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What is Sutimlimab?
Sutimlimab helps treat hemolysis (the breakdown of red blood cells) in adults suffering from cold agglutinin disorder (CAD). Sutimlimab can also be employed for other purposes that are not covered in this guideline.
Side effects of Sutimlimab
See a doctor immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and throat.
There are some side effects that can happen during an injection. Inform your physician when you feel nauseated, dizzy, lightheaded, or sweaty. or experience headaches, chest tightness, back discomfort, breathing difficulties, or swelling on your face.
Sutimlimab may cause serious side effects. Consult your doctor immediately in the event that you experience:
- Joint discomfort as well as swelling, itchy skin on the nose and cheeks, and an unprovoked temperature;
- Symptoms of red blood cell breakdown—tiredness, shortness of breath, rapid heart rate, blood in your urine or dark urine; or
- Symptoms of an indication of an infection include fever and severe headaches with stiff back or neck symptoms. Other symptoms of an infection include painful urination, urinating more frequently than normal, coughing or breathing problems, symptoms akin to flu symptoms, or redness, pain, or swelling in the area.
Common negative side effects of sutimlimab include:
- Diarrhea, indigestion;
- The respiratory tract (or an infection caused by viruses);
- Symptoms of a cold like nasal stuffiness, sneezing, sore throat, cough,
- Joint pain, inflammation, or discomfort; or
- Inflammation of the lower leg, the ankles, feet, and lower legs.
This is not a comprehensive list of possible side effects, and others could happen. Contact your doctor to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.
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Warnings
You should be vaccinated at least two weeks prior to your start of treatment with sutimlimab. It is possible that you will need additional vaccines while you are treated with sutimlimab.
Contact your doctor immediately. If you are suffering from signs of infection such as fever, a severe headache that causes stiff back or neck pain in urination, having to urinate more frequently than normal, coughing, or breathing problems, symptoms that are similar to the flu, or redness, pain, and swelling on the face,
Before taking this medication
It is not recommended to take sutimlimab if you have an allergy to any of its components.
Speak to your doctor if you have ever suffered from:
- human immunodeficiency virus (HIV);
- Hepatitis B and C
- If you are suffering from an infection or fever,
- If you have an auto-immune illness, such as Lupus.
Sutimlimab could reduce your immune system's strength and affect the body's ability to fight diseases. Consult a doctor about the risk you face based on your personal situation.
Discuss with your physician if you are expecting or planning to become pregnant or if you plan to breastfeed.
How to take Sutimlimab?
Follow the directions on the prescription label and review all medication guides and instructions. Follow the medication exactly as prescribed. Sutimlimab is administered into a vein by a doctor. Sutimlimab is typically administered within 1 to 2 hours.It is typical to receive an initial dose of sutimlimab. This is followed by a second dose a week later. Two weeks after the second dose, you'll receive a dose every two weeks.
The doctor will monitor you for between 1 and 2 hours to ensure that you don't have an allergic reaction.You will be monitored closely once you have stopped taking sutimlimab. If you suffer from CAD, stopping this medication could cause the destruction of your red blood cells. It is recommended to be vaccinated at least two weeks prior to the start of your sutimlimab treatment. It is possible that you will need additional vaccinations while you are treated with this medication.
Details on dosage
Usual Adult Dose for Hemolytic Anemia:
Recommended dosages are dependent on body weight.
From 39 to less than 75 kg 6500 mg IV
A weight of 75 kilograms or greater 75 kg or more: 7500 mg IV
Comments:
It is recommended to treat each week for the first two weeks, and then every two weeks after that.
It is suggested to administer treatment according to specific dosage times or within two days of these times.
Use: To lessen the requirement for RBC transfusions because of hemolysis in adult patients with cold agglutinin disorder (CAD).
What happens if I miss a dose?
Consult your physician for the appropriate treatment in the event that you don't make an appointment to receive the sutimlimab injection.
What happens if I overdose?
In a medical facility, an overdose could be immediately treated.
What should be avoided?
Follow your doctor's advice regarding any limitations on foods, drinks, or any activity.
Interaction with other drugs
Other drugs can interact with sutimlimab, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your physician about any other medications you are taking.