The Web Health



Brand names include Esgic Fioricet Zebutal
Drug class: analgesic combinations

What is the Esgic language?

Acetaminophen can reduce fever, and it relieves pain.Butalbital belongs to a class of medications called barbiturates. It is used to relax the muscles involved in tension headaches.Caffeine stimulates the central nervous system. Caffeine relaxes the muscle contractions of blood vessels, improving blood flow.Esgic, a combination of medicines, is used to treat headaches caused by tension.Esgic can also be used in other ways not mentioned in the medication guide.

Side effects of Esgic

If you experience any of the following symptoms of an allergy: difficulty breathing, hives, swelling in your lips, face, throat, or tongueAcetaminophen can cause severe reactions in some cases. This may happen even if the person has taken it before without any reaction. Call your doctor immediately if the skin is red or you develop a rash. If it spreads, blistering occurs, and you peel.

The side effects of this medicine can be serious. If you experience:

  • Confusion, a seizure;
  • Shortness of breath
  • A feeling of lightheadedness, as if you could pass out.
  • Upper stomach pain; itching; dark urine; and clay-colored stools. Jaundice.

Esgic can cause the following side effects:

  • Drowsiness, dizziness;
  • Feeling lightheaded
  • Nausea, vomiting, and stomach pain;
  • Drunk feeling;
  • Shortness of breath

There may be other side effects. For medical advice on side effects, call your doctor. Report adverse reactions by calling the FDA at 1-800-FDA-1088.


You should not take this medication if you've taken an MAO inhibitor in the last 14 days. In some cases, a dangerous drug-drug interaction can occur. The MAO inhibitors are isocarboxazid (linezolid), methylene blue injection, phenelzine, and tranylcypromine.Don't take this medicine in excess. Overdosing on acetaminophen may cause liver damage or death.Acetaminophen can cause severe reactions in rare instances. If you notice skin redness, a rash, or blistering that causes peeling and blistering, stop taking the medicine immediately and contact your doctor.

Before you take this drug

Esgic should not be used if MAO inhibitors have been taken in the last 14 days. It is possible that a dangerous drug interaction will occur. The MAO inhibitors are isocarboxazid (linezolid), phenelzine (phenelzine), rasagiline, selegiline, and tranylcypromine.Esgic should not be used if the user is allergic, has porphyria, or has recently taken alcohol, sedatives, tranquilizers, or other opioids.

If you've ever:

  • Liver diseases, such as cirrhosis. A history of alcoholism and drug addiction
  • Kidney disease
  • Stomach bleeding
  • A history of a skin or rash due to any medications;
  • A history of mental illness or thoughts of suicide.

Unknown is whether or not this medication will harm an unborn child. Your baby may become addicted to butalbital if you take it while pregnant. Withdrawal symptoms can be life-threatening for the newborn. A baby's addiction to habit-forming drugs may require medical care for up to several weeks. Inform your doctor that you plan to get pregnant or are currently pregnant.The medicine may pass through breast milk, causing harm to a baby who is nursing. You should tell your doctor that you are nursing a child.No one under the age of 12 is allowed to use this product.

How to take Esgic?

Do not exceed the dosage recommended on your prescription. Take only the recommended dose. An overdose can damage your liver or cause death. If the medication seems to be less effective in relieving pain, tell your doctor.Butalbital can be addictive. Do not share the medicine, particularly with someone who has a drug addiction or abuse history. Store it in an area where other people cannot access it. It is illegal to sell or give away the medicine.Keep away from heat and moisture. Store at room temperature.Track the quantity of medication used in each bottle. You should know that butalbital can be abused, and you need to keep track of who is taking your medication without a prescription or improperly.

What happens if I miss the dose?

Esgic can be used as needed, and you do not need to follow a schedule. Use the missed dose as quickly as possible if you have a regular schedule. If your next dose is approaching, skip the missed dose. You should not take extra medication to compensate for a missed dose.

What happens if I overdose?

Call Poison Help at 1-800-222-1222 or seek emergency medical care. An overdose can lead to death.Loss of appetite, nausea, and vomiting are the first symptoms of an overdose. Other signs include confusion, weakness, or sweating. Other symptoms include dark urine and yellowing skin or whites of the eyes.Other symptoms of overdose include insomnia or restlessness. Other symptoms are diarrhea and increased shallow breathing.

Avoid this

The medication may cause adverse effects, which can impair your ability to think or react. You should be careful when driving or doing anything else that requires alertness.Alcohol is harmful to your liver. Acetaminophen can increase the risk of liver injury.Before using other cold or allergy medications, sleep medications, or pain medications, consult your doctor. Many combination medications contain acetaminophen, also known as APAP. Taking some products with each other can result in an overdose of acetaminophen, which is fatal.Avoid taking caffeine, diet pills, or stimulants, such as ADHD medication, without consulting your doctor.

Interaction with other drug

Esgic can have dangerous side effects if taken with drugs like sleeping pills, opioid pain medicines, muscle relaxers, and medications for depression or epilepsy.Esgic may be affected by other drugs, such as prescription or over-the-counter medications, vitamins, and herbal products. Inform your doctor of all the other medications you take.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories