What is Rhogam?
Rhogam, a sterilized blood solution, is made of human blood. Most people (Rh positives) have Rh in their blood, but others (Rh negatives) don't. Rh-negative people can be exposed by a mismatched transfusion or through pregnancy when the baby is of the opposite blood type. This exposure will cause the Rh-negative blood to produce antibodies that try to destroy Rh-positive blood cells. It can lead to medical complications such as low red blood cells, kidney failure, or shock.rhogam prevents an immune reaction to Rh-positive blood when people with Rh-negative blood types are exposed to it. This medicine can also be used to treat immune thrombocytopenic purpura (ITP).rhogam can be used in other ways not mentioned in this guide.
Side effects of Rhogam
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: skin rash, hives, feeling lightheaded, chest pain, difficulty breathing, swelling of your lips, face, tongue, or throat.
Rhogam can cause serious side effects. If you experience:
- Fever; backache; HTML2_ unusual weakness HTML2_;
- Dark urine, pale or yellow skin;
- Rapid breathing, rapid heartbeat, confusion, feeling of shortness of breath
- Signs of kidney failure include swelling, little or no urination, and rapid weight gain.
- Signs of a blood clot include sudden numbness, weakness or slurred words, difficulty with vision, balance, or chest pain. Other symptoms are coughing and swelling in the legs with redness.
Some of the common side effects associated with rhogam include:
- Nausea, diarrhea, vomiting, and stomach pain;
- Headache, dizziness;
- Weakness, general feeling of ill-feeling, drowsiness;
- Joint or muscular pain
- Flushing (warmth, redness, or tingly sensation);
- Itching on the skin or mild
- Increased sweating
- Pain or tenderness at the injection site.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Similar/related drugs
Nplate, Promacta, Tavalisse, Doptelet, Prednisone, Dexamethasone, and Triamcinolone
Warnings
Rhogam should not be given to patients with hemolytic anemia or immune globulin A deficiency.RHO(D), an immune globulin, can cause a breakdown of red cells. This can cause life-threatening blood or organ failure.If any of these symptoms exist, seek medical assistance immediately. Fever, chills, or back pain Pale skin or red urine. Feeling short of breath.
Before you take this drug
If any of the following apply to you:
- Immune globulin A deficiency (iga), with antibodies to iga
- Hemolytic anemia occurs when there are insufficient red blood cells.
Tell your doctor about any of the following to ensure that rhogam will be safe for you:
- Anemia history;
- Heart diseases, or a family history of coronary arterial disease;
- A bleeding disorder, such as hemophilia;
- High triglycerides
- Kidney disease
- Diabetes.
Rhogam can be used before and after pregnancy. This medication is not known to be harmful to the baby while pregnant or breastfeeding.Tell your doctor that you plan to get pregnant or are pregnant if this medication is prescribed to treat an incorrect blood transfusion.You must inform your doctor if you are Rh-negative or if you've ever received Rh-positive blood during your lifetime. This can include exposure through a mismatched transfusion or even exposure during your first pregnancy. It is important that you tell your doctor about any exposure to Rh-positive blood in the past. This includes mismatched transfusions or even an earlier pregnancy.rhogam (a component of human blood plasma) may contain viruses or other infectious agents. The plasma donated is treated and tested to reduce the possibility of it being infected, but it is still possible that it may transmit a disease. Speak to your doctor about any risks or benefits associated with using this medication.
How to take Rhogam?
Rhogam can be injected directly into a vein or muscle. This injection will be given in a hospital or clinic setting.After receiving immune globulin, your vital signs, such as breathing, blood pressure, and oxygen levels, will be closely monitored. You may need to have your urine tested every 2 to 3 hours for at least eight hours.rhogam can be given to pregnant women at regular intervals in the final half of pregnancy and after delivery.The medicine is administered when the symptoms of an allergic reaction (the body producing Rh antibodies) appear.You may need to have frequent blood tests to ensure that this medication is helping you. Your doctor will determine the length of treatment based on your blood tests, even if you don't notice any changes in your symptoms.rhogam may cause false lab results for glucose in the blood. Inform any doctor that treats you about the use of this medication.
What happens if I miss the dose?
If you are unable to attend your rhogam appointment, call your doctor and ask for instructions.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
After treatment with rhogam, do not receive any "live" vaccines for at least three months. During this period, the vaccine may not be as effective, and you may not be fully protected from disease. Live vaccines are available for measles (MMR), rubella, typhoid (typhoid), yellow fever (yellow fever), varicella, chickenpox, zoster, and influenza (nasal flu).
Interaction with other drug
Other drugs, such as vitamins and herbal remedies, may also interact with RHO(D) immunoglobulin. Inform your healthcare providers of all the medicines you are taking and those you plan to take.
