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Generic Name: Sumatriptan (transdermal) [SOO-ma-TRIP-tan]
Drug Class: Antimigraine agents

There is no evidence that the Zecuity brand name has been removed from the U.S. If the Zecuity brand name is generic and is approved by the FDA, There may be similar products that are available in generic form.

What is Zecuity?

Zecuity is a medication for headaches that reduces blood vessels in the brain. Sumatriptan also decreases the amount of substances within the body that can cause nausea, headaches, sensitization to sound and light, and other migraine-related symptoms.Zecuity skin patches are utilized in treating headaches caused by migraine headaches in adults. Sumatriptan is only used to treat headaches that have already started. It cannot stop headaches or decrease the severity of headaches.

Zecuity is not a suitable treatment for treating a typical tension headache or a headache that causes loss of motion in the opposite part of the body. Make sure to use this medicine only in cases where your problem has been diagnosed by a medical professional for migraine headaches.


You don’t need to use Zecuity if you have any history of heart disease or coronary artery disease, blood circulation problems, Wolff-Parkinson-White syndrome, uncontrolled high blood pressure, severe liver disease, circulation problems affecting your intestines, a history of a stroke, or if your headache seems to be different from your usual migraine headaches.

Do not take Zecuity. If you've taken an MAO inhibitor in the past 14 days. A potentially dangerous interaction with a drug could occur. MAO inhibitors are isocarboxazid, linezolid, methylene blue injection, rasagiline, and phenelzine, as well as tranylcypromine.

Do not take Zecuity in the 24 hour period after you have used another migraine medication.

Before you take this drug

It is not recommended to take Zecuity. If you have an allergy to sumatriptan or you are:

  • Angina (chest pain) or blood circulation issues in the heart and the inability to supply blood towards the heart
  • A heart disorder called Wolff-Parkinson-White syndrome;
  • An antecedent family history of heart disease, heart attack, or stroke, which includes "mini-stroke";
  • Untreated or uncontrolled high blood pressure that is not treated or controlled
  • Serious liver diseases;
  • Circulation problems affecting your intestines;
  • A headache that is like a migraine but is not your typical headache.

Don't use Zecuity. If you've been taking an MAO inhibitor in the past 14 days. A potentially dangerous interaction with a drug could occur. MAO inhibitors are isocarboxazid, linezolid, Methylene Blue injection, rasagiline, and phenelzine, as well as tranylcypromine and others.

To ensure Zecuity patches are suitable for you, inform your doctor that you have:

  • Kidney or liver disease;
  • Epilepsy, or any other seizures;
  • Hypertension, a heart rhythm disorder,
  • Risk factors for coronary artery diseases (such as being menopausal, having diabetes, smoking, obesity, having high cholesterol levels, having an ancestral medical history with coronary artery diseases, being over 40, being a male, or being a female who underwent surgery to remove her uterus).

It's possible that the Zecuity transdermal patch can burn the skin if you wear it while undergoing an MRI (magnetic imaging). It is best to remove the patch prior to the test.

It isn't known if Zecuity could harm an unborn baby. Consult your physician if you are expecting or planning to become pregnant.It isn't known if transdermal sumatriptan enters the breast milk of a nursing baby or whether it can harm nursing babies. It is not recommended to breastfeed when taking this medication.

Zecuity is not a product that has been approved to be used by anyone younger than 18 years old.

Similar or related drugs

Ubrelvy, Botox, Diclofenac, Celecoxib, Sumatriptan, Metoclopramide, and Reglan

How to take Zecuity?

Your physician may decide to provide the first dosage of Zecuity in an environment such as a clinic or hospital to address any severe side effects that can happen.

Follow the instructions on the prescription label. Avoid using Zecuity in greater or lesser quantities or for a longer time than suggested. Too much migraine medication can make headaches more severe.Utilize Zecuity whenever you begin to notice symptoms of a headache or when an attack has already begun.Do not consume by mouth. Zecuity transdermal should be used solely on the skin.

Apply the patch to clean, dry, and hairless skin on your thighs or the outside of your upper arm. Avoid skin that is covered with tattoos, scars, an eruption, or another skin condition. Review all information about your patient, including medication guides and instruction sheets given to you. Consult your physician or pharmacist for any additional concerns.Wear only one Zecuity Skin patch at a time. Using extra skin patches won't make the medication more efficient. Don't cut your skin patch.Apply the patch to your skin for four hours or until the dosing light of the LED goes out.

After applying the Zecuity patches to the skin, in the event that your headache isn't gone completely, consult your physician prior to applying another patch. Pick a different spot on your body for your second patch. If the headache disappears and then comes back, you could apply an additional patch if it's been at least two hours since the last patch. Do not apply at least two (2) patches within the space of 24 hours. If your symptoms aren't improving, consult your doctor prior to applying any additional patches.

It is not recommended to apply more than four Zecuity patches to your skin in a month. Your blood pressure could require a check while you use this product.After removing the Zecuity skin patch, fold it in half, put the sticky side inside, and then throw the patch out in a safe place so that pets and children are not able to access it.Keep the patches at room temperature and free of heat and moisture. Avoid storing Zecuity's skin patch in the fridge or freezer.

Make sure to keep Zecuity inside its original packaging and carton until you are prepared to utilize it.

What happens if I miss the dose?

Because Zecuity is only used when it is required, it doesn't follow a routine for daily doses. Consult your doctor immediately if your symptoms do not improve following treatment with Zecuity.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Do not shower, bathe, or bathe while wearing a patch that contains sumatriptan.

Do not take Zecuity for more than 24 hours prior to or after taking another medication to treat migraine headaches, such as:

  • sumatriptan tablets, injection, or nasal spray; almotriptan (Axert); eletriptan (Relpax); frovatriptan (Frova); naratriptan (Amerge); rizatriptan (Maxalt); or zolmitriptan (Zomig);
  • Ergot medicine: dihydroergotamine, ergotamine, ergonovine, and methylergonovine

Sumatriptan can affect your reactions or thinking. Be aware when you drive or perform any activity that requires you to be vigilant.

Side effects of Zecuity

Seek medical attention immediately. If you are experiencing symptoms of an allergic reaction, Zecuity suggests: hives, excessive itching, swelling, feeling lightheaded with pounding heartbeats, difficulty breathing, swelling of your lips, face, and throat.

Take off your Zecuity skin patch and call your doctor immediately. If you are suffering from:

  • Extremely severe skin conditions (redness, pain, discoloration, itching or peeling skin, blistering, cracks, warmth, as well as open wounds) when a patch was applied;
  • Acute stomach pain, bloody diarrhea, and a sudden onset;
  • Extreme chest pain, breathlessness, and irregular heartbeats.
  • Seizure (convulsions);
  • Blood circulation issues: cramps in your hips and legs; tight or heavy sensations in your legs; numbness or tingling sensations within your legs. Muscle weakness, burning foot pain, and a blue or pale-coloured appearance of your toes
  • Blood pressure is dangerously high with severe headaches, unfocused vision, constant pounding in your ears or neck, nosebleeds, as well as anxiety and confusion.
  • Symptoms of a heart attack: the chest hurts or feels pressure; a throbbing pain that spreads into your shoulder or jaw; nausea, sweating, and vomiting
  • Indications of a stroke: the sudden feeling of weakness or numbness (especially in one part of your body) an abrupt, intense headache, slow or distorted speech, difficulties with balance or vision, and
  • Serotonin levels that are elevated within the body cause hallucinations, agitation, and a rapid heart rate. Hyperactive reflexes, nausea, diarrhea, vomiting, loss of coordination, and fainting.

Common zecuity adverse effects could include:

  • Discomfort, numbness or tingling sensations, itching, or minor irritations where a patch was placed;
  • Skin discoloration when the patch was worn or
  • Small skin redness up to 24 hours after the removal of a patch of skin.

This isn't a complete list of all the side effects. Others could happen. Consult your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Utilising Zecuity when you're taking other medicines could cause excessive levels of serotonin to increase within your body, which is known as "serotonin syndrome," which can lead to death. Inform your doctor that you also take:

  • Medication to treat depression;
  • Medication to treat a psychiatric disorder
  • A drug called a narcotic (opioid) medication
  • Medication to stop vomiting and nausea.

This list is not comprehensive. Other medications can interact with sumatriptan. This includes prescription and over-the-counter medicines such as vitamins and herbal products. The interactions of all potential types aren't included in this guideline for medication.