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Generic name: moxifloxacin (oral/injection) [moxi-FLOX-a-sin]
Drug class: Quinolones

What is Avelox?

Avelox is an antibiotic called fluoroquinolone.Avelox can be used to treat different types of bacterial infections in the skin, sinuses, or lungs. It is used for treating community-acquired pneumonia. The following are some of the most common problems that plague Chronic bronchitis accompanied by a bacterial infection, as well as bacterial sinusitis.Antibiotics that contain fluoroquinolone may cause severe or permanent side effects.Avelox is only indicated for infections that cannot be treated by a more effective antibiotic.


Avelox may cause serious side effects, such as tendon damage, nerve damage, or serious mood or behavioural changes.If you experience any of the following symptoms, stop using this medication and contact your doctor immediately: headache; irritability; numbness or tingling in your hands or feet; confusion; agitationIf you experience severe pain in the chest, back, or stomach, seek emergency medical attention.Avelox can cause swelling or tears in a tendon. If you experience sudden joint pain, swelling, bruising, or stiffness in any joint, stop taking Avelox immediately and contact your doctor.

Before you take this drug

Avelox should not be used if you have an allergy to moxifloxacin (ciprofloxacin, gemifloxacin, levofloxacin, ofloxacin, or norfloxacin).Moxifloxacin can cause swelling or tears in tendons (the fibres that connect bones to muscles). This is most common in the Achilles tendon in the heel. Avelox can cause this to happen at any time during the treatment or even several months after stopping Avelox. Tendon problems are more common in people over 60 years old, those who take steroids, and those who have undergone a kidney transplant, heart transplant, or lung surgery.

Tell your doctor about any of the following to ensure Avelox will be safe for you:

  • Tendon problems, bone problems, or arthritis
  • Aneurysms, narrowing and hardening of arteries, blood circulation problems;
  • Heart problems high blood pressure
  • A genetic disorder such as ehlers-danlos or marfan syndrome;
  • Diabetes;
  • A muscle or nerve disorder such as myasthenia gravis
  • Liver or kidney disease
  • A seizure, head injury, or brain tumour;
  • Long-qt syndrome
  • Low potassium levels in the blood (hypokalemia)

Avelox is not recommended for anyone under the age of 18.

Inform your doctor if you are pregnant or nursing.

Similar/related drugs

Prednisone, Amoxicillin, Doxycycline, Ciprofloxacin, Cephalexin, Azthromycin, and Metronidazole

How to take  Avelox?

Follow the directions on your prescription label and read all medication guides or instructions sheets. Read all the instructions on the prescription label.Avelox oral can be taken orally.Drink extra water and Avelox along with your medication to help keep your kidneys functioning properly.Avelox can be taken orally with or without food at the same time every day.Avelox is administered as an intravenous infusion. Your healthcare provider may give you your first dose and teach you how to use it properly.Please read and follow all instructions for use that come with your medication. If you don't understand the instructions, reach out for help from either your physician or pharmacist.Only prepare your injection when you're ready to administer it. If the colour of your medicine has changed or if it contains particles, do not use it. For new medication, call your pharmacist.Moxifloxacin should not be injected in the same vein as other medications. Inject slowly and allow at least one hour for the infusion.Even if you feel better quickly, continue to take this medication for the entire prescribed time. You can get an infection resistant to the medication if you skip doses. Avelox does not treat a virus, such as the flu or a cold.Do not share Avelox with anyone.Avelox oral should be stored at room temperature, away from moisture. Do not refrigerate the injection.

What happens if I miss the dose?

If you miss a dose, take it as soon as possible. Skip the missed dose when your next dose is less than eight hours away. Never take two doses in one go.If you missed a dose, call your doctor to get instructions.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

Aviod this

Do not drive or engage in hazardous activities until you have determined how the medicine will affect you. You may be unable to react properly.Antibiotics can cause diarrhoea. This could be an indication of a new illness. Call your doctor if you have bloody or watery diarrhoea before taking anti-diarrhoea medication.Avoid sunbeds and sunlight. Avoid tanning beds or sunlight. When you're outdoors, wear protective clothing and apply sunscreen (SPF 30 or higher). If you experience severe sunburn, rash, or swelling, tell your doctor.

Side effects of Avelox

If you experience any of the following symptoms: hives, difficulty breathing, swelling on your face or in your throat, or severe skin reactions (fever or sore throat with burning eyes, skin pain or blistering, or a red or purple rash),After just one dose, moxifloxacin may cause severe side effects. These include tendon problems, nerve side effects (which could cause permanent nerve damage), mood or behaviour changes that are serious (even after only one dose), and low blood sugar levels (which can lead to a coma).

Do not use this medicine if you are suffering from:

  • Low sugar—headaches, nausea, sweating, and irritability. Dizziness. Nausea. Rapid heart rate.
  • Nerve symptoms in the hands, arms, or legs include numbness and weakness, tingling, or burning pain.
  • Mood or behaviour changes that are serious: nervousness confusion, or agitation; hallucinations; memory problems; or trouble concentrating.
  • Signs of tension rupture: sudden pain, swelling, or bruising; stiffness or tenderness in the joints.

Moxifloxacin can cause damage to the aorta (the main blood vessel of the body) in rare cases. If you experience severe pain in your back, chest, or stomach, seek emergency medical attention.

Stop using Avelox immediately and consult your doctor if:

  • Diarrhoea that is bloody or watery; severe stomach pain
  • Heartbeats that are fast or pounding, chest fluttering, dizziness, or the feeling of passing out;
  • Muscle weakness and breathing problems
  • A seizure (convulsions);
  • Any skin rash;
  • Increased pressure inside the skull; severe headaches or ringing in the ears; vision issues; pain behind your eyelids;
  • Liver disorders: upper stomach discomfort, lack of appetite, dark urine, and clay coloured stools; jaundice; yellowing of the skin or eyelids.

Avelox may cause side effects such as:

  • Nausea, diarrhoea;
  • Dizziness;

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Some medicines may make moxifloxacin less effective if taken together. Take Avelox 4 hours before or 8 hours after taking the other medicine if you are taking any of these medicines:

  • The ulcer medicine sucralfate or antacids containing calcium, magnesium, or aluminium (such as Maalox Milk of Magnesia Mylanta Pepcid Complete Rolaids Tums and others);
  • Didanosine (Videx), powder or chewable tablet;
  • Sevelamer, or lanthanum carbonate.
  • Vitamin or mineral supplements containing aluminium, iron, magnesium, or zinc

Tell your doctor about your other medications, including:

  • Erythromycin;
  • A blood thinner (Warfarin Coumadin Jantoven);
  • A diuretic, or "water pill".
  • Heart rhythm medication
  • Insulin (or oral diabetes medication) (check your blood glucose regularly);
  • Medicine to treat mental illness or depression
  • Steroid medicine (such as prednisone);
  • Nsaids are nonsteroidal anti-inflammatory medications. These include aspirin (Advil), ibuprofen, naproxen, diclofenac (Indomethacin), meloxicam (Aleve), and celecoxib.

This list is incomplete. Moxifloxacin may interact with other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible drug interactions.




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