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Generic name: cilostazol [sye-LOE-sta-zol]
Drug classes: miscellaneous cardiovascular agents, platelet aggregation inhibitors

It is believed that the Pletal brand name was removed within the U.S. If the generic versions of this product are approved by the FDA, it is possible that there are similar generic versions available.

What is Pletal?

Pletal can be described as a vasodilator. It helps relax the muscles in your blood vessels. This will aid in dilation (widening). This medicine dilates the arteries, which bring liquid to the legs. This medication helps improve circulation by preventing platelets in the blood from clumping and clotting.

Pletal is used to treat the signs associated with chronic claudication. The condition results in decreased blood flow to the legs, which causes pain when walking. This medication helps you walk longer distances with less discomfort. Pletal can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Pletal

See a doctor immediately. If you are experiencing warning signs of an allergic response, such as hives, difficulty breathing, and swelling of your lips, face, and tongue,

Pletal can trigger severe adverse effects. Contact your doctor immediately. If you suffer from:

  • Chest pain, heartbeats that pound, or a heartbeat that is fluttering;
  • A feeling of lightheadedness, as if you're passing out;
  • Fever, the chills, the sore throat, mouth sores, or
  • Simple bleeding, unusual bruises, and red or purple spots on your skin.

Common negative side effects of Pletal can include:

  • Diarrhea, abnormal bowel movements;
  • Headache or
  • Rapid or heartbeats that pound.

This isn't a complete list of possible side effects, and other effects may also be experienced. Contact your physician to seek medical advice on adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

cilostazol, pentoxifylline, Trental, and Pentoxil


Don't take Pletal in the event of heart insufficiency of any type.

Before you take this drug

It is not recommended to use Pletal in case you suffer from heart failure of any type. This medication can make this problem more severe.

Speak to your doctor if you have ever suffered from:

  • Bleeding issues;
  • Kidney or liver disease;
  • A heart stroke (or stroke; or
  • If you smoke.

It is unclear if Pletal could harm an unborn child. Consult your physician if you are pregnant or planning to be pregnant.Breastfeeding is not advised when using Pletal.

How to take Pletal ?

Follow the directions on the prescription label and review all medication guides and instructions. Make sure you use the medication exactly as prescribed.

Pletal is generally taken twice every day with an empty stomach. It is taken at least 30 minutes prior to or two hours after dinner or breakfast.

Use the medicine at the same time every day.

It could take up to 12 weeks before symptoms begin to improve. Continue to take the medication according to the directions and inform your physician if your symptoms persist after 3 years of therapy.

Keep it at room temperature, far from heat and moisture.

Do I be concerned if I miss a dose?

Do not take the medicine for as long as you can. However, do not take your missed dose if it's nearing the time to take the next dose. Don't take two doses at a time.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Grapefruit can be in contact with the pleural area and can cause undesirable adverse negative effects. Do not use grapefruit-related products.

Interaction with other drugs

It is sometimes not safe to take certain medicines simultaneously. Certain drugs may affect the blood levels of the other drugs you are taking, which could cause more side effects or make the drugs less effective.

Numerous drugs can impact Pletal. This includes prescription as well as over-the-counter drugs, vitamins, and herbal remedies. The interactions between these products are not included in this list. Discuss with your physician your current medications as well as any medication you begin or stop taking.