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Generic names: guaifenesin (pronounced gwye FEN-esin) and pseudoephedrine (pronounced soo-doe EEE-FED-rin).

Brand names: e Ambifed-G, Entex T, Maxifed, Mucinex
Upper respiratory combinations

What is Respaire-30?

This leaflet does not list all the brands or forms of pseudoephedrine and guaifenesin.Guaifenesin acts as an expectorant. Guaifenesin helps to loosen up congestion in the chest and throat, making it easier for you to cough through your mouth.The decongestant pseudoephedrine shrinks the blood vessels within the nasal passages.Dilated blood vessels can cause nasal congestion.Respaire-30 is a combination medication used to treat nasal congestion and sinus congestion and reduce chest congestion due to the common flu or cold.This medication guide does not list all possible uses for Respaire-30.

Side effects of Respaire-30

Seek immediate medical care if you have any of these symptoms: difficulty breathing, swelling in your face, lips, throat, or tongue.Respaire-30 may cause serious side effects. Respaire-30 should be stopped immediately, and you should consult your doctor if:

  • Fast, pounding, or uneven heartbeat;
  • Severe anxiety, or nervousness.

Respaire-30 can cause the following side effects:

  • Dry mouth, nose, or throat
  • Nausea, loss of appetite;
  • Feeling excited or restless, especially in children
  • Sleep problems (insomnia);
  • Headache, dizziness.

There may be other side effects. For medical advice on side effects, call your doctor. To report adverse effects, you can contact the FDA at 1-800-FDA-1088.


This medication should not be given to children younger than four years of age. Ask a doctor first before giving cough and cold medications to children. Children as young as 4 years old can die from the misuse of cough medicines.

Take this medication only if you have been prescribed it.

Respaire-30 should not be used if you have an allergy to it.Respaire-30 should not be used if an MAO inhibitor has been taken in the last 14 days. A dangerous drug interaction may occur. MAO inhibitors are isocarboxazid (linezolid), phenelzine (rasagiline), selegiline (tranylcypromine), and rasagiline.

If you suffer from:

  • High blood pressure Heart Disease Coronary Artery Disease
  • Diabetes;
  • Circulation problems
  • Glaucoma;
  • Overactive thyroid gland;
  • An enlarged prostate, or urination problems.

This medication is not known to be harmful to an unborn child. If you are pregnant, do not use Respaire-30 unless you have been advised by a doctor.Guaifenesin, pseudoephedrine, and other drugs can pass through breast milk to harm nursing babies. Decongestants can also reduce breast milk production. Do not use this medication without consulting a doctor if you are breastfeeding a child.Phenylalanine can be found in artificially sweetened liquid medicines. If you have phenylketonuria, check the label of your medication.

How to take Respaire-30?

Do not exceed the recommended dosage or duration. Use the recommended dose or duration. Do not exceed it. Cold or cough medicine is typically taken for only a few days until symptoms disappear.This medication should not be given to children younger than four years of age. Ask a doctor first before giving cough and cold medicine to children. Children as young as 4 years old can die from the misuse of cough and cold medicines.Use the provided dosing syringe or a dose-measuring cup or spoon to measure liquid medicines. Ask your pharmacist if you don't have a device for measuring doses.You should not open, crush, chew, or break an extended-release capsule or tablet. Swallow the capsule or tablet whole.Chew the chewable tablet before swallowing it.While taking this medication, drink extra fluids in order to loosen congestion and lubricate the throat.If your symptoms don't improve within 7 days or you have a headache, a cough, or a skin rash, call your doctor.Store away from heat and moisture at room temperature.

What happens if I miss the dose?

Respaire-30 can be taken as needed, and there is no set schedule. Take the missed dose immediately if you take the medication regularly. If your next scheduled dosage is approaching, skip the missed dose. You should not take more medicine to compensate for a missed dose.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.

What should be avoided?

This medication can affect your ability to think or react. You should be careful when driving or doing anything else that requires you to remain alert.Respaire-30 and alcohol can have side effects.Before using any other cough, cold, or allergy medicines, consult your doctor or pharmacist. Many combination medicines contain Respaire-30. You can get too much drug when you take certain products in combination.

Interaction with other drug

Before using this medication, ask your doctor or pharmacist if you also use any other medications, such as vitamins and herbal remedies. When used together, some medicines can have unwanted or harmful effects. This medication guide does not list all possible interactions.This medicine can have adverse effects if taken with drugs that cause sleepiness or reduce breathing. Before taking Respaire-30 along with sleeping pills, narcotic pain medicines, muscle relaxers, or medicine for anxiety, depression, or seizures, ask your doctor.