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Generic name: Pilocarpine (oral) [PYE-loe-KAR-peen]
Drug class: Cholinergic agonists

What is Salagen?

Salagen influences the nervous system and boosts saliva secretion in the mouth.Salagen serves to manage dry mouth caused by Sjogren's syndrome or radiation treatment for neck and head cancer.Salagen could be used for other purposes not covered in this medication guide.

Side effects of Salagen

Contact a medical professional immediately. If you experience any of the following symptoms, warning signs of an allergic reaction include: hives; trouble breathing; or swelling of your lips, face, and tongue.

Salagen may cause serious side effects. Stop using Salagen immediately and consult your physician immediately in the event that you experience:

  • Breathlessness;
  • Either a fast or a slow heart rate,
  • Extremely severe headache that is pounding your neck or in your ears;
  • Shaking, confusion,
  • Feeling lightheaded, as if you're about to pass out.

Common side effects of Salgen could include:

  • Increased sweating increased sweating and more frequent urination than normal;
  • Chills, or flushing (warmth or redness, or sensation of tingling);
  • Headache, dizziness, weakness;
  • Nausea, vomiting, diarrhea;
  • Eyes that are blurred, eyes with watery lenses,
  • Nasal runny.

It's not a comprehensive listing of all possible adverse reactions, as other reactions could be experienced. Seek advice from your doctor for medical advice regarding adverse reactions. It is possible to report any symptoms to the FDA by calling 1-800-FDA-1088.


It is not advised to take Salagen in the case of small-angle glaucoma or asthma that is not treated or controlled.

Before you take this drug

Salagen is not a good choice. If you are allergic to it or suffer from any of the following:

  • Untreated, uncontrolled, or untreated asthma
  • Narrow-angle glaucoma.

To ensure that Salagen is suitable for you, inform your doctor that you suffer from:

  • Asthma, chronic bronchitis, chronic obstructive respiratory illness (COPD), or any other breathing disorders;
  • Vision problems or glaucoma
  • Liver disease;
  • Kidney disease;
  • Coronary disease;
  • Gallbladder issues;
  • Mental illness;
  • If you are taking blood pressure or heart medication,
  • If you take a bronchodilator to treat a breathing disorder,

FDA pregnancy category C. It's not clear whether Salagen can affect a newborn baby. Inform your doctor if you're expecting or planning to become pregnant while taking Salagen.

It is unclear if pilocarpine gets into breast milk or whether it can harm a nursing infant. Do not breastfeed when taking this medication.

How to take Salagen?

Follow the directions on the prescription label. Don't take this medication in smaller or larger doses or for longer than the recommended time.You can consume Salagen in combination with food or not.

Drink plenty of fluids when you take Salagen. The medicine may cause more sweating, and you could become dehydrated quickly.Make sure to use Salagen frequently to reap maximum benefits. Refill your prescription prior to running out of medication completely.Keep it at room temperature, far from heat and moisture.

Do I be concerned if I miss a dose?

Take the missed dose as fast as you remember. Avoid your missed dosage if you are nearing the time for the next dose. Don't take any extra medication to make up for the missed dose.

What will happen if I take excessively?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222. A high dose of Salagen could be fatal in extremely large doses.

What should be avoided?

Salagen can create blurred eyes, particularly at night or in low light. Be aware if you drive or engage in any activity that requires you to have clear vision.

Be aware of the dangers of becoming too hot during exercise or in hot temperatures. Salagen could increase sweating and increase your risk of becoming vulnerable to dehydration.

Interaction with other drugs

Other drugs can interfere with pilocarpine. This includes prescription and non-prescription medicines, vitamins, and herbal products. Inform your health professionals about any medications you take currently and all medicines you stop or start using.



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