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Generic Name: Nateglinide (oral) (oral) Na-ta-GLYnde [na-ta-GLUE-nude]
The Brand Name is Starlix.
Dosage Format: (120 mg, 60 mg)Oral tablet
Class of Drug: Meglitinides

What is Nateglinide?

Nateglinide is used along with exercise and a healthy diet to increase blood sugar control in people suffering from type 2 diabetes mellitus. Nateglinide isn't a cure for type 1 diabetes.

Additional diabetes drugs are often prescribed together with nateglinide when required.Nateglinide is also employed for other purposes that are not covered in this guideline.

Side effects of Nateglinide

Contact a medical professional immediately in the event that you exhibit symptoms that indicate an allergy, such as hives, breathing difficulties, or swelling of your lips, face, or tongue.

Nateglinide could cause serious adverse effects. Consult your physician immediately in the event of:

  • Seizure (convulsions);
  • Jaundice (yellowing of the eyes or skin).

Common adverse effects of nateglinide could include:

  • Nasal stuffiness or runny nose, sneezing, itching, or cold or flu symptoms;
  • Diarrhea;
  • Lower back pain;
  • Dizziness;
  • Joint discomfort and stiffness.

This is not a comprehensive list of possible side effects, and other side effects could occur. Consult your physician for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

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It is not recommended to use Nateglinide if you suffer from diabetes ketoacidosis (call your physician for treatment).

Before you take this drug

It is not recommended to use nateglinide if you have an allergy to this substance or suffer from:

  • Diabetes ketoacidosis (call your doctor to seek treatment).

Inform your doctor if you have ever suffered from:

  • Liver disease

Follow your doctor's advice on taking the drug nateglinide if you are pregnant or are planning to get pregnant. Controlling diabetes is essential during pregnancy, and being diagnosed with high blood sugar levels can cause problems for both the mother and the baby.It is not recommended to use this medicine while breastfeeding.

Nateglinide is not a prescription drug for anyone under 18 years of age.

How to Take Nateglinide?

Be sure to follow the instructions on your prescription label as well as read the medication guide as well as the instructions. Follow the medication exactly as prescribed.

Nateglinide is usually taken three times per day, every one to 30 minutes prior to eating. If you do not eat your meal, don't consume your dose of nateglinide. Wait until your next meal.

There is a possibility that you are suffering from lower levels of blood sugar (hypoglycemia) and experiencing extreme hunger and dizziness, as well as being irritable or anxious. It can also make you feel confused, anxious, or shakey. To cure hypoglycemia, take a snack or drink a quick-acting food source that contains sugar (fruit juice crackers, hard candy raisins, or other non-diabetic soda).

The doctor might prescribe the use of a glucose injection kit in the event that you suffer from severe hypoglycemia. It is important that your family or friends are aware of the procedure for giving you this injection in the event of an emergency.Also, look out for symptoms of high blood sugar levels (hyperglycemia), like increased thirst or increased urination.

The levels of blood sugar are affected when there is illness, stress, surgery, alcohol consumption, exercise, or avoiding meals. Talk to your doctor prior to making changes to your medication or dosage schedule.Nateglinide is just one component of a treatment plan that could also include exercise, diet, controlling weight, blood sugar tests, and medical treatment. Follow your doctor's advice carefully.

Keep at room temperature, free of heat and moisture.

Details on dosage

Usual Adult Dose for Diabetes Type 2:

The initial dose is 60–120 mg orally three times a day prior to meals.
Maintenance dosage: 60–120 mg taken orally three times per day, before meals.
For patients who are close to the HbA1c target when treatment begins, the first dosage is recommended to be 60 mg orally three times.
Patients should take this medication for a period of 1 to 30 minutes prior to meals; in the event that a meal is skipped, the dose that is scheduled to be administered with the meal is not recommended to prevent hypoglycemia.
This medication should not be used for patients suffering from type 1 diabetes mellitus or to treat diabetic ketoacidosis.
Use as an addition to exercise and diet to help improve the control of glycemic levels in adults suffering from type 2 diabetes mellitus.

What happens If I miss a dose?

Start taking your dose as fast as you are able, but only when you are making preparations for eating the meal. If you do not eat a meal, skip the missed dose and wait until the next meal. Don't take two doses at a time.

What happens If I overdose?

Get medical attention immediately or contact the Poison Help line at 1-800-222-1222. There are signs of low blood sugar like severe weakening, blurred vision, sweating or difficulty speaking, tremors, stomach pain, confusion, and seizures (convulsions).

What should be avoided?

Do not drink alcohol. It reduces blood sugar levels and can interfere with treatment for diabetes.

Interaction with other drugs

Nateglinide may not perform better when you are taking other medications at the same time. Certain medications can result in fewer symptoms of hypoglycemia. This makes it harder to recognize when your blood sugar levels are low. This applies to prescription and over-the-counter medications, vitamins, and herbal supplements. The interactions between these products are not included in this list. Discuss with your doctor any medication you begin or stop taking.



Prescription only

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