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Hadlima Prefilled Syringe

Generic name: adalimumab [AY-da-LIM-ue-mab]
Brand Names: Abrilada Amjevita Cyltezo Hadlima Prefilled Syringe Hulio
Drug classes: antirheumatics, TNF-alpha inhibitors

What is a Hadlima Prefilled Syringe?

Hadlima Syringe Prefilled is used in conjunction with methotrexate for the treatment of rheumatoid arthritis and juvenile idiopathic arthritis.Had Lima prefilled syringes can be used to treat inflammatory conditions in both adults and children, including Crohn's, juvenile idiopathic ulcerative colitis, rheumatoid arthritis, psoriatic arthritis, ankylosing sclerosis, plaque, and hidradenitis. Adalimumab is used in adults only for some brand forms.The Hadlima prefilled syringe can be used in other ways not mentioned in the medication guide.

Side Effects of Hadlima Prefilled Syringe

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: difficulty breathing, swelling in your face, lips, or throat, or hives.

If you experience any of the symptoms of lymphoma, call your doctor immediately.

  • Fever, swollen glands, body aches and sweats, feeling unwell,
  • Pale skin, rash, or easy bleeding or bruising;
  • Feeling light-headed or cold feet and hands;
  • Pain in the upper abdomen that can spread to your shoulder
  • Feeling full after only eating a small portion, weight reduction

Call your doctor immediately if you:

  • Skin changes, such as pus-filled bumps or red, scaly spots;
  • New or worsening heart conditions: swelling, rapid weight increase, feeling of shortness of breath
  • Liver problems: loss of appetite, pain in the upper right corner of the stomach, fatigue, itchiness, dark urine, clay-colored stools, jaundice
  • Joint pain or similar symptoms such as muscle or lupus, flu, or a rash that gets worse in the sun;
  • Nervous system problems: numbness, tingling, or tingling in the hands or feet; dizziness or vision problems;
  • Signs of tuberculosis include fever, cough, and night sweats.

If you experience certain side effects, your treatment may be suspended or discontinued permanently.

Side effects of the Hadlima prefilled syringe include:

  • Headache, skin rash;
  • Sore or stuffy throat, or cold symptoms such as stuffy nose, sinus pain, and sneezing.
  • Pain, redness, or rash where the injection was administered.

There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA in regards to potential side effects is easy: dial 1-800-FDA-1088!


You could get serious or even fatal infections. Contact your doctor immediately if you experience flu-like symptoms, such as night sweats, confusion, or vision problems. Your doctor will test you for infections or tuberculosis before you use the Hadlima prefilled syringe.You may experience hepatitis B after stopping the use of the Hadlima prefilled synthetic syringe. You may require liver function tests every few months.

Before you take this drug

Tell your doctor before you use the Hadlima prefilled syringe if you experience any symptoms of infection. These include fever, chills and coughs, body aches or sores, fatigue, and open wounds. Other symptoms may include diarrhea or stomach pain.Tell your doctor about any recent travel or exposure to fungal infections. You may get exposed to certain infections when you travel.

Inform your physician of any of the following issues:

  • Tuberculosis, or if someone in your family has it,
  • An active or chronic infection
  • Cancer;
  • Hepatitis B
  • Congestive heart failure;
  • Any numbness, tingling, or muscle disorder, such as multiple sclerosis or Guillain-Barre syndrome
  • An allergic reaction to rubber or latex;
  • Scheduled to undergo major surgery
  • You have recently received or will be receiving any vaccine.

Before you use the Hadlima prefilled syringe, make sure that you have all your vaccines up to date.The use of a Hadlima prefilled syringe can increase your risk of developing other types of cancer. Discuss this matter with your physician.The harm caused to an unborn child by the Hadlima prefilled syringe is unknown. Inform your doctor if you are pregnant or planning to become pregnant.Inform your doctor about the use of the Hadlima prefilled syringe while pregnant. This could impact your baby's vaccine schedule.A doctor can tell you if you are safe to breastfeed when using the Hadlima prefilled syringe.

How to take Hadlima Prefilled Syringe?

Take care to read all instructions or guides included with your medication, and follow them precisely. Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed.The Hadlima-prefilled syringe will be injected into the skin. You will be taught how to use this medication by a healthcare provider. Do not repeat the injection in the same area.Only prepare an injection when you're ready to give it. If the medicine is cloudy, has changed color, or has particles in it, call your pharmacist. If you're not sure how to inject a medicine, ask your pharmacist or doctor.Weight is used to determine the dose for children and adolescents. If your child loses or gains weight, the dose may change.You could get infected more easily. This includes serious infections that can be fatal. You'll need to undergo frequent medical tests.Your doctor will perform a test to determine if you have tuberculosis or any other infection. You will have your blood tested both before and after treatment with this medication.Hadlima Prefilled Syringe may make your hepatitis B worse or come back during treatment. You may require liver function tests during treatment and for a few months after stopping the medication.

Do not freeze. Store the medicine in its original packaging in the refrigerator. Keep away from the light. Follow all instructions carefully for how to store your medication during travel. Avoid extremes of heat or cold.Do not heat the medicine with hot water, sunlight, or a microwave. Never warm up the medicine in hot water, the sun, or the microwave.After one use, throw away the prefilled syringes or auto-injectors, even if they still contain medicine.Never reuse a syringe or needle. Put them in a "sharps container" that is puncture-proof, and dispose of the sharps according to local or state laws. Keep away from children and pets.

What happens if I miss the dose?

Do not take two doses at once. Never take two doses of the same medication at once.

What happens if I overdose?

Reach out for poison assistance immediately or seek medical care as soon as possible by dialing 1-800-222-1222.

What should be avoided?

Avoid injecting into hard, red, or bruised skin that has a swollen, tender surface, scars, stretch marks, etc.Avoid being around people who are sick.If you suspect an infection, notify your physician immediately.You could get a serious infection if you receive a "live vaccine". Live vaccines are measles (MMR), rubella, rotavirus (typhoid), yellow fever, varicella, chickenpox, and zoster.

Interaction with other drug

It is sometimes not safe to take certain medications at the same time. Some drugs may affect the blood levels of drugs that you are taking, causing side effects or making them less effective.

Tell your doctor if you are taking any other medications, including:

  • Abatacept, etanercept;
  • Anakinra;
  • Azathioprine, 6-mercaptopurine,
  • Certolizumab, golimumab, infliximab, and rituximab.

This list is incomplete. Hadlima Prefilled Syringe may be affected by other drugs, such as prescription and over-the-counter medicines and vitamin and herb products. This list does not include all possible interactions with other drugs.