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Genric Name: Diclofenac diclofenac dye-KLOE’-fen-ak diclofenac [dye-KLOE-fen-ak]
The Class of Drugs: Nonsteroidal anti-inflammatory drugs

What is Zipsor?

Zipsor is an anti-inflammatory medication that is nonsteroidal (NSAID). Diclofenac potassium is a drug that works by cutting down the substances within your body that trigger inflammation and pain.Zipsor capsules can be used to treat moderate to severe pain in adults as well as paediatric patients who are 12 years old or older.Zipsor comes in a 25-mg liquid capsule.


Zipsor can cause bleeding in the stomach or intestines that can be fatal. This can happen at any time, even if you're taking Diclofenac.

The risk of suffering from an ulcer or intestinal bleeding rises with the following factors: taking medications referred to as "corticosteroids" and "anticoagulants" in combination with a longer duration of use, smoking, and drinking; advancing age; and being in poor health.

Zipsor could increase the chances of having fatal coronary heart attacks as well as strokes. Avoid using this medication prior to or following the procedure to bypass your heart (coronary bypass grafts for artery bypass, also known as CABG). Diclofenac may cause diarrhoea or stomach bleeding, which can be fatal.

Before you take this drug

Do not take Zipsor. If you're sensitive to diclofenac or if you've ever suffered an asthma attack or an extreme allergic reaction after using aspirin or an NSAID.Do not use Zipsor if you have an allergy to beef or the protein in beef.

To ensure this medicine is appropriate for you, consult your doctor if:

  • Heart disease and hypertension;
  • The stomach or within your stomach;
  • Asthma;
  • Kidney or liver disease,
  • If you smoke.

Diclofenac may affect ovulation, and it could make it more difficult to become pregnant when you're taking this medication.

If you're pregnant, then you shouldn't take Zipsor unless your physician tells you not to. Taking an NSAID in the last twenty weeks of your pregnancy could result in serious kidney or heart problems for the unborn baby and possibly complications related to the pregnancy.

It might not be safe to breastfeed while taking this medication. Consult your physician about any potential risks.Zipsor is not recommended to be used by anyone younger than 12 years old.

Similar/related drugs

Aspirin, Acetaminophen, Tramadol, Ibuprofen, Duloxetine, Paracetamol, and Naproxen

How to take Zipsor?

You should take Zipsor exactly as directed by your physician. Follow the directions on the prescription label, and be sure to read the medication instructions. The doctor may modify your dose. Make sure you take the dosage that is effective in treating your illness.

If you're using Zipsor for a long time, you could require regular medical exams.Keep the bottle at room temperature, far from heat and moisture. Close the bottle when not being used.

Details on dosage

Usual Adult Dose for Pain:

Diclofenac calcium liquid capsules, 25 mg, taken orally, 4 times per day
Diclofenac calcium liquid capsules cannot be interchangeable in conjunction with other diclofenac products that contain potassium salt or sodium.

Usual Paediatric Dose for Pain:

Diclofenac potassium liquid-filled capsules
12 years or older 25 mg oralally, at least four times per day.
Comments: Use the smallest effective dose that is the most efficient for the shortest time frame that is compatible with the treatment objectives.

What happens if I miss a dose?

Do the dose you missed as quickly as you can remember. Do not miss any doses if they are close to the date of your next dosage. Don't take any additional medication to compensate for the dose you missed.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

Avoid this

Beware of drinking alcohol. It can increase the chance of bleeding from your stomach.Avoid taking aspirin and different non-steroidal antidotes except if your physician advises you to.

Consult a physician or pharmacist before taking other medications for swelling, fever, pain, or other symptoms of the cold or flu. They could contain ingredients that are similar to diclofenac (such as aspirin, ibuprofen, ketoprofen, and naproxen).

Side effects of Zipsor

See a doctor immediately when you notice symptoms that you are experiencing an allergic reaction (hives, breathing difficulties, or swelling in your throat or face) or a severe reaction to your skin (fever, sore throat, burnt eyes, irritation, or an ailment that is purple or red and blisters and peels).

Get rid of Zipsor or seek medical assistance when you experience a severe reaction to medication that could affect the body in a variety of ways. Symptoms may include the appearance of a skin rash and fever, swelling of glands, muscle pains, abnormal bruising, severe weakness, or yellowing of the eyes or skin.

Seek medical attention immediately. If you are experiencing symptoms of an attack on your heart or stroke, chest pain spreading into your shoulder or jaw, suddenly feeling numb or weak in one area of your body, speech slurred, feeling breathless

Do not use Zipsor and consult your physician immediately if you suffer from:

  • The very first indication of any skin rash, regardless of its severity;
  • Flu-like symptoms;
  • Heart-related problems: swelling, rapidly gaining weight Feeling short of breath and swelling;
  • Kidney issues There is no or little urine; it is difficult or painful to urinate; there is swelling of your legs or arms; and you feel fatigued or short of breath.
  • Liver issues liver problems nausea, diarrhoea, and stomach discomfort (upper right side) Itching, fatigue, and dark urine are symptoms of jaundice (yellowing of the eyes or skin).
  • Symptoms of stomach bleeding: bloody or tarry stools; vomiting of blood; or vomiting that looks similar to coffee ground.

Common Zipsor side effects can include:

  • Indigestion, gas, nausea, vomiting, and stomach pain;
  • Diarrhea, constipation;
  • Headache, dizziness, or drowsiness;
  • Abnormal lab tests;
  • Itching, sweating;
  • Stuffy nose;
  • Elevated blood pressure;
  • The pain or swelling of your legs or arms.

This isn't a complete list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Consult your physician prior to taking Zipsor if you are taking any antidepressants. Taking certain antidepressants combined with an NSAID can cause bleeding or bruises easily.

Inform your doctor about all other medications, including:

  • Blood pressure or heart medication, which includes diuretics, also known as "water pills";
  • Other forms of diclofenac (Arthrotec, Flector, Pennsaid, Solaraze, Voltaren Gel)
  • Is a blood thinner (Warfarin, Coumadin, Jantoven);
  • Other nsaids include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), indomethacin (Meloxicam), and many more.

This list is not comprehensive. Other medications can interfere with diclofenac. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Some interactions with diclofenac are not listed here. Are included here.



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