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Generic name: cyclopentolate and phenylephrine ophthalmic [SYE-kloe-PEN-toe-late-and-FEN-il-EFF-rin-off-THAL-mik]
Drug class: Mydriatics

What is Cyclomydril?

Cyclopentolate the muscles of your eye, causing them to expand (widen) the pupil. Phenylephrine Phenylephrine is a vasoconstrictor that shrinks blood vessels. Cyclomydril (for the eyes) is a mixture of medicine that is used to dilate your pupils prior to an eye examination. Cyclopentolate and phenylephrine can also be used for reasons not covered in this guide.

Side effects of Cyclomydril

See a doctor immediately. If you notice any of the following symptoms, warning signs of reactions to an allergen, such as hives: difficulty breathing and swelling of your lips, face, and throat,

Cyclomydril may cause serious side effects. Contact your physician immediately in the event that you experience:

  • Tunnel vision blurred, distorted, or seeing halos of light;
  • Eye discomfort;
  • Rapid heart rate extreme headache the pounding of your neck or ear, anxiety;
  • Fever;
  • Very little or no urine;
  • Flushing (warmth, redness, warmth, or tingly sensation);
  • Extreme constipation severe constipation
  • Breath is weak or shallow.

Children and infants are more likely to suffer negative effects due to cyclomydril. Discuss with your doctor if the child is suffering from:

  • The confusion, the changes in behavior, hallucinations, confusion;
  • Difficulties with speech, difficulty in recognizing people
  • Anxious or restless behavior;
  • Balance loss or coordination
  • Seizure (convulsions); or
  • Issues with feeding or an inability to eat.

Common adverse effects of cyclomydril could include:

  • Dry mouth or nose;
  • Reduced sweating decreased sweating
  • Sensitivity to the sun

This is not a comprehensive list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.


It is not recommended to take Cyclomydril when you've not treated narrow-angle glaucoma.

Prior to use this drug

You shouldn't take this medication if you are allergic to phenylephrine or cyclopentolate (phenylephrine acts as a decongestant in a variety of medications for sinus infections and sinus medications) or suffer from:

  • Untreated or uncontrolled narrow-angle glaucoma that is untreated or uncontrolled

To ensure that cyclopentolate and phenylephrine are not harmful to you, consult your physician if you suffer from:

  • Glaucoma;
  • Heart disease;
  • Hypertension or
  • Thyroid disorders are a common problem.

FDA classification for pregnant women: It isn't known whether phenylephrine and cyclopentolate will affect a baby who is not yet born. Consult your physician about what you are expecting. It is unclear if it is possible to introduce phenylephrine and cyclopentolate into breast milk or if it is harmful to the nursing infant. Consult your physician if you are breastfeeding a baby.

How to take Cyclomydril?

Cyclomydril is a drop for the eye that is inserted into two or one eye. A doctor will put drops inside your eye.

Inform your doctor immediately in case you experience intense burning, stinging, or irritation to your eyes.

Once the drops are put within your eyes, you can gently apply your finger to the inside corner of your eye for about 2 to 3 minutes to stop the liquid from leaking out into the tear duct. This can help stop your body from taking in too much of this medication. Don't rub your eyes.

If a child is treated with this medication, be sure not to allow the child to touch or rub the eyes. Keep an eye on the child for at least 30 minutes after the eyes drops are put in the . This is to ensure that the medication does not cause serious adverse effects due to its absorption by the tear duct.

Clean your hands after you've touched your eyes. If any of this medication is absorbed by a child's hands, clean them using detergent and soap. This can prevent any medication from accidentally getting into a child's mouth.

What happens if I miss the dose?

Since you'll receive phenylephrine and cyclopentolate in the context of a clinical environment, you're not likely to skip the dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Avoid exposure to the sun or sunlamps, as well as tanning beds, for the duration of several hours after treatment with Cyclomydril. A dilated pupil can cause your eyes to be more sensitive to sunlight. Wear sunglasses to protect your eyes when you're in bright light. Be aware when you drive or engage in any activity that requires that you be conscious as well as able to read clearly. Do not put this medication in your mouth. If this happens, you have a problem. Wash your mouth with water. Beware of feeding your child for at least four hours following the time when the child is treated with cyclopentolate or phenylephrine.

Interaction with other drugs

It is unlikely that any other medication that you inject or take orally can affect the phenylephrine and cyclopentolate that are used to treat eye problems. However, many medicines may interact with one another. Be sure to inform your healthcare professionals about all medications you take, including prescription and non-prescription medicines, vitamins, and herbs.