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Sumatriptan (oral/nasal)

Generic name: sumatriptan (oral or nasal) [soo-ma-TRIP-tan]
The brand names are: Imitrex, Imitrex Nasal, Onzetra Xsail, and Tosymra.
Dosage forms: nasal capsule (11 mg), nasal spray (10 mg/inh; 20 mg/inh; 5 mg/inh), oral tablet (100 mg; 25 mg; 50 mg).
Drug class: Antimigraine agents

What is Sumatriptan?

Sumatriptan is a headache medication that narrows blood vessels in the brain. Sumatriptan can also lower the levels of certain substances that can cause headache pain, nausea, sensitization to sound and light, and other migraine-related symptoms. Sumatriptan can be used for migraine treatment in adults. Sumatriptan can only relieve headaches. It will not stop headaches or decrease the frequency of attacks. Sumatriptan is not recommended for treating a commonly occurring tension headache or headache that results in an inability to move on the opposite side. Make sure to only take this medication when your symptoms have been identified by a physician as migraine-related headaches. Sumatriptan is also employed for reasons not mentioned in this guide to medication.

Side effects of Sumatriptan

Seek medical attention immediately in the event that you exhibit symptoms that indicate an allergy, such as asthma, hives, and swelling of your lips, face, and tongue.

Sumatriptan may cause serious side effects. Stop taking sumatriptan immediately and contact your doctor immediately if you experience:

  • Acute stomach pains and bleeding vomiting;
  • Intense chest pains, shortness of breath, abnormal heartbeats, severe chest pain;
  • A seizure (convulsions);
  • Intense headache with fuzzy vision and pounding in your neck or in your ears;
  • Blood circulation issues in your feet or legs—cramps and tightness, a heavy feeling, tingling or numbness, muscle weakness, burning pain, a cold sensation, changing color (pale or blue), and hip pain
  • Heart attack symptoms: chest pressure or pain; pain expanding into your shoulder or jaw; vomiting; sweating;
    serotonin levels that are elevated in the body can cause the body to experience agitation, hallucinations, fever, sweating, shivering, rapid heart rate, muscle stiffness, loss of coordination, twitching, vomiting, diarrhea, or
  • Symptoms of signs of stroke—sudden weakening or numbness (especially on the opposite part of your body) as well as sudden, extreme headaches, speech lisping, or issues with balance or vision.

Common side effects of sumatriptan include:

  • Discomfort or tightness in your throat, chest, or jaw.
  • You feel a sense of pressure or discomfort anywhere on your body.
  • Sensation of tingling or numbness, hot or cold
  • Dizziness, drowsiness, weakness;
  • A distinct or unpleasant taste is present in your mouth following the use of the nasal medication.
  • Discomfort, burning, numbness, or tingling sensations in your throat or nasal area after taking the nasal medication or
  • Nose that is stuffy or swollen after taking the nasal medication.

This isn't an exhaustive list of possible side effects, and other effects may also be present. Consult your physician to seek medical advice on adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

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Warnings

Sumatriptan should not be used when you suffer from insufficiently controlled hypertension and heart conditions, certain heart rhythm issues, or an underlying history of heart attacks and strokes, as well as circulatory issues that lead to a shortage of blood flow in the body.

Do not take this medication if you've used an MAO inhibitor in the last 14 days, including linezolid, isocarboxazid, methylene blue injection, or phenelzine, rasagiline, and selegiline. tranylcypromine.

Sumatriptan should not be used within 24 hours prior to or following another migraine medication.

Before taking this medication, you must consult your physician.

It is not recommended to use sumatriptan if you have an allergy to it or have ever experienced:

  • Heart issues or stroke (including "mini-stroke");
  • Coronary artery diseases, angina (chest pain), blood circulation issues, and the inability of blood flow for the heart
  • circulation problems affecting your legs, arms, stomach, intestines, or kidneys;
  • A heart disorder called Wolff-Parkinson-White syndrome;
  • Uncontrolled high blood pressure
  • Serious chronic liver illness or
  • A headache that is distinct from the usual migraine headaches.

Don't take sumatriptan if you have taken an MAO inhibitor within the past 14 days. A potentially dangerous interaction between drugs could occur. MAO inhibitors are isocarboxazid, linezolid, Methylene Blue injection, rasagiline, phenelzine, tranylcypromine, and others.

Make sure to inform your doctor whether you are also taking stimulant medications, opioid medicines, herbal products, or medications that treat depression, mental illness, Parkinson's disease, serious infections, or to prevent nausea or vomiting. These medications can interact with sumatriptan to cause an extremely serious condition known as serotonin syndrome.

Speak to your doctor if you are ever diagnosed with:

  • Kidney or liver disease;
  • Epilepsy or any seizure disorder
  • Hypertension, a heart rhythm disorder, or
  • Risk factors that can lead to coronary artery diseases (such as menopausal symptoms, diabetes, smoking, obesity, diabetes, being high in blood pressure and cholesterol, having an ancestral connection to coronary disease, or being over 40 and male)

It isn't known if this medication will cause harm to a baby who is not yet born. Consult your physician if you are expecting or planning to become pregnant. It is not recommended to give birth within 12 hours after taking sumatriptan. If you use an infant pump during this period, you should throw away any milk you can collect. Don't give it to your infant. Sumatriptan is not recommended for use by anyone younger than

How to take sumatriptan?

Apply sumatriptan immediately if you experience headache-related symptoms. Follow the instructions on the label of your prescription and also read the medication guide or instructions sheets. Make sure you use the medicine exactly as prescribed. The first dose is given at the clinic or in a hospital setting to treat any adverse reactions. Take note of and follow the instructions that are included with your medicine. Talk to your pharmacist or doctor if you don't understand these directions.

Take one sumatriptan tablet in its entirety with a full bottle of fluid. Do not cut the tablet. Do not take a sumatriptan capsule for the nose by mouth. It is only for use inside your nasal-inhaler system that comes with sumatriptan. After taking sumatriptan, if your headache does not disappear or disappears only to return, then take a dose again in the event that it's been at least two hours since the first dose.

Don't exceed the recommended dosage. Too much migraine medication can cause more headaches. Talk to your doctor if medicine isn't functioning as effectively for treating migraine headaches. Contact your physician if symptoms do not improve or if there are more than four headaches in the course of a calendar month (30 days). Keep sumatriptan in a cool, dry place free of heat, moisture, and light. Don't store it in an airtight container. Don't store it in the freezer.

What happens If I miss a dose?

Because sumatriptan is only used in the event of need, the medication does not require a daily dose schedule. Consult your doctor if symptoms don't improve after taking this medication.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

Overdose symptoms can include tremors, redness of the skin in your legs or arms, weakness in coordination, breathing difficulties, blue-colored lips and fingernails, visual problems, or a seizure (convulsions).

What should be avoided?

Do not take sumatriptan in the 24 hours preceding or after taking another migraine medication, such as:

  • Sumatriptan injection, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, zolmitriptan, or
  • Ergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.

Avoid driving and other hazardous activities until you understand how sumatriptan affects your body. Your reaction could be affected.

Interaction with other drugs

Discuss with your doctor your other medications, particularly any antidepressants. Other medications can influence sumatriptan, such as medications that are prescribed and available over the counter, vitamins, and herbal supplements. Inform your doctor about all the medicines you are currently taking and any medications you begin or stop taking.

 

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