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[Generic name: Dinutuximab DIN-ue TUX-i-mab]

Class: Miscellaneous antineoplastics

What is Unituxin?

Unituxin is a component of other medications used in the treatment of neuroblastoma (a rare cancer of the nervous system) in children.

Unituxin is typically administered when a child has experienced some improvement after other treatments.Unituxin is also used for reasons not mentioned in this guideline for medication.

Side effects of Unituxin

Take immediate medical attention. If your child shows symptoms warning of reactions to an allergen, like hives, trouble breathing, and swelling of the lips, face, and tongue,There are some side effects that can happen after the injection or for up to 24 hours later. Talk to your child's caretaker when your child is feeling dizzy or lightheaded or has a rash on their skin, an eruption, chest tightness, wheezing, trouble breathing, or a swelling on the face.

The condition is known as a capillary leak, and it's a very rare but serious adverse effect. Contact your physician immediately. If your child is showing symptoms of this condition, For example, a runny nose or stuffy eyes, fatigue or thirst, less urination, difficulty breathing, sudden swelling, or weight gain

Unituxin may harm red blood cells, which can lead to irreparable kidney failure. Contact your doctor immediately when your child experiences unusual bleeding or bruising, pale skin, irritability, confusion or irritability, stomach ache, red or bloody diarrhea, pink or red urine swelling, rapid weight gain, and infrequent or no urine.

Contact your doctor immediately. If the child suffers from:

  • Sudden vision loss or vision changes;
  • Headache, confusion, thought problems, seizures;
  • Severe dizziness, or the feeling of fainting;
  • Vomiting, diarrhea, feeling very ill;
  • Nerve disorders: sharp pain or shooting, numbness or tingling discomfort, cold sensation, weakness, difficulty moving, issues with walking or everyday activities loss of bladder or bowel control
  • Low blood cell counts low blood cell counts: fever chills, tiredness, mouth sores, skin sores, easy bruising, abnormal bleeding, pale skin and feet, and feeling lightheaded or short of breath
  • Indications of an imbalance in electrolytes: more thirst or urination, constipation, muscle pain or weakness, leg cramps, tingling or numbness, feeling anxious, having irregular heartbeats, a fluttering sensation in the chest, or a tight feeling.

Common adverse effects of Unituxin can include:

  • Capillary leak syndrome
  • Reacting to an infusion
  • Feeling lightheaded;
  • Pain;
  • Low blood cell count;
  • An electrolyte imbalance;
  • Vomiting, diarrhea;
  • The rash
  • Atypical liver test results

This isn't an exhaustive list of all the side effects. Other side effects could be present. Consult your physician for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Contact your doctor immediately. If your child experiences acute or escalating discomfort, numbness, or tingling, or has difficulty walking or doing everyday activities,

Certain side effects can be observed during the injections or for up to 24 hours afterward, which include dizziness, chest tightness, wheezing, trouble breathing, or swelling on the face.

Before taking this medication, you must consult your physician.

Your child shouldn't receive treatment with Unituxin if you're allergic to it.

Discuss with your doctor if your child has been through:

  • Any kind of bacterial, fungal, or viral disease;
  • An eye problem or a vision issue;
  • Suppression of bone marrow
  • Low bloo d pressure;
  • An electrolyte imbalance (such as blood levels that are low in sodium, potassium, and calcium);
  • Kidney or liver disease and
  • Urinary problems.

How to take Unituxin?

Unituxin is injectable into veins.The injection of Unituxin occurs slowly for 10 to 20 hours.Unituxin is administered in the form of a 28-day treatment. Your child will be given the injection only on specific days during the treatment.The doctor will determine the number of cycles your child will receive.

Your child could be prescribed other medications to combat certain side effects.The child will be observed for at least four hours to ensure that he or she doesn't have an allergic reaction to the medication.Your child might require regular medical examinations, and treatments may be delayed according to the results.

What happens if I miss the dose?

In a medical setting, your child is less likely to skip a dose.

What happens if I overdose?

In a medical facility, an overdose could be taken care of quickly.

What should be avoided?

Follow the doctor's advice regarding any restrictions on your food, drink, or activities.

Interaction with other drugs

Other medications may interact with Unituxin. Other medications can affect Unituxin, such as prescription and over-the-counter medicines, vitamins, and herbal products. Notify your physician of any additional medications you are taking.