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Targiniq ER

Generical name: naloxone and extended-release tablets of oxycodone
Drug class: narcotic analgesic combinations

What is Targiniq ER?

Targiniq ER is a mix of oxycodone and naloxone. Naloxone can block certain effects of opioids, such as feelings of well-being, which can result in opioid addiction. Oxycodone is an opioid medication. Sometimes, opioids are referred to as narcotics. Targiniq Er is used for 24/7 treatment of extreme pain that isn't managed by other medications. Naloxone is incorporated into this medication to stop misuse of the narcotic component. Targiniq Er is not recommended and is intended to be used on an ad-hoc basis to treat pain that is not 24/7.


It is not recommended to use Targiniq ER if your condition is respiratory problems or asthma that are severe, liver diseases that are severe, or an obstruction in your stomach or your intestines. Oxycodone can slur or even slow your breathing. Avoid using this medication in large amounts or for longer than the time prescribed. Inhale the tablet completely to prevent exposure to a fatal dose. Targiniq ER could cause addiction even when taken in regular doses. Don't share this medication with anyone else, particularly one who has a history of substance abuse or addiction. Place the medicine in a location where others aren't able to access it.

The misuse of opioid medications may result in an overdose, addiction, or the death of a child or another person who is taking the medication without a prescription. Inform your doctor when you're pregnant. Oxycodone could cause withdrawal symptoms that could be life-threatening for newborn babies in the event that the mother took the medication during pregnancy. Certain medicines may interact with oxycodone and naloxone and can cause serious adverse effects or even the death of a patient. Tell your doctor about all the medications you are currently taking and any you begin or stop taking. Avoid drinking or consuming alcohol. Dangerous side effects or even death could happen.

Before taking this medication

It is not recommended to use Targiniq ER in the event that you are sensitive to oxycodone or naloxone or suffer from:

  • Serious asthma or breathing issues;
  • Severe liver disease severe liver disease
  • A blockage in your stomach or the intestines.

Certain medicines may react with oxycodone, causing an extremely serious condition known as serotonin syndrome. Make sure that your doctor is aware whether you are also taking medication to treat mental illness, depression, such as Parkinson's disease, chronic infections, migraines, or to prevent vomiting and nausea. Consult your physician prior to making any changes to how or when you take your medication.

To ensure that Targiniq ER is suitable for you, inform your physician if you have:

  • Any kind of breathing problem or lung disease.
  • An injury to the head or brain tumours; seizures or brain tumours;
  • An antecedent history of abuse of drugs, alcohol dependence, or mental illness
  • Problems with urination;
  • Kidney or liver disease;
  • Heart disease;
  • Issues with your gallbladder, thyroid, pancreas, or gallbladder
  • If you are using a sedative such as valium (diazepam, alprazolam, or lorazepam), ativan, klonopin, restoril, tranxene, versed, xanax, and many others,

It is not clear if Targiniq ER can cause harm to a baby who is not yet born. If you take this medication during your pregnancy, the baby may become dependent on oxycodone. It can trigger severe withdrawal symptoms in the newborn after it's born. Babies who are dependent on habit-forming medications could require medical intervention for a period of time. Consult your physician if you are expecting or plan to be pregnant.

Oxycodone may be absorbed in breast milk and cause harm to a nursing infant. It is not recommended to breastfeed while you're using Targiniq ER.

Similar or related drugs

aspirin, acetaminophen, tramadol, naproxen, oxycodone, and tylenol

How to take Targiniq ER?

Take Targiniq exactly as directed by your physician. Follow the instructions on the prescription label. Oxycodone could cause breathing to stop or slow down, particularly when you begin taking this medication or if you change your dosage. Do not use Targiniq ER in greater amounts or for a longer duration than the recommended time. Inform your doctor if the medication seems to stop functioning as well as relieving the discomfort.

Oxycodone could become habit-forming even when taken in regular doses. Don't share this medicine with a person you know, particularly one with a history of addiction or abuse. Misuse of NARCOTIC MEDICINES CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in children or others who take the medication without a prescription. Selling or giving away Targiniq ER is illegal. Avoid crushing, chewing, or breaking the Targiniq ER extended-release tablet. Inhale it completely to prevent exposure to a fatal dose. Targiniq is typically used every twelve hours. The medicine should be taken at the same time every day.

Do not stop taking TarginiqER at the same time after prolonged use, or you may suffer from uncomfortable withdrawal effects. Consult your doctor about how to prevent withdrawal symptoms after you stop taking Targiniq ER. Never break or crush the Targiniq pill in order to inhale it or mix it with a liquid that allows you to inject it into your vein. This can lead to deaths due to the use of oxycodone and other prescription drugs. Keep the items at room temperature and away from moisture, heat, and light.

Make a note of the quantity of medicine consumed from each new bottle. Oxycodone is a substance that is abused, and you must be aware of any person who is taking your medication improperly or without a prescription. Do not store any leftover Targiniq tablets for use in the emergency room. Consult your pharmacist on how you can find a drug disposal program. If there's no take-back plan, flush any empty tablets into the toilet. The flushing of medications is recommended to decrease the risk of accidental overdoses that can cause death. This recommendation is applicable to only a small amount of drugs. The FDA, in conjunction with the company, decided this is the most efficient method of disposal and poses the lowest danger to the safety of humans.

What happens if I miss a dose?

Because Targiniq ER is a medication used to treat pain, you're not likely to skip a dose. Avoid any missed doses when it's almost time to take your next dose. Don't take extra medication to replace the missed dose.

What happens if I overdose?

Get medical attention immediately or contact the poison help line at 1-800-222-1222 for help. A Targiniq overdose in the ER is fatal, especially for children or any other user of the medicine without a prescription.

The symptoms of an overdose can include extreme tiredness, weak or limp muscles, clammy and cold skin, bright pupils, diminished consciousness, a low pulse, or slow breathing (breathing could be stopped).

Avoid this

Don't drink alcohol. Dangerous side effects or death may occur when alcohol is mixed with Targiniq ER.

The medication could affect your ability to think or react. Avoid operating machinery or driving until you understand the extent to which Targiniq ER can affect your health. Drowsiness or extreme drowsiness could result in accidents or falls.

Side effects of Targiniq ER

Take immediate medical attention if you notice any of the following symptoms warning of an allergic reaction: hives; feeling faint; chest pain; and rapid heartbeats. It can cause difficulty breathing or swelling of your lips, tongue, throat, or face. As with other narcotic medications, oxycodone is a narcotic medicine that can slow the rate of breathing. The risk of death can occur when breathing becomes weak.

Contact your doctor immediately if you are suffering from:

  • Breathing shallowly, slow heartbeat, cool, clammy skin;
  • Seizure (convulsions);
  • Confusion, severe drowsiness;
  • A lightheaded sensation, similar to feeling like you're about to pass out.
  • Infertility, missed menstrual periods;
  • Inability to sex, sexual problems, or a loss of interest in sexual sex and
  • Low levels of cortisol cause nausea, loss of appetite, vomiting, dizziness, a rise in tiredness, or weakness.

Get medical attention immediately. If you experience signs that suggest serotonin syndrome, for example, hallucinations, agitation, sweating or shivering, an increase in heart rate, stiffness of muscles and twitching, loss of coordination, nausea, vomiting, or diarrhoea,

Targiniq E.R. is more likely to trigger breathing problems in elderly adults as well as those who are sick, malnourished, or otherwise weak.

Common side effects of Targiniq ER include:

  • Drowsiness, headache, and dizziness;
  • Stomach pain, nausea, and constipation;
  • Anxiety or
  • Sweating.

This isn't a complete list of all the side effects. Other effects may also be present. Consult your physician to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Sometimes it's not recommended to take specific medications together. Some drugs can cause a rise or a decrease in levels of oxycodone in your blood, which can trigger side effects or render the drug less effective. Oxycodone can also affect the blood levels of some other medications, making them less effective or worsening their consequences. Narcotic (opioid) medication may mix with a variety of other drugs and trigger dangerous adverse effects or even death. Check with your physician whether you are also taking:

  • Other narcotic medicines other narcotic medications—opioid pain medicine, prescription medicine for cough;
  • substances that cause you to sleep or cause breathing to slow, such as a sleeping pill, muscle relaxant, sedative tranquillisers, or antipsychotic drug; or
  • The drugs you take affect the serotonin levels in your body. Medications for Parkinson's disease, depression, migraine headaches, serious infections, or the prevention of vomiting and nausea

The list below is not comprehensive. Other drugs can be incompatible with oxycodone and naloxone, such as prescription and over-the-counter medications, vitamins, and herbal remedies. The interactions of all potential types aren't included in this guide to medications.