverse side effects.
Do not take a herbal supplement that contains St. John's wort.
Side effects of Zytiga
See a doctor immediately. If you are experiencing symptoms that indicate an allergy reaction, Zytiga: hives, breathing problems, and swelling of your lips, face, or tongue
See your doctor right away. If you suffer from:
- The swelling of your ankles, feet, or legs; discomfort in your legs;
- Irregular or rapid heartbeats;
- Feeling lightheaded, like you're about to go into a coma.
- Extreme headache severe headache, blurred vision the pounding of your neck or in your ears;
- Pain or burning sensations when you urinate
- Red blood cells are low (anemia)—pale skin, fatigue, and feeling lightheaded or short of breath; cold feet and hands;
- Low blood potassium: leg cramps, constipation, irregular heartbeats, fluttering of your chest, thirst, or urination You may also experience numbness, tenderness in muscles, or a feeling of limpness.
- Stomach symptoms, stomach pain (upper right side), nausea, vomiting, dark urine, jaundice (yellowing of the eyes or skin), or
- Extreme lower blood sugar—headache, hunger, sweating, irritability, anxiety, fast heart rate, and a feeling of anxiety or shaking.
Common Zytiga side effects may include:
- Feeling very tired or weak
- Feeling very hot;
- High blood sugar levels;
- Elevated blood pressure
- Swelling in your feet or legs;
- Anemia or low blood potassium levels;
- Painful urination;
- Unusual liver function test results or different blood tests
- Joint inflammation or pain;
- Headache;
- Nausea, vomiting, diarrhea;
- Symptoms of the cold, like nasal stuffiness, sneezing, coughing, and a sore throat.
It isn't a complete list of the possible consequences, but other effects may occur. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.
Interaction with other drugs
There are times when it's not recommended to take certain medications in combination. Certain drugs may affect the blood levels of other medications you are taking, which could create side effects or render the medication less effective.
Discuss with your doctor all the medications you take. Numerous drugs can interfere with abiraterone, including:
- Other prostate cancer medications other prostate cancer medicines, including radiation Ra 223 (which may increase the chance of breaking bones while you're taking Zytiga), as well as
- Pioglitazone and repaglinide for treating the condition of diabetes may cause severe blood sugar hypoglycemia while taking Zytiga.
This list isn't complete, and a variety of other medications could interfere with Abiraterone. This includes prescription and over-the-counter medicine, vitamins, and herbal products. There are many possible interactions between drugs. Are included here.
