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Brand names: Asthmanefrin (Racepinephrine), S2 Inhalant (Nephron), Micronefrin
Dosage form: inhalation solution (2.25%)
Drug class: Adrenergic bronchodilators

What is Racepinephrine?

Racepinephrine works as a bronchodilator. It improves breathing by relaxing the muscles of the airways.Racepinephrine can be used to treat asthma symptoms such as wheezing and shortness of breath.This medication guide does not list all possible uses of racepinephrine.

Side effects of Racepinephrine

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing or swelling of lips, face, tongue or throat. Please seek medical attention immediately.

Racepinephrine can cause serious side effects. If you experience:

  • New or worsening symptoms of asthma
  • Rapid heart rate or tremors;
  • Sleep problems (insomnia);
  • A seizure (convulsions);
  • Anxiety, confusion, and severe chest pain are all signs of dangerously high blood pressure.

There may be other side effects. For medical advice on side effects, call your doctor. Contact the FDA by dialing 1-800-FDA-1088 in order to report adverse reactions.


If you've taken an MAO inhibitor in the last 14 days (such as isocarboxazid or linezolid) or phenelzine rasagiline, selegiline, or tranylcypromine, do not use racepinephrine.

Before you take this drug

You should not use racepinephrine without a confirmed diagnosis of asthma from a physician.If you have an allergy to racepinephrine, do not use it.If you've used an MAO inhibitor in the last 14 days, do not use racepinephrine. It is possible that a dangerous drug interaction will occur. MAO inhibitors are isocarboxazid (linezolid), phenelzine (phenelzine injection), rasagiline (selegiline), methylene blue injection, and others.

If you have any other medical conditions or concerns, ask your doctor if this medication is safe to use.

  • Heart disease
  • High blood pressure
  • Diabetes;
  • A thyroid disorder
  • Mental illness or emotional disorders;
  • Seizures or epilepsy;
  • Narrow-angle glaucoma;
  • An enlarged prostate can cause urination issues.

Racepinephrine is not known to harm unborn babies. If you are pregnant, do not take this medication without consulting your doctor.Racepinephrine is not known to pass into breast milk or whether it can harm a baby who is nursing. If you are breastfeeding a child, do not take this medication without consulting your doctor.This medicine should not be given to children younger than four years of age without consulting a doctor.

How to take Racepinephrine?

Follow the instructions on the label or those prescribed by your physician. Don't take more than recommended. Too much or too frequent use of racepinephrine can increase the risk of a heart attack or stroke. Both can be fatal.Racepinephrine comes as a liquid that is placed in a bulb nebulizer. The nebulizer will release the medication for you to inhale.A child who uses racepinephrine must be under the supervision of an adult.Your symptoms should improve in 20 minutes after using racepinephrine.If your symptoms don't improve after 20 minutes or worsen, call your doctor immediately.Asthma can be treated with a combination of drugs. Follow your doctor's instructions when taking all medications. Each medication comes with a patient instruction guide or medication guide. You should not alter your medication or doses without consulting your doctor.If you feel that your medication is not working properly, seek medical attention.

Asthma symptoms can worsen if you notice:

  • Inhaling more than 12 times in 24 hours
  • Using more than nine inhalations per 24 hours on three or more days within a week
  • Having more than two asthma attacks within a week.

Store away from moisture, light, and heat.Store at room temperature, away from moisture, heat and light.If it appears brown or cloudy, do not use racepinephrine. It is best to throw it away and replace it with a fresh supply of racepinephrine.

Details on dosage

Adult dose for asthma-acute:

A rubber hand-held nebulizer is used to inhale 0.5 mL up to three times. This should not exceed 3 hours.
Maximum dose: 12 inhalations per 24 hours.
Use(s): Temporary relief from mild symptoms of intermittent asthma

Usual pediatric dose for asthma (acute):

For 4-year-olds and older, 1 to 3 inhalations (0.55 mL) via a rubber hand-held nebulizer This should not be done more than three times per day.
Maximum dose: 12 inhalations per 24 hours.
Use(s): Temporary relief from mild symptoms of intermittent asthma

What happens if I miss the dose?

You may not have a schedule for racepinephrine because it is only used as needed. If you have a dosing schedule, take the missed dose immediately after you remember. If your next scheduled dosage is approaching, skip the missed dose. You should not take extra medicine to compensate for a missed dose.Use no more than 12 inhalations in 24 hours.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Avoid getting racepinephrine into your eyes.Avoid consuming or eating products that contain caffeine. This includes coffee, teas, soft drinks, and energy drinks. Caffeine can raise your blood pressure if you're using racepinephrine.

Interaction with other drug

Tell your doctor if you are taking any new medications or if you will stop taking any of your current ones.

  • Other asthma medications
  • Diet pills, stimulants, appetite suppressants, or diet pills
  • A cold or allergy medication that contains a medicine that is a decongestant
  • Antidepressants or medicines to treat mental illnesses.

This list is incomplete. Other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products, may interact with racepinephrine. This medication guide does not list all possible interactions.