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Generic name: lidocaine and prilocaine topical [LYE-doe-kane-and-APRIL-oe-kane-TOP-ik-al]

Brand names: agoneaze, Anodyne LPT, Livixil Pak, Priloheal Plus 30, realheal-I, valladerm-90
The class of drug: topical anesthetics

What is Valladerm-90?

Lidocaine and prilocaine can be described as local anesthetics (numbing medications). They function by blocking the signals from your body's nerves.

Valladerm 90 (for the face) is a mixture of medicine that helps to reduce the pain of the skin areas of the penis or vagina. Valladerm 90 is used to help you prepare for small surgical procedures as well as surgical procedures for these locations.valladerm-90 can also be used for other purposes that are not covered in this medication guide.

Side effects of Valladerm-90

See a doctor immediately. If you experience any of the following symptoms that indicate an allergic reaction, an allergic reaction that causes hives; difficulty breathing; and swelling of your lips, face, and tongue.

Valladerm-90 may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • Intense burning, stinging, or irritation at the site where the medication was applied.
  • Redness or swelling;
  • Abrupt dizziness and dizziness or following the application of medicine;
  • Blurred vision, or ringing within your ear;
  • The appearance of purple or bruising the skin
  • Bizarre temperatures and sensations.

Common negative side effects of valladerm 90 could include:

  • Slight burning when the medicine is sprayed;
  • Itching, rash,
  • Change in the color of the skin where the medication was used.

This isn't a complete list of possible side effects, and other side effects could be present. Consult your physician to seek medical advice on the effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.


A high dose of numbing medication can result in death if too much of the medication is absorbed by the skin. Overdose symptoms may include irregular heartbeats, seizures (convulsions) or coma, slow breathing, and the failure of breathing (breathing ceases).

Utilize the smallest amount of valladerm-90 required to numb the skin. Don't apply large quantities of valladerm-90 or cover the affected skin areas with a bandage or plastic wrap without seeking medical advice.

Before you take this drug

You shouldn't make use of valladerm-90 in the event that you are allergic to any kind of numbing medication.

Fatal overdoses have occurred in cases where numbing drugs were administered without consulting a medical professional (for example, during an aesthetic procedure such as shaving off hair with lasers). However, overdoses have occurred in women receiving numbing medication prior to having a mammogram.

Be aware that numerous cosmetic procedures can be done without the involvement of a doctor.

To make sure that valladerm 90 is appropriate for you, consult your physician if you suffer from:

  • A blood cell disorder referred to as methemoglobinemia
  • Liver disease;
  • A genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
  • A genetic history in the family of methemoglobinemia or any other genetic enzyme deficiency

FDA-pregnancy category B. Valladerm-90 isn't expected to harm the unborn baby. Inform your doctor if you are expecting or planning to become pregnant while receiving treatment.

Lidocaine and prilocaine may be found in the breast milk and cause harm to the nursing infant. Notify your doctor immediately if you plan to breastfeed your infant.

How to take Valladerm 90?

Follow all the instructions on the label of your prescription. Do not apply valladerm 90 in greater quantities than what is recommended.You might need to apply valladerm-90 yourself for up to 4 hours prior to the procedure or surgery. You will be provided with specific instructions on how much to apply and how long you should allow it to remain on the skin. Follow these instructions with care. Consult your physician or pharmacist for any additional questions.

Utilize the least amount of medication required to numb the area. Your body may absorb too much medication if you apply too much, especially if you apply it to large areas of skin or apply bandages, heat, or plastic wraps to treatment areas of the skin. Skin that is damaged or inflamed may absorb more topical medicine than healthy skin.

You might have to cover your skin to keep the medication in place. Don't cover the treated area unless your doctor has advised you to.

Follow the dosing guidelines carefully when administering this medication to your child. Doses for valladerm-90 are based on weight gain in children. Do not permit a child to take this medicine without supervision from an adult.Keep the cream at room temperature, far from heat and moisture. Don't allow the cream to cool.

What happens if I miss the dose?

Contact your physician for advice. If you haven't applied valladerm-90 when it is needed prior to surgery or a medical procedure,

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

A high dose of numbing medication could cause fatal side effects if too much of the medicine is absorbed into the skin and into your blood. The symptoms could include irregular heartbeats, seizures (convulsions), slow breathing, coma, and respiratory impairment (breathing ceases).

The application of prilocaine and lidocaine to the skin is not likely to cause overdoses. If you do not apply more than the suggested dosage,

What should be avoided?

Don't let valladerm-90 come into contact with your eyes. Should it happen, wash with water.Do not consume by mouth. Valladerm-90 can only be used to treat skin.

Avoid causing injury to treated areas of the skin while they're in a state of numbness. Avoid contact with extremely hot or extremely cool surfaces.

Interaction with other drugs

Inform your doctor about any medications you are taking or start or stop taking during your treatment with valladerm 90, particularly:

  • Chloroquine, dapsone, nitrofurantoin, isosorbide dinitrate, nitroglycerin, nitroprusside and quinine are antimalarial medications commonly prescribed to patients for multiple medical issues.
  • Heart rhythm medication—amiodarone, dofetilide, dronedarone, mexiletine, sotalol, tocainide, and others;
  • Seizure medicine: phenobarbital, phenytoin, primaquine,
  • A sulfa-based drug, Bactrim, Septra, SMX-TMP, and others

This list isn't exhaustive. Other medications may interfere with lidocaine and topical prilocaine, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions that are not included in this guideline for medication.