The Web Health


Pentam 300

Generic Name: Pentamidine [pen-TAM-e-deen]
Brand Names: Nebupent, Pentam 300
Classification of Drugs: Inhaled anti-infectives, miscellaneous antibiotics

What is Pentam 300?

Pentam 300 is an antifungal drug that fights infections caused by fungus.Pentam 300 is used to stop and treat pneumonia caused through Pneumocystis Jiroveci (Carinii).Pentam 300 may also be used for reasons not mentioned in this guideline.

Side effects of Pentam 300

See a doctor immediately. If you notice any of the following symptoms that indicate reactions to an allergen: hives; trouble breathing; or swelling of your lips, face, and tongue.

Pentam 300 may cause serious adverse reactions. Consult your doctor immediately if you experience:

  • Wheezing, choking, or other breathing problems following the use of this medication using a nebulizer
  • A feeling of lightheadedness, as if you're passing out;
  • Rapid or irregular heart rate;
  • Urination that is painful or difficult
  • Confusion, hallucinations;
  • Discomfort, burning, or skin changes after the injection was administered;
  • Worsening symptoms or signs of the onset of new symptoms or signs of new symptoms (fever, cough, night sweats, trouble breathing);
  • A blood cell disorder characterized by pale skin, feeling lightheaded or shaky, bleeding that is not normal, and easy bruising in red or purple spots on your skin
  • Pancreatitis—severe discomfort in your stomach that spreads into the back of your body, vomiting along with nausea;
  • Low blood sugar: headache and hunger, sweating, dizziness, confusion, irritability, jittery feeling,
  • Severe skin reaction: fever, sore throat, swelling of your tongue or face, burning eyes, pain in your skin, and an irritated or purple rash that spreads (especially on the face or upper body) and can cause blisters and peeling.

Common negative side effects associated with pentam 300 may include:

  • Lack of appetite
  • A strange or unpleasant taste is present inside the mouth.

It's not a comprehensive listing of all possible adverse consequences, but other consequences could also occur. Consult your doctor for guidance about medical-related adverse reactions. If you experience any side negative effects to the FDA by calling 1-800-FDA-1088.

Similar/related drugs

Clindamycin, Bactrim, sulfamethoxazole, trimethoprim, Bactrim DS, Cleocin, dapsone, and leucovorin


Follow the directions on your prescription label and the package. Be sure to inform your health care providers about your medical ailments, allergies, and any medications you take.

Before you take this drug

It is not recommended to use Pentam 300 if you are allergic to it.

To be sure Pentam 300 is safe for you, consult your physician if you suffer from:

  • Blood pressure (or lower blood pressure;
  • A heart rhythm disorder
  • Diabetes, also known as low blood sugar (hypoglycemia),
  • A pancreas disorder;
  • A severe skin rash called stevens-johnson syndrome;
  • Anemia (low red blood cells);
  • Low white blood cell count or lower platelet levels in the blood.
  • Low levels of calcium or the high level of potassium present in your blood.
  • Kidney disease, liver failure,
  • A past history of tobacco use or the presence of asthma.

FDA classification for pregnancy C It isn't known what the risk is that Pentam 300 will harm an unborn baby. Consult your physician if you are expecting or plan to become pregnant while taking this medication.

It isn't known if pentamidine gets into breast milk or if it is harmful to nursing babies. It is not recommended to breastfeed when taking Pentam 300.Inhaled Pentam 300 shouldn't be administered to children without the guidance of an experienced physician.

How to take the Pentam 300?

Pentam 300 can be taken by injection or as an inhaled drug by using the nebulizer. Follow the directions on the prescription label. Don't use this medication in smaller or larger amounts or for a longer time than the recommended time.

Pentam 300 is a powder medicine that has to be mixed with liquid (diluent) prior to use for injection or in a nebulizer. If you're using the medicine at home, make sure you know how to blend and keep the medication. Only use the diluent supplied in your prescription.

To make use of Pentam 300 as an injection:

  • Pentam 300 is injected into muscles or into the vein via an IV. You can be instructed on how to administer an IV at home. Don't inject yourself with this medication when you don't know how to administer the injection, and safely dispose of any needles that are no longer needed, such as IV tubing, IV needles, and other tools that are used to inject the medication.
  • Don't use Pentam 300 if it has changed color or has particles. Contact your pharmacist to inquire about a new medication.
  • Inform your doctor if you experience any pain, burning, or swelling in the area of your needle during the time Pentam 300 is injected.
  • Use a disposable needle only once and then dispose of it in a container that is puncture-proof (ask your pharmacist where to get one and the best way to get rid of it). Keep the container away from animals and children.

To utilize Pentam 300 with a nebulizer:

  • After mixing the medicine with the diluent, you can pour the entire mixture into the nebulizer's chamber. Attach the mask or mouthpiece, and then connect the chamber for the drug with the compressor.
  • Do not mix other medications with the nebulizer Pentam 300.
  • Relax and sit upright in a comfortable place. The mouthpiece should be placed in your mouth, or you should put on a mask that covers your mouth and nose. Switch on the compressor.
  • Breathe slowly and gradually until no more mist has formed from the nebulizer and the chamber for the drug is empty.
  • Clean the nebulizer after every use. Follow the cleaning instructions included with your nebulizer.

If you're diabetic, make sure you take note of your blood sugar when you take Pentam 300. Pentam 300 can increase or decrease your blood sugar levels.

When taking Pentam 300, you may require regular blood tests. The function of your heart may have to be assessed by using an electrocardiograph (sometimes also referred to as an EKG).Place unmixed medications in a cool, dry place at room temperature, away from heat, moisture, and light.

Mixed medicine should be used within a set number of hours, based on the diluting agent. Be sure to follow the instructions for mixing and storage that are included in your medicine. Talk to your pharmacist if you have any questions.Pentam 300 contains no preservatives. Get rid of any medicine that has been used up.

What happens If I miss a dose?

Consult your physician for directions in case you missed a dose of Pentam 300.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or activities.

Interaction with other drugs

Other medications can interact with pentamidine. This includes prescription and non-prescription medicines, vitamins, and herbal products. Be sure to inform your health professionals about any medications you take currently and any medications that you decide to stop or change your use of.