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Generic name: [HYE-oh-SYE-a-meen, meth-EN-a-meen, METH-il-een-BLUE, FEEN-il-sa-LIS-il-ate, SOE-dee-um-bye-FOS-fate]hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate monobasic
Names of brands: Phosphasal, Urelle, Uribel, and Urimar-T. Urin D/S…
Classification of drugs: Urinary antispasmodics

What is Uribel?

Hyoscyamine is a chemical that produces a range of effects on the body, such as the relief of muscle spasms.Methenamine and Methylene Blue are mild antiseptics to fight the growth of bacteria that cause urinary tract infections and bladder infections.Phenyl salicylate acts as a mild painkiller.

Monobasic sodium biphosphate is a kind of phosphorus. It is an organic substance that is vital to every cell in our body.

Uribel is a combination medicine that treats bladder irritation (pain spasms, inflammation, and pain) that is caused by urinary tract infections. Uribel can also be utilized to reduce discomfort in the bladder when undergoing a medical procedure.Uribel is also employed for other purposes that are not covered in this guideline.

Side Effects of Uribel

Contact a medical professional immediately. If you are experiencing warning signs of an allergic response, such as hives, difficulty breathing, and swelling of your lips, face, and tongue,

This medication could cause severe adverse consequences. Take this medicine off and consult your physician immediately if you suffer from:

  • Severe dizziness, blurred vision, and a fast heart rate;
  • Difficulty or painful urination and
  • Breathlessness.

Adults who are older may be more likely to experience adverse reactions from this medication.

Methylene blue is likely to cause your stools and urine to appear green or blue in color. This is a typical consequence of the drug and won't cause harm.

Common adverse consequences of Uribel could include:

  • Dizziness, drowsiness;
  • Dry mouth
  • Nausea, vomiting.

This list does not represent all possible side effects; additional ones could occur. Please consult your physician if any adverse reactions appear, and report any to FDA at 1-800-FDA-1088.


A variety of drugs may interfere with methylene blue. When you are taking this medication, you should not discontinue or start using any other medication without consulting your physician.

If you are taking an antidepressant, psychiatric antidepressant, or antidepressant, contact your physician right away if you are experiencing symptoms of a serious drug interaction, such as confusion, memory issues, feeling overly active (mentally and physically), loss of control, muscle spasms, sweating, shivering, diarrhea, or fever.

Before you take this drug

It is not recommended to take this medication if you are allergic to hyoscyamine, methenamine, methylene blue, phenyl salicylate, or sodium triphosphate monobasic.

While you are receiving treatment using this medication, you should not discontinue or start using any other medication unless your doctor has told you to.

To make sure that this medicine is suitable for you, inform your doctor if:

  • Heart disease;
  • A heart rhythm disorder
  • Congestive heart failure;
  • Coronary heart diseases;
  • A heart valve disorder;
  • Glaucoma;
  • An enlarged prostate or bladder obstruction
  • Myasthenia gravis;
  • An ulcer or obstruction inside your stomach.
  • An allergy or sensitivity to belladonna (donnatal and other)
  • Allergies to salicylates (such as aspirin, choline, magnesium trisalicylate, and magnesium salicylate).

It is unclear if this medication could affect a newborn baby. Inform your physician if you are expecting or planning to have a baby while taking this medication.

This medication can be absorbed into the breast milk and could cause harm to a nursing infant. Inform your doctor immediately if you plan to breastfeed your infant.Don't give the medication to a child unless you have medical guidance.

How to take Uribel?

Follow all the instructions on the prescription label. Don't take this medication in greater or lesser quantities or for longer than the recommended time.Drink plenty of fluids while you take this medication.

Hyoscyamine may slow digestion and may take longer before your body is able to take in any medications you consume by mouth.Keep the bottle at room temperature, far from heat, moisture, and light. Make sure the bottle is tightly shut when not being used.

What happens if I miss the dose?

You should take the missed dose as soon as you can remember. Do not take your missed dose if you are nearing the time for the next dose. Don't take any extra medication to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Helpline at 1-800-222-1222.

What should be avoided?

Beware of taking an antacid anti-diarrhea drug within 1 hour prior to or following the time you have taken methenamine, hyoscyamine, methylene blue, phenyl salicylate, and sodium biphosphate monobasic. Antacids or anti-diarrhea medicines can hinder the body's ability to take in hyoscyamine.

If you are also taking ketoconazole (Nizoral), make sure you wait at least two hours following the dose before taking hyoscyamine, methenamine, and methylene blue. Salicylate of phenyl, as well as sodium triphosphate monobasic.

Interaction with other drugs

Many medications can interfere with methylene blue. Discuss with your doctor the other medications you are taking. It may be necessary to stop taking certain medicines (in certain instances, up to five weeks prior to the time you begin the treatment process using Uribel). However, don't discontinue taking any medicines without consulting your physician. This includes:

  • Any antidepressant of any kind;
  • Diet pills, stimulants, diet pills, anti-cold or allergy medications, ADHD medication;
  • Narcotic pain medication
  • Medications used to manage the symptoms of Parkinson's disease (also known as restless leg syndrome),
  • A "triptan" migraine headache

If you are taking any of these medications, taking a medicine that contains methylene blue could result in excessive levels of serotonin throughout your body. Contact your physician immediately in case you are experiencing symptoms of this disorder: anxiety, hallucinations, or fever; rapid heart rate; hyperactive reflexes. Nausea, vomiting, loss of coordination, diarrhea, and falling asleep.

A variety of drugs can interact with this drug. It is not possible to list all the interactions included here. Hyoscyamine may cause problems with the body's ability to take in other drugs you consume by mouth. Discuss with your physician every medication you take and any medication you begin or stop using, including:

  • A diuretic, or "water pill";
  • Medications that alter the acidity in your urine sodium bicarbonate, potassium citrate, and citric acid with sodium or potassium
  • Bladder or urinary medicines—darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;
  • A sulfa drug.

This isn't a complete list, and a variety of other medications can be incompatible with Uribel. This includes prescription and over-the-counter medications, vitamins, and herbal remedies. Provide an inventory of all your prescriptions to any doctor who will treat you.



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