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Generically, promethazine (oral) Promethazine (oral) pro-METH-a-zeen
The brand names are Phenergan, Phenadoz, and Promethegan.
Drug classes: antihistamines, phenothiazine antiemetics

Phenergan can also be found in conjunction with other drugs like phenylephrine (Prometh Hydrochloride), codeine (Prometh VC), or dextromethorphan (Promethazine DM).

What is Phenergan?

Phenergan is part of a class of medications known as phenothiazines. It alters the action of chemical substances within your brain. Promethazine is also an antihistamine. It reduces any effects caused by the chemical histamine that is present in your body. Phenergan is a medication used to treat allergic symptoms like itching, a runny nose, sneezing or watery eyes, hives, and itchy skin rashes.

Phenergan is also a remedy for motion sickness and also treats nausea and vomiting as well as discomfort after surgery. Phenergan is also utilized as a sedative or sleep aid. Phenergan is not a remedy for treating asthma symptoms or pneumonia. It is also not recommended for treating other respiratory tract infections.


Stop taking Phenergan immediately and consult your doctor immediately in case you are experiencing twitching or uncontrollable movements in your lips, eyes, face, tongue, or legs. These could be early warning signs of potentially harmful adverse effects. Phenergan is not administered to children less than two years old. Phenergan can cause serious breathing problems or even death in children who are very young. Be sure to follow the directions of your doctor when you administer this medicine to any child at any stage.

Phenergan may cause adverse effects that can affect your reactions or thinking. Be aware of this if you drive or engage in any activity that requires you to stay alert and awake. Avoid drinking alcohol, as it could increase certain adverse effects of phenergan. There are other medications that may be incompatible with promethazine. Discuss with your doctor any prescription or over-the-counter medicines you take. This includes minerals and vitamins, as well as herbal products and medicines prescribed by other doctors. Don't start an entirely new drug without consulting your physician. Keep a note of the medications you take, and provide the list to your physician or other health professional who will treat you.

Prior to use this drug

Phenergan shouldn't be administered to children who are less than two years old. Phenergan may cause breathing issues or even death in infants and children. Be sure to follow the directions of your doctor when you give the medicine to children, regardless of age.

You shouldn't use Phenergan if you are sensitive to promethazine or similar medicines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, and prochlorperazine. trifluperazine or thioridazine. Do not consume Phenergan if you suffer from asthma or another respiratory tract disease. To be sure Phenergan is not harmful to you, inform your doctor if you are suffering from:

  • Asthma, chronic obstructive lung disease (COPD), sleep apnea, or another breathing disorder;
  • A sulfite allergy;
  • Seizure history
  • An immune system that is weak (bone marrow depression);
  • Glaucoma;
  • Prostate enlargement or issues with urination
  • Stomach ulcer or obstruction
  • High blood pressure or heart diseases
  • Liver disease;
  • Tumors of the adrenal gland (pheochromocytoma);
  • Low levels of calcium present in blood (hypocalcemia)
  • If you've ever experienced any serious adverse side effects when using promethazine or any other phenothiazine,

It is not clear if phenergan could affect a newborn baby. Animal studies haven't shown any negative effects. Consult your physician if you are expecting or planning to have a baby while taking this medication.

It is unclear if promethazine is absorbed into breast milk or if it affects the nursing infant. Inform your doctor if you are breastfeeding prior to taking Phenergan.

What should I do to do it? Phenergan?

Use Phenergan exactly as directed by your physician. Follow the directions on the label of your prescription. Your doctor may change your dosage to ensure you are getting the best outcomes. Don't take this medication in smaller or larger quantities or for longer than the recommended time.

Phenergan is usually taken before bed or before meals. To prevent motion sickness, Phenergan generally begins at least one hour prior to travel. If used to treat surgical procedures, phenergan is usually taken at night prior to the surgery. How often you use Phenergan and the frequency of your dose will be contingent on the disease being treated.

Measure the amount of liquid medicine using the dosing syringe that comes with it, a dosing spoon, or a medicine cup. If you don't own an instrument for measuring doses, request one from your pharmacist. one.

If your child is taking this medicine, inform your physician if your child's weight has changed. weight. Phenergan dosages are based on the weight of children, and any change could alter your child's dosage.

Consult your physician if symptoms do not improve or if symptoms get worse when you use Phenergan. This medication can produce unusual results in certain tests. Be sure to inform any doctor treating your condition that you're using Phenergan. Keep Phenergan in a cool, dry place, away from heat, humidity, and light.

What happens if I miss the dose?

You should take the dose you missed as quickly as you can remember. Do not take any missed doses if you are close to the time of the next dose. Don't take any extra medication to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

The symptoms of an overdose can include hyperactive reflexes and a loss of coordination. Other symptoms include extreme drowsiness or weakness, dilation of the pupils, fainting and shallow or weak breathing, and seizures (convulsions).

What should be avoided?

The medicine could affect your ability to think or react. Be cautious if you drive or engage in activities that require that you be aware. Be careful not to get up too fast from lying or sitting in a position. You could be shaky. Make sure to get up slowly and steadily to avoid falling.

Alcohol consumption can cause an increase in the effects of phenergan in certain ways. Don't drink alcohol when taking this medication.

Avoid exposure to the sun as well as tanning beds. Phenergan may cause sunburn more quickly. Protect yourself with protective clothes and sunscreen (SPF 30 or more) while you're outdoors.

Side effects of Phenergan

Contact a medical professional immediately. If you notice any indications that indicate an allergic reaction, like hives, trouble breathing, or swelling of your lips, face, tongue, throat, or face, Stop using Phenergan immediately and contact your doctor immediately. If you are suffering from:

  • Excessive drowsiness; deep or weak breathing;
  • A feeling of lightheadedness, as if you're passing out;
  • Confusion, agitation, hallucinations, and nightmares;
  • Seizure (convulsions);
  • Heartbeats that are slow or fast
  • Jaundice (yellowing of the eyes or skin);
  • Uncontrolled muscle movements in your facial muscles (chewing lipsmacking, chewing mouth movements, frowning, blinking, or eye movements);
  • Bleeding or bruising (nosebleeds and bleeding gums);
  • Suddenly feeling weak or sick or ill-feeling, including fever, chills and sore throats or mouth sores, swelling or red gums, difficulty swallowing; or
  • Very rigid (rigid) muscles cause excessive anxiety, confusion, and sweating. Rapid or irregular heartbeats, it feels like you may be struck.

Other side effects, such as insomnia and extreme drowsiness, could be more prevalent in older adults.

Common Phenergan side effects can include:

  • Drowsiness, dizziness;
  • Ringing in your ears
  • Double vision;
  • Being anxious;
  • Dry mouth dry mouth
  • Tiredness, sleep issues (insomnia)

This isn't an exhaustive list of possible side effects, and others could happen. Contact your doctor for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Medicines for colds or allergies, medications for pain relief, sedatives, sleeping medication, muscle relaxers, and medicines for depression, seizures, or anxiety could interact with Phenergan, causing medical issues or worsening the risk of adverse effects. Inform your physician if you regularly take any of these medications.

Tell your physician if you are taking any of the following drugs:

  • Lithium (Eskalith, Lithobid);
  • Atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others, as well as atropine (Atreza, Sal-Tropine), belladonna (Don Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), and scopolamine (Transderm-Scop);
  • Blood pressure medication, such as guanadrel (Hylorel), guanethidine (Ismelin), propranolol (Inderal), and other blood pressure medications;
  • A blood thinner, such as warfarin (Coumadin);
  • Bronchodilators like Ipratropium (Atrovent) as well as the tiotropium (Spiriva);
  • Bladder or urinary medication like Oxybutynin (Ditropan, Oxytrol), Solifenacin (Vesicare), and many more
  • A MAO inhibitor, such as isocarboxazid (Marplan) or tranylcypromine (Parnate), phenelzine (Nardil), selegiline (Eldepryl, Emsam), or methylene blue injections;
  • Medications to treat those suffering from Parkinson's illness, restless legs syndrome, pituitary gland tumor (prolactinoma), as well as
  • Medication to treat stomach ulcers or irritable bowel syndrome, like dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and many others), mepenzolate (Cantil), and propantheline (Pro-Banthine).

This list isn't complete, and there are numerous other medications that interfere with Phenergan. Inform your doctor of the prescription and non-prescription supplements, including minerals, vitamins, and herbal products, as well as medications prescribed by your doctor. Don't start any new medication without first talking to your doctor. Keep a note of every medication you use. You can show this list to your physician or other health professional who will treat you.