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Generic name: loteprednol and tobramycin ophthalmic [LOVE-the-PRED-nol-and-TOE-bra-MYE-sin-off-THE-mick]
The class of drug: Ophthalmic steroids with anti-infectives

What are Zylet Eye Drops?

Zylet eye drops include the combination of loteprednol with tobramycin. Loteprednol is a steroid. It blocks the release of substances within the body that trigger inflammation. Tobramycin is an antibiotic that fights bacteria.

Zylet eye drops are utilized to treat inflammation of the eye caused by infection, surgery, allergies, and other ailments.Zylet could also be used to treat conditions not covered in this medication guide.


It is not recommended to take Zylet if you are suffering from any fungal, viral, bacterial, or fungal eye infection (including chickenpox or herpes).Do not apply the dropper to any surface, such as the eyes or your hands. The dropper is clean. If it is infected, it can cause an infection in the eye.

Contact lenses are required if you use them. You must remove them prior to applying Zylet. Consult your physician to determine if your contact lenses are able to be put back in after applying Zylet. Zylet might have a preservative (benzalkonium chloride), which can create discoloration in contact lenses.

Before you take this drug

It is not recommended to take Zylet when you are sensitive to tobramycin, loteprednol, or any other steroids. Do not take Zylet if you suffer from any kind of fungal or bacterial infection that is present in your eye (including chickenpox or herpes).

To ensure that Zylet is not harmful to you, consult your physician. If you are suffering from:

  • Glaucoma;
  • Cataracts (or cataracts if you've had surgery for cataracts) or
  • Eye herpes infection

It isn't known if Zylet could harm an unborn baby. Consult your physician if you are expecting or planning to become pregnant while taking Zylet.

It isn't clear if loteprednol and tobramycin enter breast milk or whether they can harm the nursing infant. Tell your physician if you have a baby in your.Avoid giving Zylet to children less than 6 years old without medical guidance.

How to take Zylet?

Make use of Zylet eye drops precisely as prescribed by your physician. Follow the directions on the prescription label. A doctor could change the dose in order to ensure that you get the most effective effects. Don't take this medication in greater or lesser quantities or for longer than prescribed.

Do not take this medication when wearing contact lenses. This medicine may contain a preservative that could cause the discoloration of soft contact lenses. Take a minimum of 15 minutes after taking this medication before inserting contacts.

Shake the drops for the eyes properly prior to every use.

Cleanse your hands prior to using these eye drops.

To apply drops to the eyes:

  • Turn your head slightly back and then pull your lower eyelids to create an eyelid pocket. Place the dropper over the eye, with the tip downwards. Keep your eyes upwards and away from the dropper, and squeeze out one drop.
  • You can close your eyes for two or three minutes with your head tilted down without blinking or squinting. Press your finger gently to the inner corner of the eye for around one minute, to stop the fluid from leaking into the tear duct.
  • Make sure you only use the number of drops that your doctor has advised. If you are using multiple drops, you should wait at least five minutes in between each drop.
  • At least 10 minutes prior to using or using any eye drop that your physician has recommended.

Do not touch the edge of your eyedropper, or put them directly in your eyes. Drops contaminated with bacteria could cause eye infections and lead to serious vision problems.Don't use drops for your eyes if they have changed color or contain particles. Consult your pharmacist about new medications.

Make sure to take this medicine for the prescribed duration. Your symptoms could worsen until the infection is fully removed. The absence of doses can increase the risk of a subsequent infection that is resistant to antibiotics.

Contact your doctor if symptoms do not improve or if your symptoms become worse after using Zylet.If you are using Zylet long-term, you could require regular medical exams at the doctor's office.Keep it at room temperature, far from heat and moisture. Don't freeze. Close the bottle when not being used.

Do I be concerned if I miss a dose?

Take the missed dose when you remember. Do not miss a dose If you're near the date of your next dosage. Don't use any extra medication to make up for the missed dose.

What will happen if I take excessively?

A high dose of Zylet isn't expected to be a danger. See a doctor immediately or call the poison assistance phone number 1-800-222-1222 if are a victim of a poisoning and have swallowed it accidentally.

What should be avoided?

Do not take other eye medications unless your doctor directs you to.

This medication can cause blurred vision and could cause a decrease in your ability to react. Be cautious if you drive or do any other activity that requires you to be able to clearly see.

Side effects of Zylet

See a doctor immediately. If you experience any of the following symptoms that indicate an allergy reaction: difficulty breathing; hives or swelling of your lips, face, or tongue.

Stop taking this medicine and contact your doctor immediately if you suffer from:

  • Eye swelling, redness, extreme discomfort, and drainage (which may be signs of infections)
  • Eye pain, blurred vision, or seeing halos in light sources
  • An appearance of cloudiness or haziness around your eyes or in your vision.
  • Intense burning or stinging in the eyes when you use eye drops.

The most common side-effects of Zylet can be:

  • Minor stinging or burning in the use of eye drops;
  • Greater sensitivity to light
  • Eyes with watery eyes
  • Puffy eyes

This isn't a complete list of possible side effects, and others could happen. Contact your doctor to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

It is unlikely that other medications that you inject or take orally will affect loteprednol or tobramycin, which are commonly used in the eyes. But there are many drugs that interact with each other. Inform your healthcare professionals about all medications you are taking, which includes medications that are prescribed and available over the counter, such as vitamins and herbs.