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What is Vilobelimab?
COVID-19, a severe disease caused by the coronavirus SARS-cov-2 (Severe Respiratory Syndrome Coronavirus 2), is a serious illness. COVID-19 can be spread by air.
COVID-19 may affect your lungs and other organs. The symptoms can be mild or severe and include fevers, chills, coughs, sore throats, fatigue, headaches, body aches or headaches, loss of smell or taste, nausea, vomiting, or diarrhoea.
The US Food and Drug Administration has approved the emergency use of vilobelimab for COVID-19 among hospitalized adults within 48 hours after invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO), a heart-lung device that increases oxygen in the blood. The FDA has not approved vilobelimab to treat COVID-19.This medication guide does not list all possible uses of Vilobelimab.
Side effects of Vilobelimab
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue or throat.
Vilobelimab can cause serious side effects. If you experience:
- Signs of infection: fever, chills, and a sore throat. Body aches. Loss of appetite.
Some of the common side effects associated with vilobelimab include:
- Confusion;
- Constipation;
- Rash;
- Heartbeats irregular;
- Pain, swelling, or warmth in the leg;
- Pain and burning when urinating;
- Chest pain, breathing problems, and shortness of breath are all symptoms that may be present.
- A severe headache can cause blurred vision or a pounding sensation in the neck, ears, or head.
- Easy bruising, unusual bleeding, or purple or red patches under the skin
- Cold symptoms like stuffy noses, sneezing, and sore throats;
- Severe sleepiness; rapid heartbeats and breathing; feeling very sick
- Herpes symptoms include blisters and skin sores around the mouth and itching or tingling in your lower back or thigh.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Similar/related drugs
Paxlovid, molnupiravir, Actemra, Lagevrio, Remdesivir, Nirmatrelvir, and Ritonavir
Warnings
The US Food and Drug Administration has approved the emergency use of vilobelimab for COVID-19 among hospitalised adults if started within 48 hours of invasive mechanical ventilatory or extracorporeal membrane oxygenation (ECMO), a heart and lung machine that increases oxygen in the blood. The FDA has not approved vilobelimab to treat COVID-19.
Before you take this drug
Tell your doctor if:
- Allergies;
- An infection other than COVID-19
- Any serious illness
Inform your doctor if you are pregnant or planning to become pregnant.
How to take Vilobelimab?
Read all the instructions and directions included on the prescription label.A healthcare provider injects Vilobelimab into a vein in a hospital.
Details on dosage
Adult dose for COVID-19:
Only for investigational purposes
As follows:
Treatment should begin within 48 hours after intubation on Day 1, followed by treatment on Days 2, 4, 8, and 15 as long as the patient remains hospitalized.
Comments:
The US FDA has issued an Emergency Use Authorization to allow vilobelimab as a treatment for coronavirus 2019 (COVID-19) in hospitalized patients when administered within 48 hours after receiving invasive mechanical ventilatory (IMV) therapy or extracorporeal membrane oxygenation (ECMO). This drug is not approved for this use by the US FDA.
For additional information, visit https://www.fda.gov/drugs/emergency-preparedness-drugs/emergency-use-authorizations-drugs-and-non-vaccine-biological-products.
Use: To treat COVID-19 when administered within 48 hours after receiving IMV or ECM.
What happens if I miss the dose?
You are unlikely to miss a dosage in a medical setting.
What happens if I overdose?
In a medical setting, an overdose is treated immediately.
What should be avoided?
If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.
Interaction with other drug
Other medications, such as prescription and over-the-counter medicines, vitamins, and herbal products, may also affect vilobelimab. Inform your doctor of all the other medications you take.