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Sulfur Hexafluoride

Generic name: sulfur hexafluoride [SUL-fur-HEX-a-FLOR-ide]
The brand name is Lumason.
Formulation for dosage: intravenous powder for injection
Drug class: diagnostic radiopharmaceuticals

What is Sulfur hexafluoride?

Sulfur hexafluoride can be described as a contrast agent utilized to enhance the quality of ultrasound. ultrasonic. Sulfur hexafluoride is used to permit certain parts of the liver, heart, or urinary tract to be clearly observed through an ultrasound. Sulfur hexafluoride can be used for other purposes that are not covered in this guide.

Side effects of Sulfur hexafluoride

Contact emergency medical assistance. If you are experiencing symptoms that are warning signs of an allergic reaction, skin redness, hives, or rash; numbness, warmth, or tingling; difficulty breathing; the feeling of tightness in your throat; or swelling of your lips, face, and tongue.

In rare cases, fatal reactions can occur shortly after or during the injection. Inform your healthcare providers immediately if you experience:

  • The sensation of being light-headed as you're about to pass out.
  • Severe dizziness or a cold sweat;
  • Discomfort in the chest, wheezing, and trouble breathing
  • Rapid or slow heartbeats;
  • A seizure;
  • Extreme headache severe headache, blurred vision, the pounding of your neck or in your ears severe headache, blurred vision, or pounding in your neck or ears
  • Low heart rate and a weak pulse, or a weak breath that is shallow.

Common adverse effects of sulfur hexafluoride could be:

  • Nausea;
  • Headache;
  • Changed taste perception;
  • Getting hot, feeling hot,
  • Discomfort or a warm sensation when the medication is injected.

This isn't a complete list of all the side effects. Other side effects could occur. Consult your physician for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

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In rare instances, serious or fatal reactions can occur shortly or immediately after the injection. Inform your healthcare providers immediately if you feel dizzy or short of breath, if you experience chills or chest pain, a severe headache, rapid or slow heartbeats, or if you feel a pounding sensation in your neck or ear.

Before taking this medication

You shouldn't be treated with sulfur hexafluoride if you have an allergy to it.

Inform your doctor if you were ever diagnosed with:

  • Heart conditions, like heart problems such as heart attacks or congestive heart failure;
  • A genetic heart defect (especially a condition known as "cardiac shunt");
  • A lung disease that has recently gotten worse.

Consult your physician if you are breastfeeding or pregnant.

How to take sulfur hexafluoride?

To check the liver or the heart, sulfur hexafluoride solution is administered by infusion to the vein.

For a thorough examination of your bladder's condition, sulfur hexafluoride has been injected directly into the bladder via a catheter that is inserted in the urethra (the tube used to pass urine through the bladder).

Your heart rate as well as blood pressure, breathing rate levels, oxygen levels, and other vital indicators will be closely monitored for a minimum of 30 minutes following receiving sulfur hexafluoride. This is to ensure you don't suffer from any allergic reactions to this medication.

Details on dosage

Usual Adult Dose for Diagnostic:

For intravenous injection:
Echocardiography 2 mL of blood as an injection into the IV
Ultrasonography of the lungs: 2.4 milliliters for an injection into the IV

Reconstitute prior to administration; refer to the manufacturer's information on the product.
may repeat dose one time during a single examination.
Follow each injection with one IV flush of 5 mL of 0.9 percent sodium chloride.
Avoid intra-arterial injection.

to opacify the left ventricle chamber and enhance the definition of the left-ventricular endocardial boundary for patients with suboptimal echocardiograms
To identify and localize liver focal lesions using ultrasonography

Usual Pediatric Dose for Diagnostics:

For intravenous injection:
Echocardiography: 0.03 milliliters/kg for an injection, up to 2 mL for each injection.
The liver is ultrasonographically examined at 0.03 mg/kg by IV injection up to a maximum of 2.4 milliliters per injection.
Ultrasonography in the Urinary Tract: 1 mL following reconstitution (the bladder may be filled with a 0.9 percent sodium chloride injection to complete another cycle of voiding and imaging without the necessity of a second dose of the medication).

Reconstitute prior to administration; check the manufacturer's product details.
Follow each injection by one IV flush of 0.9 0.9% sodium chloride.
Avoid intra-arterial injection.

To opacify the left ventricular chamber and enhance the definition of the left-ventricular endocardial boundary in patients who have suboptimal echocardiograms.
To locate and identify hepatic focal lesions using ultrasonography
To determine the severity of vesicoureteral reflux using ultrasonography in infant patients.

What happens If I miss a dose?

Since it is administered by ultrasound, it does not have a regular dosing schedule.

What happens if I overdose?

Because this medication is administered by a health expert in a medical environment, it is highly unlikely for an overdose to occur.

What should be avoided?

Follow your doctor's advice regarding any restrictions regarding food, drinks, or any activity.

Interaction with other drugs

Other medications can influence sulfur hexafluoride. These include medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your physician about all the medications you currently use and any medications you begin or stop taking.