The Web Health



Generic name: primidone [PRIM-i-done]
Name of the brand: Mysoline
Dosage format: oral tablet (250 mg, 50 mg)
The class of drug: barbiturate anticonvulsants

What is Primidone?

Primidone can be described as an anticonvulsant drug that helps to manage seizures.Primidone is also employed for other purposes that are not covered in this guideline.

Side effects of Primidone

See a doctor immediately. If you are experiencing symptoms that are warning signs of reactions to an allergen, such as mouth sores, hives, a skin rash with peeling and blisters, breathing difficulties, or swelling of your lips, face, or tongue,

Inform your doctor about any new or worsening symptoms, such as changes in your mood or behavior, depression, anxiety, or if you are feeling agitated, restless, excessively hyperactive (mentally as well Physically) (physically) about taking your life or hurting your self.

Primidone may cause serious side effects. Contact your doctor immediately in the event of:

  • Strange thoughts or behaviors;
  • Loss of balance or coordination
  • Fever, cold, sore throat;
  • Bleeding or bruising easily.
  • Pale skin, unusual tiredness.

Common adverse effects of primidone could include:

  • Dizziness, drowsiness, or spinning sensation;
  • Problems with balance or muscular movements;
  • Vomiting, vomiting, and loss of appetite.
  • Experiencing fatigue or irritation;
  • Blurred vision
  • The rash
  • Impotence and sexual issues.

This is not a comprehensive list of all the side effects. Other effects may also be present. Talk to your doctor and seek medical advice about the effect. If you have any concerns, report them to the FDA by calling 1-800-FDA-1088.


People are contemplating suicide while they're taking primidone. Be attentive to any changes to your mental state or symptoms. Be sure to report any new or worsening symptoms to your doctor.

Don't stop taking primidone at once, even if you are well. The sudden stop can cause more seizures.

Before you Take this Drug

Primidone should not be used when you have an allergy to either primidone or phenobarbital or are suffering from:

  • Porphyria (a genetic disorder of enzymes that results in symptoms affecting the skin or the nervous system).

Inform your doctor if you have ever suffered from:

  • Depression;
  • A mental disorder
  • Suicidal thoughts or behaviours.

People consider suicide while they take primidone. Your doctor should examine your progress every few appointments. Family members or other carers should be on the lookout for changes in your symptoms or mood.

Do not begin or stop taking seizure medications during pregnancy without consulting your doctor's recommendation. Having a seizure during pregnancy can harm both the baby and the mother. Talk to your doctor when you discover that you are pregnant.

If you're expecting or are expecting, your name might be added to a pregnancy registry in order to track how primidone affects you and the baby. Be sure to inform the doctor who gives birth to your baby of the use of primidone. Both you and the baby could require medications to reduce bleeding during the delivery and right after the birth.

Stop breastfeeding if you notice unusual drowsiness or irritability in the nursing infant. Consult your physician about how to feed your child while taking primidone.

How to Take Primidone?

Follow all the instructions on the label of your prescription and study all medication guides or instruction sheets. The doctor might change your dosage. Follow the medication exactly as prescribed.

If you're switching to primidone from a different seizure medication, then you might have to begin taking primidone only at night. Follow the directions of your doctor.

Don't stop taking primidone abruptly, even if you are well. The abrupt stop can cause more seizures. Follow the instructions of your physician when tapering your dose.

It could take several weeks before you experience the full benefit of using primidone. Your physician will decide the length of time you will be treated with this medication.

If you take this medication over a long period of time, you could require regular medical examinations.

Conserve primidone at room temperature away from light, moisture, and heat.

In the event of an emergency In the event of an emergency, carry or wear medical identification that lets the public know that you take seizure medicine.

What Happens If I Miss a Dose?

Do not take the medicine for as long as you are able, but avoid your missed dose if it's close to the time of the next dose. Don't take two doses at a time.

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Avoid driving or engaging in hazardous activities until you understand how primidone can affect you. Your reaction could be impaired.

Alcohol consumption with this medication may cause more adverse effects.

Interaction with Other Drugs

Utilizing primidone along with other drugs that cause you to become drowsy could cause this to happen more. Consult your physician before taking opioids, a sleeping pill, a muscle relaxer, or medication to treat seizures or anxiety.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories